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| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1689 aa) |
| | ENSGGOP00000035220 | Thioredoxin domain-containing protein. (136 aa) |
| | ENSGGOP00000035282 | Bromo domain-containing protein. (601 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (477 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (848 aa) |
| | ENSGGOP00000036570 | PRELI/MSF1 domain-containing protein. (196 aa) |
| | ENSGGOP00000037735 | Uncharacterized protein. (471 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | ENSGGOP00000040205 | Galectin. (355 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | TMEM131L | Transmembrane 131 like. (1569 aa) |
| | ENSGGOP00000041365 | Drosha ribonuclease III. (1380 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (686 aa) |
| | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) |
| | ENSGGOP00000050525 | PRELI/MSF1 domain-containing protein. (213 aa) |
| | ENSGGOP00000051678 | Butyrophilin subfamily 2 member A2. (523 aa) |
| | ENSGGOP00000045588 | Uncharacterized protein. (654 aa) |
| | ENSGGOP00000051974 | HMG box domain-containing protein. (359 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | IL27 | Interleukin 27. (244 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (768 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | ENSGGOP00000024523 | annotation not available (408 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (114 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (387 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) |
| | MDK | Midkine. (143 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa) |
| | PRDX2 | Peroxiredoxin 2. (198 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (718 aa) |
| | G3RXR2_GORGO | HMG box domain-containing protein. (369 aa) |
| | MALT1 | MALT1 paracaspase. (824 aa) |
| | CD80 | CD80 molecule. (287 aa) |
| | G3RVS4_GORGO | Signal transducer and activator of transcription. (787 aa) |
| | G3RV54_GORGO | Protein tyrosine phosphatase receptor type C. (1306 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (215 aa) |
| | G3RT38_GORGO | ADAM metallopeptidase domain 8. (824 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) |
| | G3RRC5_GORGO | Uncharacterized protein. (491 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | VNN3 | CN hydrolase domain-containing protein. (501 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa) |
| | G3RMA5_GORGO | Tyrosine-protein phosphatase non-receptor type. (415 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1054 aa) |
| | G3RK43_GORGO | Actin like 6B; Belongs to the actin family. (358 aa) |
| | PBRM1 | Polybromo 1. (1665 aa) |
| | G3RIU1_GORGO | Interleukin 36 beta. (164 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | G3RHG3_GORGO | Phosphoinositide-3-kinase regulatory subunit 6. (746 aa) |
| | G3RH36_GORGO | Interferon lambda 1. (200 aa) |
| | NFKBID | ANK_REP_REGION domain-containing protein. (465 aa) |
| | PHF10 | PHD finger protein 10. (469 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | G3RGJ9_GORGO | Kinase; Belongs to the inositol phosphokinase (IPK) family. (757 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (211 aa) |
| | G3RFF0_GORGO | Fibronectin type-III domain-containing protein. (369 aa) |
| | SHB | SH2 domain containing adaptor protein B. (411 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa) |
| | IRF1 | Interferon regulatory factor. (325 aa) |
| | ARID2 | AT-rich interaction domain 2. (1834 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) |
| | NKAP | NFKB activating protein. (416 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | RHOA | Uncharacterized protein. (179 aa) |
| | SOX13 | SRY-box transcription factor 13. (622 aa) |
| | SOX4 | Transcription factor SOX. (444 aa) |
| | LILRB4 | Ig-like domain-containing protein. (342 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (526 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | PRELID1 | PRELI domain containing 1. (219 aa) |
| | G3R7T7_GORGO | AT-rich interaction domain 1B. (2015 aa) |
| | G3R7S6_GORGO | CD74 molecule. (296 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | FANCA | FA complementation group A. (1454 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | G3R560_GORGO | Lymphoid enhancer binding factor 1. (399 aa) |
| | G3R516_GORGO | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | SMAD7 | MH2 domain-containing protein. (211 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | IL4I1 | Amine oxidase. (589 aa) |
| | G3R317_GORGO | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | FOXN1 | Forkhead box N1. (648 aa) |
| | GLI2 | GLI family zinc finger 2. (1537 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (291 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1127 aa) |
| | CLPTM1 | CLPTM1 regulator of GABA type A receptor forward trafficking. (655 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte associated protein 4. (223 aa) |
| | G3QXK1_GORGO | Zinc finger protein 683. (524 aa) |
| | CAMK4 | Calcium/calmodulin dependent protein kinase IV. (419 aa) |
| | FOXJ1 | Forkhead box J1. (421 aa) |
| | AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1213 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | G3QUJ1_GORGO | C-type lectin domain-containing protein. (237 aa) |
| | CD83 | CD83 molecule. (205 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | TNFSF18 | TNF superfamily member 18. (199 aa) |
| | G3QSI4_GORGO | Ring finger and CCCH-type domains 1. (1093 aa) |
| | G3QSH5_GORGO | Tyrosine-protein kinase. (1124 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | CD2 | CD2 molecule. (351 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1073 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1028 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | CD27 | CD27 molecule. (260 aa) |
| | G3QPJ0_GORGO | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | G3QP21_GORGO | Vanin 1. (513 aa) |
| | SLC46A2 | Solute carrier family 46 member 2. (475 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (575 aa) |
| | LAG3 | Lymphocyte activating 3. (525 aa) |
| | RARA | Uncharacterized protein. (624 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (662 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | HLX | H2.0 like homeobox. (495 aa) |
| | EGR3 | Early growth response 3. (349 aa) |
| | TESPA1 | Thymocyte expressed, positive selection associated 1. (521 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | PRDM1 | PR/SET domain 1. (825 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | DUSP10 | Dual specificity phosphatase 10. (399 aa) |
| | G3QGN8_GORGO | Tyrosine-protein kinase. (599 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (470 aa) |
| | G3QF38_GORGO | Forkhead box P3. (441 aa) |
| | G3QDY6_GORGO | Interleukin 7. (179 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | CD46 | CD46 molecule. (399 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (887 aa) |
| | LOXL3 | Lysyl oxidase like 3. (753 aa) |
| | IRF4 | Interferon regulatory factor 4. (451 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | ENSGGOP00000048162 | HMG box domain-containing protein. (352 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa) |
| | FGL2 | Fibrinogen like 2. (439 aa) |
| | CBFB | Core-binding factor subunit beta. (182 aa) |
| | IHH | HH_signal domain-containing protein. (113 aa) |
| | ENSGGOP00000049238 | Uncharacterized protein. (383 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1108 aa) |
| | BRD7 | Bromodomain containing 7. (652 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1023 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | G3SKL0_GORGO | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (377 aa) |
| | IL7R | Interleukin 7 receptor. (458 aa) |
| | ADA | Adenosine deaminase. (412 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1510 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (167 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | TCF7 | HMG box domain-containing protein. (300 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ENSGGOP00000034312 | FA complementation group D2. (1390 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2258 aa) |
