(12 nodes) Negative regulation of cell size network (Gorilla gorilla)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSGGOP00000043833	FERM domain-containing protein. (517 aa)
	AKT1S1	AKT1 substrate 1. (276 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	RDX	Radixin. (604 aa)
	DEPTOR	DEP domain containing MTOR interacting protein. (409 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
	UCN	Urocortin. (124 aa)
	RHOA	Uncharacterized protein. (179 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	G3RNB7_GORGO	Uncharacterized protein. (661 aa)
	ENSGGOP00000051899	FERM domain-containing protein. (488 aa)
	TSC1	TSC complex subunit 1. (1164 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1S1	DEPTOR	ENSGGOP00000023242	ENSGGOP00000004308	AKT1 substrate 1.	DEP domain containing MTOR interacting protein.	0.986
AKT1S1	MTOR	ENSGGOP00000023242	ENSGGOP00000010372	AKT1 substrate 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.999
AKT1S1	PTEN	ENSGGOP00000023242	ENSGGOP00000000877	AKT1 substrate 1.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.450
AKT1S1	TSC1	ENSGGOP00000023242	ENSGGOP00000028241	AKT1 substrate 1.	TSC complex subunit 1.	0.459
DEPTOR	AKT1S1	ENSGGOP00000004308	ENSGGOP00000023242	DEP domain containing MTOR interacting protein.	AKT1 substrate 1.	0.986
DEPTOR	MTOR	ENSGGOP00000004308	ENSGGOP00000010372	DEP domain containing MTOR interacting protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.999
DEPTOR	TSC1	ENSGGOP00000004308	ENSGGOP00000028241	DEP domain containing MTOR interacting protein.	TSC complex subunit 1.	0.450
ENSGGOP00000043833	RHOA	ENSGGOP00000043833	ENSGGOP00000012527	FERM domain-containing protein.	Uncharacterized protein.	0.508
ENSGGOP00000051899	RHOA	ENSGGOP00000051899	ENSGGOP00000012527	FERM domain-containing protein.	Uncharacterized protein.	0.508
G3RNB7_GORGO	MTOR	ENSGGOP00000017283	ENSGGOP00000010372	Uncharacterized protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.658
G3RNB7_GORGO	RHOA	ENSGGOP00000017283	ENSGGOP00000012527	Uncharacterized protein.	Uncharacterized protein.	0.413
G3RNB7_GORGO	TSC1	ENSGGOP00000017283	ENSGGOP00000028241	Uncharacterized protein.	TSC complex subunit 1.	0.517
MTOR	AKT1S1	ENSGGOP00000010372	ENSGGOP00000023242	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	AKT1 substrate 1.	0.999
MTOR	DEPTOR	ENSGGOP00000010372	ENSGGOP00000004308	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	DEP domain containing MTOR interacting protein.	0.999
MTOR	G3RNB7_GORGO	ENSGGOP00000010372	ENSGGOP00000017283	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.658
MTOR	PTEN	ENSGGOP00000010372	ENSGGOP00000000877	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.719
MTOR	RHOA	ENSGGOP00000010372	ENSGGOP00000012527	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.948
MTOR	TSC1	ENSGGOP00000010372	ENSGGOP00000028241	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	TSC complex subunit 1.	0.930
PTEN	AKT1S1	ENSGGOP00000000877	ENSGGOP00000023242	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	AKT1 substrate 1.	0.450
PTEN	MTOR	ENSGGOP00000000877	ENSGGOP00000010372	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.719