(17 nodes) CARD domain binding network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOD2	Nucleotide binding oligomerization domain containing 2. (1040 aa)
	CARD8	Caspase recruitment domain family member 8. (522 aa)
	CARD16	Caspase recruitment domain family member 16. (197 aa)
	CARD18	Caspase recruitment domain family member 18. (90 aa)
	G3R3U7_GORGO	Mitochondrial antiviral signaling protein. (481 aa)
	CARD19	Caspase recruitment domain family member 19. (183 aa)
	IRGM	Immunity related GTPase M. (181 aa)
	CARD14	Caspase recruitment domain family member 14. (1004 aa)
	G3S2A2_GORGO	Caspase recruitment domain family member 10. (1028 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	ENSGGOP00000032091	Caspase 4; Belongs to the peptidase C14A family. (377 aa)
	ENSGGOP00000045267	Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
	ENSGGOP00000046758	Caspase 1; Belongs to the peptidase C14A family. (404 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	ENSGGOP00000048129	Caspase recruitment domain family member 9. (536 aa)
	BCL10	CARD domain-containing protein. (316 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL10	CARD11	ENSGGOP00000051225	ENSGGOP00000046946	CARD domain-containing protein.	Caspase recruitment domain family member 11.	0.999
BCL10	CARD14	ENSGGOP00000051225	ENSGGOP00000020122	CARD domain-containing protein.	Caspase recruitment domain family member 14.	0.864
BCL10	CARD19	ENSGGOP00000051225	ENSGGOP00000016382	CARD domain-containing protein.	Caspase recruitment domain family member 19.	0.483
BCL10	ENSGGOP00000048129	ENSGGOP00000051225	ENSGGOP00000048129	CARD domain-containing protein.	Caspase recruitment domain family member 9.	0.994
BCL10	G3R3U7_GORGO	ENSGGOP00000051225	ENSGGOP00000009929	CARD domain-containing protein.	Mitochondrial antiviral signaling protein.	0.526
BCL10	G3S2A2_GORGO	ENSGGOP00000051225	ENSGGOP00000022200	CARD domain-containing protein.	Caspase recruitment domain family member 10.	0.959
BCL10	NOD1	ENSGGOP00000051225	ENSGGOP00000022426	CARD domain-containing protein.	Nucleotide binding oligomerization domain containing 1.	0.479
BCL10	NOD2	ENSGGOP00000051225	ENSGGOP00000010525	CARD domain-containing protein.	Nucleotide binding oligomerization domain containing 2.	0.482
BCL10	RIPK2	ENSGGOP00000051225	ENSGGOP00000010569	CARD domain-containing protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.542
CARD11	BCL10	ENSGGOP00000046946	ENSGGOP00000051225	Caspase recruitment domain family member 11.	CARD domain-containing protein.	0.999
CARD11	CARD14	ENSGGOP00000046946	ENSGGOP00000020122	Caspase recruitment domain family member 11.	Caspase recruitment domain family member 14.	0.908
CARD11	ENSGGOP00000048129	ENSGGOP00000046946	ENSGGOP00000048129	Caspase recruitment domain family member 11.	Caspase recruitment domain family member 9.	0.710
CARD11	NOD2	ENSGGOP00000046946	ENSGGOP00000010525	Caspase recruitment domain family member 11.	Nucleotide binding oligomerization domain containing 2.	0.416
CARD11	RIPK2	ENSGGOP00000046946	ENSGGOP00000010569	Caspase recruitment domain family member 11.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.542
CARD14	BCL10	ENSGGOP00000020122	ENSGGOP00000051225	Caspase recruitment domain family member 14.	CARD domain-containing protein.	0.864
CARD14	CARD11	ENSGGOP00000020122	ENSGGOP00000046946	Caspase recruitment domain family member 14.	Caspase recruitment domain family member 11.	0.908
CARD14	ENSGGOP00000048129	ENSGGOP00000020122	ENSGGOP00000048129	Caspase recruitment domain family member 14.	Caspase recruitment domain family member 9.	0.462
CARD14	G3S2A2_GORGO	ENSGGOP00000020122	ENSGGOP00000022200	Caspase recruitment domain family member 14.	Caspase recruitment domain family member 10.	0.445
CARD14	NOD2	ENSGGOP00000020122	ENSGGOP00000010525	Caspase recruitment domain family member 14.	Nucleotide binding oligomerization domain containing 2.	0.578
CARD16	CARD18	ENSGGOP00000002111	ENSGGOP00000003060	Caspase recruitment domain family member 16.	Caspase recruitment domain family member 18.	0.921