STRINGSTRING
ERBB4 ERBB4 CDC42 CDC42 TEK TEK PTK2B PTK2B PDGFB PDGFB KIT KIT LYN LYN PRKD1 PRKD1 NOD2 NOD2 EPHA8 EPHA8 FLT1 FLT1 PDGFRB PDGFRB PIK3R4 PIK3R4 CCL19 CCL19 AGAP2 AGAP2 VAV2 VAV2 CCR7 CCR7 CD19 CD19 SRC SRC TNFAIP8L3 TNFAIP8L3 PTK2 PTK2 IRS1 IRS1 ENSGGOP00000041668 ENSGGOP00000041668 CCL21 CCL21 TGFB1 TGFB1 FLT3 FLT3 FGR FGR ATG14 ATG14 VAV3 VAV3 AMBRA1 AMBRA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
CDC42Cell division cycle 42. (191 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
LYNTyrosine-protein kinase. (512 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
EPHA8EPH receptor A8. (1005 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
CCL19C-C motif chemokine. (98 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1080 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
CD19CD19 molecule. (556 aa)
SRCTyrosine-protein kinase. (542 aa)
TNFAIP8L3TNF alpha induced protein 8 like 3. (292 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
ENSGGOP00000041668Fibroblast growth factor receptor. (808 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
FGRTyrosine-protein kinase. (529 aa)
ATG14Autophagy related 14. (492 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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