114 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3QCX1_GORGO	Casein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
	HAUS3	HAUS augmin like complex subunit 3. (603 aa)
	NDC80	NDC80 kinetochore complex component. (642 aa)
	FBXO5	F-box protein 5. (447 aa)
	RACGAP1	Rac GTPase activating protein 1. (632 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa)
	STAG2	Stromal antigen 2. (1268 aa)
	FLNA	Filamin A. (2647 aa)
	NEK2	NIMA related kinase 2. (445 aa)
	ABRAXAS1	Abraxas 1, BRCA1 A complex subunit. (409 aa)
	CCDC69	Coiled-coil domain containing 69. (296 aa)
	RPS3	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	STARD9	StAR related lipid transfer domain containing 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (4595 aa)
	G3QW19_GORGO	Uncharacterized protein. (423 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	CDCA8	Cell division cycle associated 8. (280 aa)
	TOGARAM2	TOG array regulator of axonemal microtubules 2. (1019 aa)
	HAUS7	HAUS augmin like complex subunit 7. (368 aa)
	AURKC	Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
	KPNB1	Karyopherin subunit beta 1. (876 aa)
	HAUS8	HAUS augmin like complex subunit 8. (409 aa)
	CDC20	Cell division cycle 20. (499 aa)
	G3R4R4_GORGO	Uncharacterized protein. (269 aa)
	BCCIP	BRCA2 and CDKN1A interacting protein. (342 aa)
	G3R699_GORGO	Uncharacterized protein. (332 aa)
	TASOR	Transcription activation suppressor. (1610 aa)
	G3R6Z2_GORGO	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (770 aa)
	G3R798_GORGO	Uncharacterized protein. (464 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1327 aa)
	G3R860_GORGO	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1022 aa)
	KIF3B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
	RHOA	Uncharacterized protein. (179 aa)
	G3RBT3_GORGO	Uncharacterized protein. (1516 aa)
	ABRAXAS2	Abraxas 2, BRISC complex subunit. (415 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	TUBGCP2	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (902 aa)
	LZTS2	Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
	WRAP73	WD repeat containing, antisense to TP73. (460 aa)
	G3RIC2_GORGO	Aladin WD repeat nucleoporin. (546 aa)
	CCDC155	Coiled-coil domain containing 155. (562 aa)
	KIFC2	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (789 aa)
	MLH1	MutL homolog 1. (756 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	TUBB1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	SEPTIN1	Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
	MYBL2	MYB proto-oncogene like 2. (700 aa)
	G3RNT3_GORGO	KH type-2 domain-containing protein. (250 aa)
	CEP192	Centrosomal protein 192. (2537 aa)
	G3RP17_GORGO	Structural maintenance of chromosomes protein. (1175 aa)
	GOLGA2	Golgin A2. (995 aa)
	G3RPS1_GORGO	WD_REPEATS_REGION domain-containing protein. (457 aa)
	G3RQY5_GORGO	Uncharacterized protein. (134 aa)
	KIF4A	Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1232 aa)
	MAPRE2	Microtubule associated protein RP/EB family member 2. (327 aa)
	MAP10	Microtubule associated protein 10. (1043 aa)
	PRC1	Protein regulator of cytokinesis 1. (620 aa)
	MAPRE1	Uncharacterized protein. (268 aa)
	ASPM	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3476 aa)
	TUBB	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	G3SCX4_GORGO	TPX2 microtubule nucleation factor. (697 aa)
	G3SD31_GORGO	Uncharacterized protein. (720 aa)
	G3SDK2_GORGO	Uncharacterized protein. (434 aa)
	PIBF1	Progesterone immunomodulatory binding factor 1. (757 aa)
	SAC3D1	SAC3 domain containing 1. (349 aa)
	HAUS6	HAUS augmin like complex subunit 6. (955 aa)
	TUBGCP4	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
	ENSGGOP00000030123	HAUS augmin like complex subunit 2. (235 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (368 aa)
	ENSGGOP00000031306	Uncharacterized protein. (92 aa)
	MZT1	Mitotic spindle organizing protein 1. (78 aa)
	ENSGGOP00000034961	annotation not available (92 aa)
	TUBGCP6	Tubulin gamma complex associated protein 6. (1792 aa)
	ENSGGOP00000035259	Structural maintenance of chromosomes 1A. (1096 aa)
	ENSGGOP00000035698	Uncharacterized protein. (301 aa)
	ENSGGOP00000035777	Baculoviral IAP repeat containing 5. (165 aa)
	ENSGGOP00000036466	Checkpoint kinase 2. (529 aa)
	ENSGGOP00000037457	NIMA related kinase 6. (373 aa)
	WASHC5	Uncharacterized protein. (206 aa)
	STAG1	Stromal antigen 1. (1258 aa)
	HAUS1	HAUS augmin like complex subunit 1. (278 aa)
	ENSGGOP00000038576	Centrosomal protein 63. (703 aa)
	ENSGGOP00000038823	Nuclear receptor corepressor 1. (2386 aa)
	ENSGGOP00000039304	KH type-2 domain-containing protein. (116 aa)
	ENSGGOP00000041427	Cytoplasmic linker associated protein 1. (1538 aa)
	MAPRE3	Microtubule associated protein RP/EB family member 3. (281 aa)
	INCENP	Inner centromere protein. (903 aa)
	MISP	Mitotic spindle positioning. (679 aa)
	ENSGGOP00000042635	Calponin-homology (CH) domain-containing protein. (252 aa)
	ENSGGOP00000043386	Uncharacterized protein. (1478 aa)
	KIF2A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (734 aa)
	LSM14A	Uncharacterized protein. (488 aa)
	ENSGGOP00000043986	Uncharacterized protein. (407 aa)
	HAUS5	HAUS augmin like complex subunit 5. (633 aa)
	ENSGGOP00000044691	Uncharacterized protein. (141 aa)
	ENSGGOP00000044919	Uncharacterized protein. (125 aa)
	ENSGGOP00000045096	KH type-2 domain-containing protein. (245 aa)
	ZCWPW2	Zinc finger CW-type and PWWP domain containing 2. (356 aa)
	KIFC1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (754 aa)
	ENSGGOP00000046457	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (439 aa)
	ZNF207	Zinc finger protein 207. (497 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2115 aa)
	NEK7	NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
	ENSGGOP00000048713	Uncharacterized protein. (227 aa)
	ENSGGOP00000048960	Uncharacterized protein. (156 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1369 aa)
	ENSGGOP00000049876	annotation not available (227 aa)
	TOGARAM1	TOG array regulator of axonemal microtubules 1. (1773 aa)
	TUBGCP5	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1014 aa)
	ENSGGOP00000050644	Ribosomal_S3_C domain-containing protein. (100 aa)
	ENSGGOP00000050659	Uncharacterized protein; Belongs to the cyclin family. (347 aa)
	ENSGGOP00000051819	Protein kinase domain-containing protein. (421 aa)
	ENSGGOP00000051951	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (246 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABRAXAS1	ENSGGOP00000036466	ENSGGOP00000005699	ENSGGOP00000036466	Abraxas 1, BRCA1 A complex subunit.	Checkpoint kinase 2.	0.640
ARHGEF10	RHOA	ENSGGOP00000049550	ENSGGOP00000012527	Rho guanine nucleotide exchange factor 10.	Uncharacterized protein.	0.454
ASPM	AURKA	ENSGGOP00000024559	ENSGGOP00000007041	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Aurora kinase A; Belongs to the protein kinase superfamily.	0.730
ASPM	AURKB	ENSGGOP00000024559	ENSGGOP00000002820	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Aurora kinase B; Belongs to the protein kinase superfamily.	0.781
ASPM	AURKC	ENSGGOP00000024559	ENSGGOP00000007820	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Aurora kinase C; Belongs to the protein kinase superfamily.	0.647
ASPM	CCNB2	ENSGGOP00000024559	ENSGGOP00000007479	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Cyclin B2; Belongs to the cyclin family.	0.899
ASPM	CDC20	ENSGGOP00000024559	ENSGGOP00000010165	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Cell division cycle 20.	0.844
ASPM	CDCA8	ENSGGOP00000024559	ENSGGOP00000007551	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Cell division cycle associated 8.	0.801
ASPM	ENSGGOP00000035777	ENSGGOP00000024559	ENSGGOP00000035777	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Baculoviral IAP repeat containing 5.	0.847
ASPM	ENSGGOP00000038576	ENSGGOP00000024559	ENSGGOP00000038576	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Centrosomal protein 63.	0.643
ASPM	ENSGGOP00000048713	ENSGGOP00000024559	ENSGGOP00000048713	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Uncharacterized protein.	0.801
ASPM	ENSGGOP00000049876	ENSGGOP00000024559	ENSGGOP00000049876	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	annotation not available	0.801
ASPM	ENSGGOP00000050659	ENSGGOP00000024559	ENSGGOP00000050659	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Uncharacterized protein; Belongs to the cyclin family.	0.573
ASPM	ENSGGOP00000051819	ENSGGOP00000024559	ENSGGOP00000051819	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Protein kinase domain-containing protein.	0.818
ASPM	FBXO5	ENSGGOP00000024559	ENSGGOP00000001583	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	F-box protein 5.	0.426
ASPM	G3R860_GORGO	ENSGGOP00000024559	ENSGGOP00000011560	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.931
ASPM	G3RPS1_GORGO	ENSGGOP00000024559	ENSGGOP00000017791	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	WD_REPEATS_REGION domain-containing protein.	0.844
ASPM	G3SCX4_GORGO	ENSGGOP00000024559	ENSGGOP00000025952	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	TPX2 microtubule nucleation factor.	0.446
ASPM	INCENP	ENSGGOP00000024559	ENSGGOP00000042461	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Inner centromere protein.	0.607
ASPM	KIF23	ENSGGOP00000024559	ENSGGOP00000003903	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.922