STRINGSTRING
GBP3 GBP3 ITGAX ITGAX TRIM5 TRIM5 PLA2G10 PLA2G10 NT5C3A NT5C3A G3S3V1_GORGO G3S3V1_GORGO ENSGGOP00000033311 ENSGGOP00000033311 POLR3A POLR3A IFIT1B IFIT1B IFNK IFNK AKAP1 AKAP1 IFIT1 IFIT1 UNC93B1 UNC93B1 DDX58 DDX58 CD40 CD40 EIF2AK4 EIF2AK4 G3S872_GORGO G3S872_GORGO TBK1 TBK1 RNF185 RNF185 G3BP1 G3BP1 ADAR ADAR ENSGGOP00000025150 ENSGGOP00000025150 CGAS CGAS SHFL SHFL G3SE49_GORGO G3SE49_GORGO G3SEX1_GORGO G3SEX1_GORGO OAS1 OAS1 STAT1 STAT1 BPIFA1 BPIFA1 TLR3 TLR3 RNASE6 RNASE6 RELA RELA MARCHF2 MARCHF2 UNC13D UNC13D ZNF175 ZNF175 SLFN11 SLFN11 DHX36 DHX36 ENSGGOP00000028950 ENSGGOP00000028950 ENSGGOP00000029367 ENSGGOP00000029367 ABCC9 ABCC9 NDUFAF4 NDUFAF4 IFIT3 IFIT3 LYST LYST ENSGGOP00000032880 ENSGGOP00000032880 APOBEC3G APOBEC3G NMB NMB IFNA2 IFNA2 G3S132_GORGO G3S132_GORGO TRIM41 TRIM41 PHB PHB BCL2L1 BCL2L1 TLR7 TLR7 FADD FADD IKBKE IKBKE RNASEL RNASEL G3RV54_GORGO G3RV54_GORGO APOBEC3C APOBEC3C PLSCR1 PLSCR1 EIF2AK2 EIF2AK2 ELMOD2 ELMOD2 DDX50 DDX50 CNOT7 CNOT7 G3RSJ4_GORGO G3RSJ4_GORGO IL6 IL6 IFITM2 IFITM2 G3RRI7_GORGO G3RRI7_GORGO AZI2 AZI2 TRIM32 TRIM32 TRIM22 TRIM22 G3RPN5_GORGO G3RPN5_GORGO G3RPM5_GORGO G3RPM5_GORGO TRIM52 TRIM52 EXOC1 EXOC1 IFNB1 IFNB1 PYCARD PYCARD GPAM GPAM AGBL5 AGBL5 TRIM11 TRIM11 DHX15 DHX15 IRF2 IRF2 ATG16L1 ATG16L1 TRIM15 TRIM15 STING1 STING1 IRF9 IRF9 DTX3L DTX3L PARP9 PARP9 IFIH1 IFIH1 TRIM27 TRIM27 G3RID2_GORGO G3RID2_GORGO IFNE IFNE SKP2 SKP2 GBP1 GBP1 SERINC3 SERINC3 G3RH36_GORGO G3RH36_GORGO BST2 BST2 G3RG63_GORGO G3RG63_GORGO DDX60L DDX60L BNIP3 BNIP3 SLFN13 SLFN13 IRF1 IRF1 G3RD21_GORGO G3RD21_GORGO IFI44L IFI44L MID2 MID2 TRIM28 TRIM28 ADARB1 ADARB1 G3RAN6_GORGO G3RAN6_GORGO PCBP2 PCBP2 DDX1 DDX1 TLR8 TLR8 IL10RB IL10RB USP27X USP27X OASL OASL G3R8Q7_GORGO G3R8Q7_GORGO G3R8Q5_GORGO G3R8Q5_GORGO TRIM25 TRIM25 POLR3F POLR3F NLRP1 NLRP1 PQBP1 PQBP1 SAMHD1 SAMHD1 ZBP1 ZBP1 HERC5 HERC5 RSAD2 RSAD2 TRIM35 TRIM35 CXCL10 CXCL10 IFIT5 IFIT5 EXOSC4 EXOSC4 ISG20 ISG20 G3R3U7_GORGO G3R3U7_GORGO SENP7 SENP7 NLRC5 NLRC5 G3R2M9_GORGO G3R2M9_GORGO ZC3H12A ZC3H12A KCNJ8 KCNJ8 ZNFX1 ZNFX1 POLR3K POLR3K ZDHHC1 ZDHHC1 G3QZC8_GORGO G3QZC8_GORGO TRIM26 TRIM26 DDX17 DDX17 OAS2 OAS2 OAS3 OAS3 IL21 IL21 VAPB VAPB GBP7 GBP7 IFNL2 IFNL2 ABCF3 ABCF3 ARMC5 ARMC5 POLR3D POLR3D POLR3C POLR3C ITCH ITCH G3QW36_GORGO G3QW36_GORGO HYAL2 HYAL2 F2RL1 F2RL1 IFI27 IFI27 G3QV16_GORGO G3QV16_GORGO G3QUW7_GORGO G3QUW7_GORGO TRIM21 TRIM21 TREX1 TREX1 G3QTI0_GORGO G3QTI0_GORGO AIM2 AIM2 IFI16 IFI16 CLPB CLPB IFNG IFNG RNF135 RNF135 DHX58 DHX58 TTC4 TTC4 RNASE2 RNASE2 DDX21 DDX21 NLRP3 NLRP3 CD207 CD207 RIPK3 RIPK3 CXCL9 CXCL9 MAP3K14 MAP3K14 DEFA1B DEFA1B IL12B IL12B ATAD3A ATAD3A PHB2 PHB2 TRAF3 TRAF3 ILF3 ILF3 TRIM8 TRIM8 MYD88 MYD88 ATG7 ATG7 IFITM1 IFITM1 G3QLG8_GORGO G3QLG8_GORGO PDE12 PDE12 TLR2 TLR2 SPON2 SPON2 TANK TANK PRF1 PRF1 IL23A IL23A TRIM13 TRIM13 BECN1 BECN1 MX1 MX1 MX2 MX2 CXADR CXADR G3QGC7_GORGO G3QGC7_GORGO NCBP1 NCBP1 DNAJC3 DNAJC3 RTP4 RTP4 G3QF49_GORGO G3QF49_GORGO NMBR NMBR BCL2 BCL2 IFI6 IFI6 OPRK1 OPRK1 G3QEF0_GORGO G3QEF0_GORGO TRIM56 TRIM56 CARD8 CARD8 FCN3 FCN3 IRF5 IRF5 MLKL MLKL ENSGGOP00000034709 ENSGGOP00000034709 ENSGGOP00000035108 ENSGGOP00000035108 ENSGGOP00000035319 ENSGGOP00000035319 ENSGGOP00000035522 ENSGGOP00000035522 ENSGGOP00000035654 ENSGGOP00000035654 RAB2B RAB2B ENSGGOP00000036689 ENSGGOP00000036689 RIOK3 RIOK3 VAMP8 VAMP8 AGBL4 AGBL4 ENSGGOP00000038240 ENSGGOP00000038240 IFIT2 IFIT2 ENSGGOP00000038993 ENSGGOP00000038993 ENSGGOP00000039098 ENSGGOP00000039098 MBL2 MBL2 SERINC5 SERINC5 ENSGGOP00000040743 ENSGGOP00000040743 SETD2 SETD2 IL33 IL33 ENSGGOP00000042695 ENSGGOP00000042695 ENSGGOP00000043090 ENSGGOP00000043090 DDIT4 DDIT4 LSM14A LSM14A ENSGGOP00000043564 ENSGGOP00000043564 POLR3B POLR3B IRF7 IRF7 ENSGGOP00000044054 ENSGGOP00000044054 ENSGGOP00000044168 ENSGGOP00000044168 CRCP CRCP MOV10 MOV10 IFNA13 IFNA13 ENSGGOP00000045267 ENSGGOP00000045267 NLRP6 NLRP6 ENSGGOP00000045725 ENSGGOP00000045725 IFNLR1 IFNLR1 POLR3G POLR3G ENSGGOP00000046758 ENSGGOP00000046758 POLR3E POLR3E BNIP3L BNIP3L FAM71E1 FAM71E1 ENSGGOP00000048129 ENSGGOP00000048129 POLR3H POLR3H IFNAR2 IFNAR2 ACOD1 ACOD1 AICDA AICDA ENSGGOP00000051931 ENSGGOP00000051931
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GBP3Guanylate binding protein 3. (597 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa)
PLA2G10Phospholipase A(2). (155 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa)
G3S3V1_GORGOHelicase C-terminal domain-containing protein. (318 aa)
ENSGGOP00000033311Uncharacterized protein. (124 aa)
POLR3ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1387 aa)
IFIT1BInterferon induced protein with tetratricopeptide repeats 1B. (473 aa)
IFNKInterferon kappa. (207 aa)
AKAP1A-kinase anchoring protein 1. (903 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (478 aa)
UNC93B1Uncharacterized protein. (407 aa)
DDX58DExD/H-box helicase 58. (925 aa)
CD40CD40 molecule. (277 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
G3S872_GORGOUncharacterized protein. (132 aa)
TBK1TANK binding kinase 1. (729 aa)
RNF185Ring finger protein 185. (192 aa)
G3BP1G3BP stress granule assembly factor 1. (466 aa)
ADARAdenosine deaminase RNA specific. (1229 aa)
ENSGGOP00000025150annotation not available (245 aa)
CGASCyclic GMP-AMP synthase. (447 aa)
SHFLShiftless antiviral inhibitor of ribosomal frameshifting. (291 aa)
G3SE49_GORGONLR family pyrin domain containing 9. (934 aa)
G3SEX1_GORGOUncharacterized protein. (134 aa)
OAS12'-5'-oligoadenylate synthetase 1. (414 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
BPIFA1BPI fold containing family A member 1. (256 aa)
TLR3Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (904 aa)
RNASE6Ribonuclease K6; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. (150 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
MARCHF2Membrane associated ring-CH-type finger 2. (246 aa)
UNC13DUnc-13 homolog D. (1090 aa)
ZNF175Zinc finger protein 175. (711 aa)
SLFN11Schlafen family member 11. (901 aa)
DHX36DEAH-box helicase 36. (1008 aa)
ENSGGOP00000028950Uncharacterized protein. (212 aa)
ENSGGOP00000029367Pyrin domain-containing protein. (110 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
NDUFAF4NADH:ubiquinone oxidoreductase complex assembly factor 4. (175 aa)
IFIT3Interferon induced protein with tetratricopeptide repeats 3. (490 aa)
LYSTLysosomal trafficking regulator. (3790 aa)
ENSGGOP00000032880Zinc finger CCHC-type containing 3. (328 aa)
APOBEC3GDNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...] (376 aa)
NMBUncharacterized protein. (121 aa)
IFNA2Interferon alpha 2. (170 aa)
G3S132_GORGOProhibitin. (230 aa)
TRIM41Tripartite motif containing 41. (612 aa)
PHBProhibitin. (272 aa)
BCL2L1BCL2 like 1. (233 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
RNASELRibonuclease L. (741 aa)
G3RV54_GORGOProtein tyrosine phosphatase receptor type C. (1306 aa)
APOBEC3CDNA dC->dU-editing enzyme APOBEC-3C; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity). (201 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa)
ELMOD2ELMO domain containing 2. (293 aa)
DDX50DExD-box helicase 50. (737 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
G3RSJ4_GORGOUncharacterized protein. (133 aa)
IL6Interleukin 6. (234 aa)
IFITM2Interferon induced transmembrane protein 2. (132 aa)
G3RRI7_GORGOUncharacterized protein. (102 aa)
AZI25-azacytidine induced 2. (392 aa)
TRIM32Tripartite motif containing 32. (653 aa)
TRIM22Tripartite motif containing 22. (498 aa)
G3RPN5_GORGOGB1/RHD3-type G domain-containing protein. (501 aa)
G3RPM5_GORGOPromyelocytic leukemia. (834 aa)
TRIM52Tripartite motif containing 52. (295 aa)
EXOC1Exocyst complex component 1. (894 aa)
IFNB1Interferon beta 1. (187 aa)
PYCARDPYD and CARD domain containing. (195 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (829 aa)
AGBL5ATP/GTP binding protein like 5. (886 aa)
TRIM11Tripartite motif containing 11. (468 aa)
DHX15DEAH-box helicase 15. (795 aa)
IRF2Interferon regulatory factor. (349 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
TRIM15Tripartite motif containing 15. (465 aa)
STING1Transmembrane protein 173. (379 aa)
IRF9Interferon regulatory factor 9. (392 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (740 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (819 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
TRIM27Tripartite motif containing 27. (513 aa)
G3RID2_GORGOTIR domain-containing protein. (1033 aa)
IFNEInterferon epsilon. (208 aa)
SKP2S-phase kinase associated protein 2. (425 aa)
GBP1Guanylate binding protein 1. (592 aa)
SERINC3Serine incorporator 3. (473 aa)
G3RH36_GORGOInterferon lambda 1. (200 aa)
BST2Bone marrow stromal antigen 2. (185 aa)
G3RG63_GORGOISG15 ubiquitin like modifier. (165 aa)
DDX60LDExD/H-box 60 like. (1715 aa)
BNIP3Uncharacterized protein. (194 aa)
SLFN13Schlafen family member 13. (897 aa)
IRF1Interferon regulatory factor. (325 aa)
G3RD21_GORGOApolipoprotein B mRNA editing enzyme catalytic subunit 3F. (373 aa)
IFI44LInterferon induced protein 44 like. (452 aa)
MID2Midline 2. (735 aa)
TRIM28Tripartite motif containing 28. (701 aa)
ADARB1Adenosine deaminase RNA specific B1. (741 aa)
G3RAN6_GORGODExD/H-box helicase 60. (1610 aa)
PCBP2Poly(rC) binding protein 2. (366 aa)
DDX1DEAD-box helicase 1. (740 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1059 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
OASL2'-5'-oligoadenylate synthetase like. (514 aa)
G3R8Q7_GORGOInterferon omega 1. (195 aa)
G3R8Q5_GORGOUncharacterized protein. (170 aa)
TRIM25Tripartite motif containing 25. (630 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
NLRP1NLR family pyrin domain containing 1. (1471 aa)
PQBP1Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] (265 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (626 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
HERC5HECT and RLD domain containing E3 ubiquitin protein ligase 5. (1035 aa)
RSAD2Elp3 domain-containing protein. (361 aa)
TRIM35B30.2/SPRY domain-containing protein. (282 aa)
CXCL10C-X-C motif chemokine. (98 aa)
IFIT5Interferon induced protein with tetratricopeptide repeats 5. (482 aa)
EXOSC4Uncharacterized protein. (245 aa)
ISG20Interferon stimulated exonuclease gene 20. (181 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
SENP7SUMO specific peptidase 7. (1050 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
G3R2M9_GORGOProhibitin. (194 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1918 aa)
POLR3KDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
ZDHHC1Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (490 aa)
G3QZC8_GORGOExosome component 5. (235 aa)
TRIM26Tripartite motif containing 26. (542 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (735 aa)
OAS22'-5'-oligoadenylate synthetase 2. (687 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1087 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
VAPBVAMP associated protein B and C. (243 aa)
GBP7Guanylate binding protein 7. (638 aa)
IFNL2Interferon lambda 2. (200 aa)
ABCF3ATP binding cassette subfamily F member 3. (709 aa)
ARMC5Armadillo repeat containing 5. (1030 aa)
POLR3DRNA polymerase III subunit D. (398 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
ITCHE3 ubiquitin-protein ligase. (903 aa)
G3QW36_GORGOUncharacterized protein. (652 aa)
HYAL2Hyaluronidase. (473 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
IFI27Interferon alpha inducible protein 27. (122 aa)
G3QV16_GORGOApolipoprotein B mRNA editing enzyme catalytic subunit 3B. (382 aa)
G3QUW7_GORGOTIR domain-containing adapter molecule 1. (563 aa)
TRIM21Tripartite motif containing 21. (475 aa)
TREX1Three prime repair exonuclease 1. (369 aa)
G3QTI0_GORGOSignal transducer and activator of transcription. (853 aa)
AIM2Absent in melanoma 2. (343 aa)
IFI16Interferon gamma inducible protein 16. (785 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
RNF135Ring finger protein 135. (372 aa)
DHX58DExH-box helicase 58. (678 aa)
TTC4Tetratricopeptide repeat domain 4. (387 aa)
RNASE2Non-secretory ribonuclease; This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Possesses a wide variety of biological activities. (161 aa)
DDX21DExD-box helicase 21. (783 aa)
NLRP3NLR family pyrin domain containing 3. (1028 aa)
CD207CD207 molecule. (328 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
CXCL9C-X-C motif chemokine. (125 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
DEFA1BDEFENSIN domain-containing protein. (94 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
ATAD3AATPase family AAA domain containing 3A. (639 aa)
PHB2Prohibitin. (299 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
ILF3Interleukin enhancer binding factor 3. (898 aa)
TRIM8Tripartite motif containing 8. (551 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
IFITM1Interferon induced transmembrane protein 1. (125 aa)
G3QLG8_GORGOUncharacterized protein. (118 aa)
PDE12Phosphodiesterase 12. (609 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa)
SPON2Spondin 2. (331 aa)
TANKTRAF family member associated NFKB activator. (425 aa)
PRF1Perforin 1. (555 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
TRIM13Tripartite motif containing 13. (410 aa)
BECN1Beclin 1. (450 aa)
MX1MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa)
MX2MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa)
CXADRCXADR Ig-like cell adhesion molecule. (352 aa)
G3QGC7_GORGOUncharacterized protein. (133 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
RTP4Receptor transporter protein 4. (246 aa)
G3QF49_GORGOAzurocidin 1. (251 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
IFI6Interferon alpha inducible protein 6. (130 aa)
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
G3QEF0_GORGOZinc finger CCCH-type antiviral protein 1. (1024 aa)
TRIM56Tripartite motif containing 56. (755 aa)
CARD8Caspase recruitment domain family member 8. (522 aa)
FCN3Ficolin 3. (299 aa)
IRF5Interferon regulatory factor 5. (499 aa)
MLKLUncharacterized protein. (178 aa)
ENSGGOP00000034709Uncharacterized protein. (192 aa)
ENSGGOP00000035108Uncharacterized protein. (284 aa)
ENSGGOP00000035319TPR_REGION domain-containing protein. (333 aa)
ENSGGOP00000035522Interferon alpha 1. (198 aa)
ENSGGOP00000035654Uncharacterized protein. (277 aa)
RAB2BRAB2B, member RAS oncogene family. (216 aa)
ENSGGOP00000036689RPOL9 domain-containing protein. (90 aa)
RIOK3RIO domain-containing protein. (311 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (113 aa)
AGBL4ATP/GTP binding protein like 4. (503 aa)
ENSGGOP00000038240Uncharacterized protein. (176 aa)
IFIT2Interferon induced protein with tetratricopeptide repeats 2. (472 aa)
ENSGGOP00000038993Helicase C-terminal domain-containing protein. (363 aa)
ENSGGOP00000039098Uncharacterized protein. (231 aa)
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (248 aa)
SERINC5Serine incorporator 5. (461 aa)
ENSGGOP00000040743NTF2 domain-containing protein. (390 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2564 aa)
IL33Interleukin 33. (270 aa)
ENSGGOP00000042695Uncharacterized protein. (164 aa)
ENSGGOP00000043090Prohibitin. (177 aa)
DDIT4DNA damage inducible transcript 4. (232 aa)
LSM14AUncharacterized protein. (488 aa)
ENSGGOP00000043564Interferon regulatory factor 3. (452 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
IRF7Interferon regulatory factor 7. (516 aa)
ENSGGOP00000044054Uncharacterized protein. (157 aa)
ENSGGOP00000044168Prohibitin. (258 aa)
CRCPCGRP receptor component. (148 aa)
MOV10Mov10 RISC complex RNA helicase. (1005 aa)
IFNA13Interferon alpha 13. (195 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
NLRP6Uncharacterized protein. (912 aa)
ENSGGOP00000045725Zinc finger MYND-type containing 11. (645 aa)
IFNLR1Interferon lambda receptor 1. (520 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
POLR3ERNA polymerase III subunit E. (708 aa)
BNIP3LBCL2 interacting protein 3 like. (199 aa)
FAM71E1Family with sequence similarity 71 member E1. (247 aa)
ENSGGOP00000048129Caspase recruitment domain family member 9. (536 aa)
POLR3HRNA polymerase III subunit H. (230 aa)
IFNAR2Uncharacterized protein. (519 aa)
ACOD1Aconitate decarboxylase 1. (481 aa)
AICDAActivation induced cytidine deaminase. (199 aa)
ENSGGOP00000051931Interferon gamma receptor 2. (356 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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