Your Input: | |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | G3QU00_GORGO | Uncharacterized protein. (567 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | VEGFC | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (230 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (556 aa) |
| | ENSGGOP00000048540 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | JCAD | Junctional cadherin 5 associated. (1359 aa) |
| | ENSGGOP00000047246 | annotation not available (97 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (281 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | ENSGGOP00000043657 | Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa) |
| | DDAH1 | Uncharacterized protein. (185 aa) |
| | ENSGGOP00000042710 | Integrin beta. (813 aa) |
| | ENSGGOP00000042193 | Pyruvate kinase; Belongs to the pyruvate kinase family. (310 aa) |
| | RRAS | RAS related. (218 aa) |
| | ENSGGOP00000040217 | Uncharacterized protein. (371 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) |
| | F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | PDCL3 | Phosducin like 3. (239 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa) |
| | APELA | Apelin receptor early endogenous ligand. (54 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (733 aa) |
| | MTDH | Metadherin. (612 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (600 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa) |
| | ENSGGOP00000031606 | Stromal interaction molecule 1. (791 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | G3SK08_GORGO | Uncharacterized protein. (877 aa) |
| | KLF4 | Kruppel like factor 4. (479 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | G3SIC3_GORGO | Uncharacterized protein. (337 aa) |
| | CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | TLR3 | Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa) |
| | G3SCD5_GORGO | Vasohibin 2. (355 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | TJP1 | Uncharacterized protein. (336 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) |
| | C3 | Complement C3. (1663 aa) |
| | PDPK1 | Protein kinase domain-containing protein. (347 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1016 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (347 aa) |
| | CD34 | CD34 molecule. (385 aa) |
| | CD40 | CD40 molecule. (277 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1824 aa) |
| | TBXA2R | Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | G3S6C5_GORGO | CTCK domain-containing protein. (143 aa) |
| | G3S4A9_GORGO | Jumonji domain containing 8. (334 aa) |
| | MDK | Midkine. (143 aa) |
| | ITGAX | Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa) |
| | SPHK1 | Sphingosine kinase 1. (472 aa) |
| | S100A1 | Protein S100; Belongs to the S-100 family. (147 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | NINJ1 | Ninjurin 1. (152 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | HPSE | Heparanase. (543 aa) |
| | G3RQ61_GORGO | Integrin beta; Belongs to the integrin beta chain family. (694 aa) |
| | RTN4 | Reticulon. (1192 aa) |
| | G3RS38_GORGO | Phosducin domain-containing protein. (234 aa) |
| | G3RT40_GORGO | Pyruvate kinase; Belongs to the pyruvate kinase family. (469 aa) |
| | HSPB6 | Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (160 aa) |
| | G3RVQ9_GORGO | Uncharacterized protein. (480 aa) |
| | WARS2 | Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa) |
| | ECM1 | Uncharacterized protein. (540 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | G3RXW1_GORGO | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa) |
| | BTG1 | Uncharacterized protein. (165 aa) |
| | GATA6 | GATA binding protein 6. (596 aa) |
| | RLN2 | Relaxin 2. (185 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | EPHA1 | EPH receptor A1. (976 aa) |
| | EMILIN2 | Elastin microfibril interfacer 2. (1031 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa) |
| | ADAM12 | ADAM metallopeptidase domain 12. (909 aa) |
| | ENG | Endoglin. (654 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | G3QGV2_GORGO | Zinc finger protein 304. (706 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | C5 | Complement C5. (1646 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | CHRNA7 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (358 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | CYSLTR1 | Cysteinyl leukotriene receptor 1. (337 aa) |
| | RAMP2 | Receptor activity modifying protein 2. (175 aa) |
| | G3QVZ5_GORGO | Hyaluronidase. (435 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (837 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | G3QXY3_GORGO | Cytochrome b-245 beta chain. (570 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | ERAP1 | Aminopeptidase. (948 aa) |
| | CELA1 | Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (258 aa) |
| | ISL1 | ISL LIM homeobox 1. (351 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (382 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (591 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (422 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1190 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | SIRT1 | Sirtuin 1. (751 aa) |
| | ANXA3 | Annexin. (325 aa) |
| | AGGF1 | Uncharacterized protein. (715 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | G3R5D7_GORGO | Uncharacterized protein. (366 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (868 aa) |
| | SEMA5A | Semaphorin 5A. (1041 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) |
| | VEGFB | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (168 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | G3R9L0_GORGO | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | G3RA25_GORGO | Sp1 transcription factor. (786 aa) |
| | G3RAC9_GORGO | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (457 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | TNN | Tenascin N. (1299 aa) |
| | IL10 | Interleukin 10. (178 aa) |
| | ANGPTL4 | Angiopoietin like 4. (406 aa) |
| | G3RF44_GORGO | Forkhead box C2. (442 aa) |
| | PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (221 aa) |
| | C3AR1 | Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (482 aa) |
| | CMA1 | Chymase 1; Belongs to the peptidase S1 family. (252 aa) |
| | G3RHG3_GORGO | Phosphoinositide-3-kinase regulatory subunit 6. (746 aa) |
| | SLC39A12 | Solute carrier family 39 member 12. (691 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | GRN | Granulin precursor. (593 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (406 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | NOS3 | Nitric oxide synthase 3. (997 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | ANGPTL3 | Angiopoietin like 3. (460 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1196 aa) |
| | CCL24 | SCY domain-containing protein. (64 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
