STRINGSTRING
EPHA2 EPHA2 LTF LTF NR1H4 NR1H4 OAS3 OAS3 OAS2 OAS2 PLA2G2A PLA2G2A DEFB135 DEFB135 LACRT LACRT DCD DCD ZNFX1 ZNFX1 CFP CFP SFTPD SFTPD RBCK1 RBCK1 NLRP10 NLRP10 LGALS4 LGALS4 IL17A IL17A AQP1 AQP1 CXCL6 CXCL6 RNF213 RNF213 G3R3U7_GORGO G3R3U7_GORGO G3RI71_GORGO G3RI71_GORGO IFNE IFNE IL18 IL18 DEFB129 DEFB129 RNF31 RNF31 WFDC13 WFDC13 DEFA5 DEFA5 SLPI SLPI G3RJR8_GORGO G3RJR8_GORGO G3RJS0_GORGO G3RJS0_GORGO DHX15 DHX15 S100A14 S100A14 PLA2G6 PLA2G6 PYCARD PYCARD BPIFA2 BPIFA2 STAB1 STAB1 RNASE3 RNASE3 PPP1R11 PPP1R11 FCER1G FCER1G DEFB136 DEFB136 G3RQR5_GORGO G3RQR5_GORGO WFDC11 WFDC11 NOS2 NOS2 IL6 IL6 JCHAIN JCHAIN IRGM IRGM G3RSR8_GORGO G3RSR8_GORGO G3RSU6_GORGO G3RSU6_GORGO TIRAP TIRAP LYG1 LYG1 PRB4 PRB4 LEAP2 LEAP2 G3RVT8_GORGO G3RVT8_GORGO S100A8 S100A8 G3RWV9_GORGO G3RWV9_GORGO SHARPIN SHARPIN G3RXV4_GORGO G3RXV4_GORGO TLR4 TLR4 ENSGGOP00000021036 ENSGGOP00000021036 PPBP PPBP PI3 PI3 PRH1 PRH1 LYPD8 LYPD8 RAB14 RAB14 NOD1 NOD1 CCL20 CCL20 CRP CRP G3S3W8_GORGO G3S3W8_GORGO IRF8 IRF8 G3S7D0_GORGO G3S7D0_GORGO TBK1 TBK1 FGA FGA DEFB113 DEFB113 G3SAQ4_GORGO G3SAQ4_GORGO G3SBB4_GORGO G3SBB4_GORGO LALBA LALBA G3SBD9_GORGO G3SBD9_GORGO DEFB112 DEFB112 DEFB125 DEFB125 G3SDI2_GORGO G3SDI2_GORGO G3SDT0_GORGO G3SDT0_GORGO LCN2 LCN2 OAS1 OAS1 TNFRSF1A TNFRSF1A STATH STATH WFDC12 WFDC12 BPIFA1 BPIFA1 TLR3 TLR3 UMOD UMOD ENSGGOP00000027573 ENSGGOP00000027573 HAVCR2 HAVCR2 RNASE6 RNASE6 G3SHX6_GORGO G3SHX6_GORGO LYG2 LYG2 G3SIL0_GORGO G3SIL0_GORGO RAG2 RAG2 G3SIQ4_GORGO G3SIQ4_GORGO MARCHF2 MARCHF2 G3SJS6_GORGO G3SJS6_GORGO VGF VGF ENSGGOP00000037298 ENSGGOP00000037298 GSE1 GSE1 TSLP TSLP ENSGGOP00000037086 ENSGGOP00000037086 DEFB103A DEFB103A ENSGGOP00000036847 ENSGGOP00000036847 ENSGGOP00000036130 ENSGGOP00000036130 ANG ANG OPTN OPTN SLAMF8 SLAMF8 FCGR1A FCGR1A GSDMB GSDMB ENSGGOP00000033674 ENSGGOP00000033674 ENSGGOP00000032812 ENSGGOP00000032812 CHGA CHGA DEFB115 DEFB115 G3SK86_GORGO G3SK86_GORGO ANXA3 ANXA3 SYK SYK ENSGGOP00000032772 ENSGGOP00000032772 HTN3 HTN3 ENSGGOP00000032091 ENSGGOP00000032091 LYST LYST ENSGGOP00000031506 ENSGGOP00000031506 RNASE4 RNASE4 IL7R IL7R ZG16 ZG16 H2BC12 H2BC12 S100A9 S100A9 PGLYRP4 PGLYRP4 PGLYRP3 PGLYRP3 IL6R IL6R G3QER9_GORGO G3QER9_GORGO FGR FGR HAMP HAMP G3QEF1_GORGO G3QEF1_GORGO PGLYRP2 PGLYRP2 LYZL6 LYZL6 TF TF GBP6 GBP6 NOD2 NOD2 RIPK2 RIPK2 DEFA4 DEFA4 DEFA6 DEFA6 LYZ LYZ PGLYRP1 PGLYRP1 SEH1L SEH1L ADM ADM NLRP1 NLRP1 IL27RA IL27RA DEFB1 DEFB1 PRKD1 PRKD1 MPEG1 MPEG1 CLEC4E CLEC4E G3R9F3_GORGO G3R9F3_GORGO ACP5 ACP5 CAMP CAMP WFDC10A WFDC10A C10orf99 C10orf99 G3RAL4_GORGO G3RAL4_GORGO DEFB128 DEFB128 ADAM17 ADAM17 PRH2 PRH2 SLC11A1 SLC11A1 SHC1 SHC1 GBP4 GBP4 G3RD46_GORGO G3RD46_GORGO G3RD86_GORGO G3RD86_GORGO FGB FGB GALP GALP CXCL13 CXCL13 CALCA CALCA IL10 IL10 G3RES3_GORGO G3RES3_GORGO G3RG63_GORGO G3RG63_GORGO G3SK93_GORGO G3SK93_GORGO TREM2 TREM2 RPS19 RPS19 HTN1 HTN1 GSDMA GSDMA IL17F IL17F NLRP3 NLRP3 SPN SPN WFDC3 WFDC3 DEFA1B DEFA1B IL22RA1 IL22RA1 IL12B IL12B GSDMC GSDMC NOTCH2 NOTCH2 MYD88 MYD88 G3QM93_GORGO G3QM93_GORGO DEFB106A DEFB106A DEFB118 DEFB118 AICDA AICDA ENSGGOP00000051553 ENSGGOP00000051553 ENSGGOP00000050852 ENSGGOP00000050852 TMF1 TMF1 ENSGGOP00000050208 ENSGGOP00000050208 ENSGGOP00000050054 ENSGGOP00000050054 RNASE11 RNASE11 ENSGGOP00000049719 ENSGGOP00000049719 ENSGGOP00000048920 ENSGGOP00000048920 ENSGGOP00000048843 ENSGGOP00000048843 RARRES2 RARRES2 MPO MPO ENSGGOP00000048129 ENSGGOP00000048129 TREM1 TREM1 REG3G REG3G ENSGGOP00000047482 ENSGGOP00000047482 TAC1 TAC1 ROMO1 ROMO1 ENSGGOP00000046335 ENSGGOP00000046335 ENSGGOP00000046102 ENSGGOP00000046102 ENSGGOP00000046073 ENSGGOP00000046073 ENSGGOP00000045870 ENSGGOP00000045870 NLRP6 NLRP6 ENSGGOP00000045214 ENSGGOP00000045214 CEBPB CEBPB ANKRD17 ANKRD17 ENSGGOP00000043190 ENSGGOP00000043190 G3QRK3_GORGO G3QRK3_GORGO TNFRSF14 TNFRSF14 RBPJ RBPJ NAIP NAIP ENSGGOP00000041630 ENSGGOP00000041630 ENSGGOP00000041400 ENSGGOP00000041400 ENSGGOP00000041365 ENSGGOP00000041365 DEFB104A DEFB104A DEFB134 DEFB134 G3QRP1_GORGO G3QRP1_GORGO G3QRR1_GORGO G3QRR1_GORGO G3QRT3_GORGO G3QRT3_GORGO G3QS82_GORGO G3QS82_GORGO FPR2 FPR2 G3QT71_GORGO G3QT71_GORGO G3QT76_GORGO G3QT76_GORGO CD36 CD36 DEFB116 DEFB116 IL1B IL1B DEFB107A DEFB107A SSC5D SSC5D ENSGGOP00000040622 ENSGGOP00000040622 ENSGGOP00000040509 ENSGGOP00000040509 RPL30 RPL30 COCH COCH MBL2 MBL2 DEFB126 DEFB126 RNASE7 RNASE7 G3RXM3_GORGO G3RXM3_GORGO ENSGGOP00000038658 ENSGGOP00000038658 C5AR1 C5AR1 RAB1A RAB1A CD4 CD4 PRKCD PRKCD RNASE9 RNASE9 EPX EPX TLR2 TLR2 WFDC5 WFDC5 DEFB121 DEFB121 RNASE1 RNASE1 NLRC4 NLRC4 FAU FAU SPON2 SPON2 AKIRIN2 AKIRIN2 G3QIQ2_GORGO G3QIQ2_GORGO LCE3B LCE3B COLEC12 COLEC12 GBP2 GBP2 IL23A IL23A SCNN1B SCNN1B DEFB110 DEFB110 SELP SELP G3QF49_GORGO G3QF49_GORGO DEFB123 DEFB123 IL23R IL23R DEFB132 DEFB132 G3QUU9_GORGO G3QUU9_GORGO PLA2G1B PLA2G1B G3QV30_GORGO G3QV30_GORGO S100A12 S100A12 IL12A IL12A F2 F2 ADAMTS5 ADAMTS5 DEFB105A DEFB105A WFDC9 WFDC9 TUSC2 TUSC2 SERPINE1 SERPINE1 PLAC8 PLAC8 G3QX42_GORGO G3QX42_GORGO G3QX51_GORGO G3QX51_GORGO GBP7 GBP7 RPL39 RPL39 CLEC4D CLEC4D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EPHA2EPH receptor A2. (876 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1087 aa)
OAS22'-5'-oligoadenylate synthetase 2. (687 aa)
PLA2G2APhospholipase A(2). (144 aa)
DEFB135Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (77 aa)
LACRTLacritin. (137 aa)
DCDDermcidin. (120 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
CFPComplement factor properdin. (469 aa)
SFTPDSurfactant protein D. (375 aa)
RBCK1Uncharacterized protein. (204 aa)
NLRP10NLR family pyrin domain containing 10. (661 aa)
LGALS4Galectin. (323 aa)
IL17AInterleukin 17A. (155 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
CXCL6C-X-C motif chemokine. (114 aa)
RNF213Ring finger protein 213. (5254 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
G3RI71_GORGONACHT domain-containing protein. (1127 aa)
IFNEInterferon epsilon. (208 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
DEFB129Beta-defensin 129; Has antibacterial activity; Belongs to the beta-defensin family. (183 aa)
RNF31Uncharacterized protein. (1072 aa)
WFDC13WAP four-disulfide core domain 13. (93 aa)
DEFA5Defensin alpha 5. (94 aa)
SLPISecretory leukocyte peptidase inhibitor. (132 aa)
G3RJR8_GORGOUncharacterized protein. (113 aa)
G3RJS0_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (81 aa)
DHX15DEAH-box helicase 15. (795 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PYCARDPYD and CARD domain containing. (195 aa)
BPIFA2BPI fold containing family A member 2. (249 aa)
STAB1Stabilin 1. (2570 aa)
RNASE3Eosinophil cationic protein; Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity (By similarity). (160 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
FCER1GUncharacterized protein. (112 aa)
DEFB136Defensin beta 136. (78 aa)
G3RQR5_GORGOIg-like domain-containing protein. (117 aa)
WFDC11WAP four-disulfide core domain 11. (87 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
IL6Interleukin 6. (234 aa)
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)
IRGMImmunity related GTPase M. (181 aa)
G3RSR8_GORGOHaptoglobin; Belongs to the peptidase S1 family. (371 aa)
G3RSU6_GORGOUncharacterized protein. (499 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
LYG1Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family. (194 aa)
PRB4Uncharacterized protein. (156 aa)
LEAP2Liver enriched antimicrobial peptide 2. (77 aa)
G3RVT8_GORGOIg-like domain-containing protein. (215 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
G3RWV9_GORGOUncharacterized protein. (178 aa)
SHARPINSHANK associated RH domain interactor. (387 aa)
G3RXV4_GORGOUncharacterized protein. (345 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa)
ENSGGOP00000021036annotation not available (839 aa)
PPBPC-X-C motif chemokine. (128 aa)
PI3Peptidase inhibitor 3. (117 aa)
PRH1Proline rich protein HaeIII subfamily 1. (189 aa)
LYPD8LY6/PLAUR domain containing 8. (237 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
CCL20C-C motif chemokine. (96 aa)
CRPPentaxin. (224 aa)
G3S3W8_GORGOIg-like domain-containing protein. (175 aa)
IRF8Interferon regulatory factor 8. (426 aa)
G3S7D0_GORGOIg-like domain-containing protein. (200 aa)
TBK1TANK binding kinase 1. (729 aa)
FGAFibrinogen alpha chain. (866 aa)
DEFB113Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (107 aa)
G3SAQ4_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (66 aa)
G3SBB4_GORGORibosomal_L7Ae domain-containing protein. (133 aa)
LALBALactalbumin alpha; Belongs to the glycosyl hydrolase 22 family. (142 aa)
G3SBD9_GORGODEFSN domain-containing protein. (55 aa)
DEFB112Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (112 aa)
DEFB125Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. (157 aa)
G3SDI2_GORGOMajor histocompatibility complex, class I-related; Belongs to the MHC class I family. (341 aa)
G3SDT0_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (213 aa)
OAS12'-5'-oligoadenylate synthetase 1. (414 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
STATHStatherin. (62 aa)
WFDC12WAP four-disulfide core domain protein 12; Antibacterial protein. Putative acid-stable proteinase inhibitor (By similarity). (110 aa)
BPIFA1BPI fold containing family A member 1. (256 aa)
TLR3Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa)
UMODUromodulin. (690 aa)
ENSGGOP00000027573annotation not available (93 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (301 aa)
RNASE6Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. (150 aa)
G3SHX6_GORGOIGv domain-containing protein. (91 aa)
LYG2Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family. (212 aa)
G3SIL0_GORGOAdhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1570 aa)
RAG2Recombination activating 2. (527 aa)
G3SIQ4_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (61 aa)
MARCHF2Membrane associated ring-CH-type finger 2. (246 aa)
G3SJS6_GORGOBPI fold containing family C. (466 aa)
VGFUncharacterized protein. (336 aa)
ENSGGOP00000037298Uncharacterized protein. (51 aa)
GSE1Gse1 coiled-coil protein. (1213 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
ENSGGOP00000037086Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (72 aa)
DEFB103ABeta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. (67 aa)
ENSGGOP00000036847Uncharacterized protein. (51 aa)
ENSGGOP00000036130Uncharacterized protein. (51 aa)
ANGAngiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). (147 aa)
OPTNOptineurin. (577 aa)
SLAMF8SLAM family member 8. (285 aa)
FCGR1AUncharacterized protein. (374 aa)
GSDMBGasdermin B. (416 aa)
ENSGGOP00000033674Ig-like domain-containing protein. (119 aa)
ENSGGOP00000032812Uncharacterized protein. (173 aa)
CHGAChromogranin A. (458 aa)
DEFB115Defensin beta 115. (88 aa)
G3SK86_GORGOS100 calcium binding protein A7 like 2. (106 aa)
ANXA3Annexin. (325 aa)
SYKTyrosine-protein kinase. (635 aa)
ENSGGOP00000032772Uncharacterized protein. (104 aa)
HTN3Histatin 3. (51 aa)
ENSGGOP00000032091Caspase 4; Belongs to the peptidase C14A family. (377 aa)
LYSTLysosomal trafficking regulator. (3790 aa)
ENSGGOP00000031506DEFENSIN domain-containing protein. (93 aa)
RNASE4Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (147 aa)
IL7RInterleukin 7 receptor. (458 aa)
ZG16Zymogen granule protein 16. (167 aa)
H2BC12Histone H2B; Belongs to the histone H2B family. (126 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
PGLYRP4Peptidoglycan recognition protein 4. (373 aa)
PGLYRP3Peptidoglycan recognition protein 3. (341 aa)
IL6RInterleukin 6 receptor. (468 aa)
G3QER9_GORGOElastase, neutrophil expressed; Belongs to the peptidase S1 family. (246 aa)
FGRTyrosine-protein kinase. (529 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
G3QEF1_GORGOUncharacterized protein. (282 aa)
PGLYRP2Peptidoglycan recognition protein 2. (634 aa)
LYZL6Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family. (148 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
GBP6Guanylate binding protein family member 6. (633 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
DEFA4Defensin alpha 4. (97 aa)
DEFA6Defensin alpha 6. (100 aa)
LYZLysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents; Belongs to the glycosyl hydrolase 22 family. (148 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
ADMAdrenomedullin. (185 aa)
NLRP1NLR family pyrin domain containing 1. (1471 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
DEFB1Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (68 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
MPEG1Macrophage expressed 1. (716 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
G3R9F3_GORGOUncharacterized protein. (4211 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
CAMPCathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family. (173 aa)
WFDC10AWAP four-disulfide core domain 10A. (79 aa)
C10orf99Chromosome 10 open reading frame 99. (81 aa)
G3RAL4_GORGOMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (354 aa)
DEFB128Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (92 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
PRH2Proline rich protein HaeIII subfamily 2. (149 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
SHC1SHC adaptor protein 1. (584 aa)
GBP4Guanylate binding protein 4. (640 aa)
G3RD46_GORGOCathepsin G; Belongs to the peptidase S1 family. (255 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
FGBFibrinogen beta chain. (491 aa)
GALPGalanin like peptide. (116 aa)
CXCL13C-X-C motif chemokine. (109 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
IL10Interleukin 10. (178 aa)
G3RES3_GORGOUncharacterized protein. (133 aa)
G3RG63_GORGOISG15 ubiquitin like modifier. (165 aa)
G3SK93_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
RPS19Ribosomal protein S19. (145 aa)
HTN1Histatin 1. (57 aa)
GSDMAGasdermin A. (445 aa)
IL17FInterleukin 17F. (163 aa)
NLRP3NLR family pyrin domain containing 3. (1028 aa)
SPNSialophorin. (399 aa)
WFDC3WAP four-disulfide core domain 3. (234 aa)
DEFA1BDEFENSIN domain-containing protein. (94 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (574 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
GSDMCGasdermin C. (507 aa)
NOTCH2Notch receptor 2. (2373 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa)
G3QM93_GORGOUncharacterized protein. (79 aa)
DEFB106ABeta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. (65 aa)
DEFB118Beta-defensin 118; Has antibacterial activity; Belongs to the beta-defensin family. (123 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
ENSGGOP00000051553annotation not available (126 aa)
ENSGGOP00000050852annotation not available (362 aa)
TMF1TATA element modulatory factor 1. (1092 aa)
ENSGGOP00000050208annotation not available (126 aa)
ENSGGOP00000050054MORN repeat containing 5. (175 aa)
RNASE11RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (170 aa)
ENSGGOP00000049719Uncharacterized protein. (51 aa)
ENSGGOP00000048920Ribosomal_L7Ae domain-containing protein. (93 aa)
ENSGGOP00000048843Sushi domain-containing protein. (109 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
MPOMyeloperoxidase. (747 aa)
ENSGGOP00000048129Caspase recruitment domain family member 9. (536 aa)
TREM1IG domain-containing protein. (249 aa)
REG3GRegenerating family member 3 gamma. (175 aa)
ENSGGOP00000047482Ig-like domain-containing protein. (155 aa)
TAC1Tachykinin precursor 1. (129 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
ENSGGOP00000046335Uncharacterized protein. (118 aa)
ENSGGOP00000046102Small proline rich protein 2A. (72 aa)
ENSGGOP00000046073Protein S100; Belongs to the S-100 family. (101 aa)
ENSGGOP00000045870Uncharacterized protein. (108 aa)
NLRP6Uncharacterized protein. (912 aa)
ENSGGOP00000045214Fib_alpha domain-containing protein. (288 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
ANKRD17Ankyrin repeat domain 17. (2496 aa)
ENSGGOP00000043190Uncharacterized protein. (234 aa)
G3QRK3_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (88 aa)
TNFRSF14Uncharacterized protein. (193 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
NAIPUncharacterized protein. (198 aa)
ENSGGOP00000041630Uncharacterized protein. (75 aa)
ENSGGOP00000041400MACPF domain-containing protein. (686 aa)
ENSGGOP00000041365Drosha ribonuclease III. (1380 aa)
DEFB104ABeta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family. (72 aa)
DEFB134Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (66 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
G3QRR1_GORGOUncharacterized protein. (124 aa)
G3QRT3_GORGOGranulysin. (173 aa)
G3QS82_GORGOBeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (73 aa)
FPR2N-formyl peptide receptor 2; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (By similarity). Binding of FMLP to the receptor causes activation of neutrophils (By similarity). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5- stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity). (350 aa)
G3QT71_GORGOLymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
DEFB116Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (107 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
DEFB107ABeta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
SSC5DUncharacterized protein. (941 aa)
ENSGGOP00000040622Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (159 aa)
ENSGGOP00000040509Beta-defensin 103A. (67 aa)
RPL30Ribosomal_L7Ae domain-containing protein. (115 aa)
COCHCochlin. (550 aa)
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (248 aa)
DEFB126Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] (111 aa)
RNASE7Ribonuclease A family member 7; Belongs to the pancreatic ribonuclease family. (156 aa)
G3RXM3_GORGOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSGGOP00000038658ANK_REP_REGION domain-containing protein. (398 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
RAB1ARAB1A, member RAS oncogene family. (205 aa)
CD4CD4 molecule. (458 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
RNASE9Inactive ribonuclease-like protein 9; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family. (210 aa)
EPXEosinophil peroxidase. (715 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
WFDC5WAP four-disulfide core domain protein 5; Putative acid-stable proteinase inhibitor. (224 aa)
DEFB121Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (76 aa)
RNASE1Ribonuclease pancreatic; Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double- stranded RNA (By similarity). (156 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
FAU40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (136 aa)
SPON2Spondin 2. (331 aa)
AKIRIN2Akirin 2. (203 aa)
G3QIQ2_GORGOStabilin 2. (2459 aa)
LCE3BLate cornified envelope 3B. (95 aa)
COLEC12Collectin subfamily member 12. (742 aa)
GBP2Guanylate binding protein 2. (591 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (685 aa)
DEFB110Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)
SELPSelectin P. (830 aa)
G3QF49_GORGOAzurocidin 1. (251 aa)
DEFB123Beta-defensin 123; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)
IL23RInterleukin 23 receptor. (629 aa)
DEFB132Beta-defensin 132; Has antibacterial activity; Belongs to the beta-defensin family. (94 aa)
G3QUU9_GORGOProtein S100; Belongs to the S-100 family. (101 aa)
PLA2G1BPhospholipase A(2). (148 aa)
G3QV30_GORGOGasdermin D. (532 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
DEFB105ABeta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family. (78 aa)
WFDC9WAP four-disulfide core domain 9. (89 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
PLAC8Placenta associated 8. (115 aa)
G3QX42_GORGOBactericidal permeability increasing protein. (487 aa)
G3QX51_GORGOLipopolysaccharide binding protein. (481 aa)
GBP7Guanylate binding protein 7. (638 aa)
RPL39Uncharacterized protein. (51 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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