STRINGSTRING
ENSGGOP00000032627 ENSGGOP00000032627 FKBP8 FKBP8 DLL4 DLL4 ISL2 ISL2 G3S9R1_GORGO G3S9R1_GORGO FEZF2 FEZF2 ENSGGOP00000024523 ENSGGOP00000024523 ZNF521 ZNF521 MYT1L MYT1L G3RTH8_GORGO G3RTH8_GORGO BCL11B BCL11B TBR1 TBR1 G3RPS4_GORGO G3RPS4_GORGO SOX9 SOX9 GBX1 GBX1 PROX1 PROX1 BMP4 BMP4 DBX1 DBX1 LHX3 LHX3 SHH SHH SMAD4 SMAD4 DMRT3 DMRT3 LBX1 LBX1 WNT1 WNT1 NOTCH3 NOTCH3 GLI3 GLI3 OLIG3 OLIG3 HOXD10 HOXD10 HOXC10 HOXC10 ATOH1 ATOH1 TGFBR1 TGFBR1 EHMT2 EHMT2 IHH IHH CTNNB1 CTNNB1 DLX1 DLX1 ENSGGOP00000047870 ENSGGOP00000047870 CDC42 CDC42 RBPJ RBPJ NRG1 NRG1 FEV FEV PAX6 PAX6 PRRX1 PRRX1 NOTCH1 NOTCH1 GLI2 GLI2 ISL1 ISL1 FOXN4 FOXN4 G3R1I7_GORGO G3R1I7_GORGO NKX2-2 NKX2-2 GSX2 GSX2 G3QXA1_GORGO G3QXA1_GORGO GATA2 GATA2 DLL1 DLL1 ASCL1 ASCL1 MNX1 MNX1 DLX2 DLX2 GSX1 GSX1 EYA1 EYA1 ENSGGOP00000036799 ENSGGOP00000036799 DMRTA2 DMRTA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000032627Uncharacterized protein. (118 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
ISL2ISL LIM homeobox 2. (359 aa)
G3S9R1_GORGONK2 homeobox 1. (333 aa)
FEZF2Uncharacterized protein. (286 aa)
ENSGGOP00000024523annotation not available (408 aa)
ZNF521Zinc finger protein 521. (1311 aa)
MYT1LMyelin transcription factor 1 like. (1186 aa)
G3RTH8_GORGOPOU domain protein. (259 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
TBR1T-box brain transcription factor 1. (682 aa)
G3RPS4_GORGOUncharacterized protein. (241 aa)
SOX9SRY-box transcription factor 9. (509 aa)
GBX1Homeobox domain-containing protein. (309 aa)
PROX1Prospero homeobox 1. (737 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
DBX1Developing brain homeobox 1. (344 aa)
LHX3LIM homeobox 3. (400 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (472 aa)
LBX1Ladybird homeobox 1. (281 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
NOTCH3Notch receptor 3. (2317 aa)
GLI3GLI family zinc finger 3. (1580 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
HOXD10Homeobox D10. (340 aa)
HOXC10Homeobox C10. (342 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1267 aa)
IHHHH_signal domain-containing protein. (113 aa)
CTNNB1Catenin beta 1. (781 aa)
DLX1Distal-less homeobox 1. (255 aa)
ENSGGOP00000047870TPR_REGION domain-containing protein. (251 aa)
CDC42Cell division cycle 42. (191 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
NRG1Neuregulin 1. (713 aa)
FEVFEV transcription factor, ETS family member. (238 aa)
PAX6Uncharacterized protein. (475 aa)
PRRX1Paired related homeobox 1. (245 aa)
NOTCH1Uncharacterized protein. (1606 aa)
GLI2GLI family zinc finger 2. (1537 aa)
ISL1ISL LIM homeobox 1. (351 aa)
FOXN4Forkhead box N4. (517 aa)
G3R1I7_GORGOElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
NKX2-2NK2 homeobox 2. (273 aa)
GSX2GS homeobox 2. (304 aa)
G3QXA1_GORGODelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1199 aa)
GATA2GATA binding protein 2. (480 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (234 aa)
MNX1Homeobox domain-containing protein. (188 aa)
DLX2Distal-less homeobox 2. (328 aa)
GSX1GS homeobox 1. (264 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
ENSGGOP00000036799Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa)
DMRTA2DM domain-containing protein. (506 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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