STRINGSTRING
G3QN04_GORGO G3QN04_GORGO MOXD1 MOXD1 CITED1 CITED1 DDC DDC ENSGGOP00000029826 ENSGGOP00000029826 SNCA SNCA PAH PAH TRPC1 TRPC1 HDC HDC SLC6A3 SLC6A3 G3RXC1_GORGO G3RXC1_GORGO TPH1 TPH1 G3RJI7_GORGO G3RJI7_GORGO TYRP1 TYRP1 DBH DBH SLC24A5 SLC24A5 PMEL PMEL DAO DAO TPH2 TPH2 NR4A2 NR4A2 G3R664_GORGO G3R664_GORGO CTNS CTNS TYR TYR DDTL DDTL KL KL GATA3 GATA3 HAND2 HAND2 OCA2 OCA2 SLC45A2 SLC45A2 G3QPK5_GORGO G3QPK5_GORGO GPR37 GPR37 MFSD12 MFSD12 PNMT PNMT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QN04_GORGOTyrosine hydroxylase. (528 aa)
MOXD1Monooxygenase DBH like 1. (613 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
DDCDopa decarboxylase. (489 aa)
ENSGGOP00000029826Uncharacterized protein. (123 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
PAHPhenylalanine hydroxylase. (452 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
HDCHistidine decarboxylase. (662 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
G3RXC1_GORGOPKD domain-containing protein. (598 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
G3RJI7_GORGODopachrome tautomerase. (552 aa)
TYRP1Tyrosinase related protein 1. (537 aa)
DBHDopamine beta-hydroxylase. (617 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
PMELPKD domain-containing protein. (582 aa)
DAOD-amino acid oxidase. (347 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
G3R664_GORGOUncharacterized protein. (226 aa)
CTNSCystinosin, lysosomal cystine transporter. (400 aa)
TYRTyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. (471 aa)
DDTLUncharacterized protein. (164 aa)
KLUncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (739 aa)
GATA3GATA binding protein 3. (444 aa)
HAND2Heart and neural crest derivatives expressed 2. (198 aa)
OCA2OCA2 melanosomal transmembrane protein. (837 aa)
SLC45A2Solute carrier family 45 member 2. (530 aa)
G3QPK5_GORGOTransforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GPR37G protein-coupled receptor 37. (613 aa)
MFSD12Major facilitator superfamily domain containing 12. (481 aa)
PNMTPhenylethanolamine N-methyltransferase. (282 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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