STRINGSTRING
CAV3 CAV3 CALM3 CALM3 G3QDC0_GORGO G3QDC0_GORGO G3QDF2_GORGO G3QDF2_GORGO CX3CL1 CX3CL1 BCL2 BCL2 SRI SRI SESTD1 SESTD1 REM1 REM1 G3QFE2_GORGO G3QFE2_GORGO SLC9A1 SLC9A1 FKBP1B FKBP1B G3QHC9_GORGO G3QHC9_GORGO RAMP3 RAMP3 G3QIB9_GORGO G3QIB9_GORGO VMP1 VMP1 CBARP CBARP ATP1B1 ATP1B1 CALM1 CALM1 CACNA1C CACNA1C JPH1 JPH1 CABP5 CABP5 CD4 CD4 DRD2 DRD2 PKD2 PKD2 PSEN2 PSEN2 LGALS3 LGALS3 WFS1 WFS1 CACNA1D CACNA1D G3QMP2_GORGO G3QMP2_GORGO G3QNS1_GORGO G3QNS1_GORGO CEMIP CEMIP TRPC3 TRPC3 CXCL9 CXCL9 G3QQ53_GORGO G3QQ53_GORGO G3QQC9_GORGO G3QQC9_GORGO GRAMD2A GRAMD2A GSTO1 GSTO1 IL16 IL16 G3QRP1_GORGO G3QRP1_GORGO ARRB2 ARRB2 G3QSH5_GORGO G3QSH5_GORGO EGF EGF G3QTR5_GORGO G3QTR5_GORGO C4orf3 C4orf3 PLA2G1B PLA2G1B JPH2 JPH2 PDE4B PDE4B F2 F2 TMC2 TMC2 GNAI2 GNAI2 HPCAL1 HPCAL1 G3QW36_GORGO G3QW36_GORGO TMEM38B TMEM38B PDGFRB PDGFRB CREB3 CREB3 INPP5K INPP5K G3QXA0_GORGO G3QXA0_GORGO F2RL3 F2RL3 ITGB3 ITGB3 PLCG1 PLCG1 THADA THADA FYN FYN TMEM38A TMEM38A LACRT LACRT SPINK1 SPINK1 G3QZC2_GORGO G3QZC2_GORGO LHCGR LHCGR ATP2A1 ATP2A1 HES1 HES1 RCVRN RCVRN PACSIN3 PACSIN3 ASPH ASPH FFAR1 FFAR1 TRPC6 TRPC6 G3R1M0_GORGO G3R1M0_GORGO KCNE2 KCNE2 P2RX5 P2RX5 P2RX2 P2RX2 CABP4 CABP4 HPCA HPCA PAWR PAWR CRACR2A CRACR2A G3R467_GORGO G3R467_GORGO BAX BAX FMR1 FMR1 F2R F2R CXCL10 CXCL10 ABL1 ABL1 STAC3 STAC3 VDAC1 VDAC1 TOR2A TOR2A TSPAN13 TSPAN13 G3R6H4_GORGO G3R6H4_GORGO PLPP4 PLPP4 RGS4 RGS4 SELENON SELENON THY1 THY1 UCN UCN NPSR1 NPSR1 PRKD1 PRKD1 SPG11 SPG11 PRKCE PRKCE GRM6 GRM6 CHD7 CHD7 LYN LYN G3RAA2_GORGO G3RAA2_GORGO ADORA2A ADORA2A CORO1A CORO1A CACNG1 CACNG1 G3RAK0_GORGO G3RAK0_GORGO RHOA RHOA NPPA NPPA GEM GEM CABP1 CABP1 G3RCB1_GORGO G3RCB1_GORGO STAC STAC FCRL3 FCRL3 STC2 STC2 C1H1orf226 C1H1orf226 G3RD62_GORGO G3RD62_GORGO G3RD86_GORGO G3RD86_GORGO CALCA CALCA PTPN6 PTPN6 ATP2B1 ATP2B1 G3RES3_GORGO G3RES3_GORGO CASQ1 CASQ1 G3RFB9_GORGO G3RFB9_GORGO CACNB3 CACNB3 DHRS7C DHRS7C PDGFB PDGFB PTK2B PTK2B REM2 REM2 G3RIH3_GORGO G3RIH3_GORGO TRIM27 TRIM27 G3RIZ8_GORGO G3RIZ8_GORGO CCL2 CCL2 UBQLN1 UBQLN1 CXCL12 CXCL12 HTT HTT VDR VDR PLP1 PLP1 ATG5 ATG5 MYLK MYLK CD19 CD19 NOS3 NOS3 NTSR1 NTSR1 CASQ2 CASQ2 PLA2G6 PLA2G6 ATP2C2 ATP2C2 SLC30A1 SLC30A1 AKAP6 AKAP6 TRPV3 TRPV3 G3RPM5_GORGO G3RPM5_GORGO G3RPR5_GORGO G3RPR5_GORGO PTGS2 PTGS2 G3RQF4_GORGO G3RQF4_GORGO BEST1 BEST1 CRACR2B CRACR2B IAPP IAPP G3RR23_GORGO G3RR23_GORGO G3RRC5_GORGO G3RRC5_GORGO BAK1 BAK1 HOMER3 HOMER3 G3RT65_GORGO G3RT65_GORGO G3RTQ0_GORGO G3RTQ0_GORGO CASR CASR CCL3 CCL3 G3RXV4_GORGO G3RXV4_GORGO G3RXW1_GORGO G3RXW1_GORGO JPH3 JPH3 JSRP1 JSRP1 CACNA1F CACNA1F CAV1 CAV1 JPH4 JPH4 ATP1A2 ATP1A2 P2RX1 P2RX1 ANK2 ANK2 CLIC2 CLIC2 METTL21C METTL21C EFHB EFHB G3S6B7_GORGO G3S6B7_GORGO ADRA2A ADRA2A PIK3CG PIK3CG TRPC1 TRPC1 G3S8D3_GORGO G3S8D3_GORGO TMC1 TMC1 APLNR APLNR AHNAK AHNAK PDPK1 PDPK1 RGN RGN G3SCJ7_GORGO G3SCJ7_GORGO CD33 CD33 TGFB1 TGFB1 GCG GCG AKAP5 AKAP5 G3SEV0_GORGO G3SEV0_GORGO NOS1 NOS1 HCRT HCRT PPP3CB PPP3CB STC1 STC1 SNCA SNCA SARAF SARAF G3SHM7_GORGO G3SHM7_GORGO LILRA5 LILRA5 G3SI79_GORGO G3SI79_GORGO CXCR3 CXCR3 PLCG2 PLCG2 ENSGGOP00000028898 ENSGGOP00000028898 R3HDM2 R3HDM2 STAC2 STAC2 MS4A1 MS4A1 CAMK2A CAMK2A CALCR CALCR ENSGGOP00000031130 ENSGGOP00000031130 ENSGGOP00000031235 ENSGGOP00000031235 ENSGGOP00000031578 ENSGGOP00000031578 ENSGGOP00000031606 ENSGGOP00000031606 ENSGGOP00000032040 ENSGGOP00000032040 ENSGGOP00000032522 ENSGGOP00000032522 ENSGGOP00000032712 ENSGGOP00000032712 PPP3CA PPP3CA CAMK2B CAMK2B ENSGGOP00000033982 ENSGGOP00000033982 CACNA2D1 CACNA2D1 PRNP PRNP ENSGGOP00000034427 ENSGGOP00000034427 EHD3 EHD3 ENSGGOP00000036219 ENSGGOP00000036219 CXCL11 CXCL11 ENSGGOP00000037329 ENSGGOP00000037329 DMD DMD ENSGGOP00000037657 ENSGGOP00000037657 PDE4D PDE4D UBASH3B UBASH3B NIPSNAP2 NIPSNAP2 PPP3R1 PPP3R1 ENSGGOP00000039905 ENSGGOP00000039905 HOMER2 HOMER2 P2RX3 P2RX3 DRD1 DRD1 YWHAE YWHAE ENSGGOP00000040681 ENSGGOP00000040681 ENSGGOP00000040850 ENSGGOP00000040850 CACNB4 CACNB4 ENSGGOP00000041843 ENSGGOP00000041843 ENSGGOP00000042059 ENSGGOP00000042059 TMBIM6 TMBIM6 SMIM6 SMIM6 ENSGGOP00000043662 ENSGGOP00000043662 ENSGGOP00000043921 ENSGGOP00000043921 ENSGGOP00000044572 ENSGGOP00000044572 CACNB1 CACNB1 ENSGGOP00000044877 ENSGGOP00000044877 ENSGGOP00000045245 ENSGGOP00000045245 ENSGGOP00000045869 ENSGGOP00000045869 RRAD RRAD CASK CASK WNK3 WNK3 ENSGGOP00000047330 ENSGGOP00000047330 EPO EPO STRIT1 STRIT1 MRLN MRLN ENSGGOP00000048104 ENSGGOP00000048104 CTNNB1 CTNNB1 ENSGGOP00000048996 ENSGGOP00000048996 STIM2 STIM2 PLN PLN SLN SLN CCR1 CCR1 HSPA2 HSPA2 HOMER1 HOMER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
G3QDC0_GORGOTriadin. (728 aa)
G3QDF2_GORGOTransient receptor potential cation channel subfamily V member 2. (630 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
SRISorcin. (198 aa)
SESTD1SEC14 and spectrin domain containing 1. (696 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
G3QFE2_GORGOG protein subunit beta 5. (394 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
G3QHC9_GORGOGlutamate ionotropic receptor NMDA type subunit 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (814 aa)
RAMP3Receptor activity modifying protein 3. (152 aa)
G3QIB9_GORGOOpioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CBARPCACN subunit beta associated regulatory protein. (454 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (247 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
CABP5Calcium binding protein 5. (173 aa)
CD4CD4 molecule. (458 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
LGALS3Galectin. (267 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
G3QMP2_GORGOProtein tyrosine phosphatase non-receptor type 22. (693 aa)
G3QNS1_GORGOErythrocyte membrane protein band 4.1. (864 aa)
CEMIPCell migration inducing hyaluronidase 1. (1361 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
CXCL9C-X-C motif chemokine. (125 aa)
G3QQ53_GORGOUncharacterized protein. (263 aa)
G3QQC9_GORGOGlucose-6-phosphate dehydrogenase. (561 aa)
GRAMD2AGRAM domain containing 2A. (354 aa)
GSTO1Glutathione S-transferase omega 1; Belongs to the GST superfamily. (241 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1331 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
ARRB2Arrestin beta 2. (409 aa)
G3QSH5_GORGOTyrosine-protein kinase. (1124 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
G3QTR5_GORGOCalcium/calmodulin dependent protein kinase II gamma. (534 aa)
C4orf3Chromosome 4 open reading frame 3. (199 aa)
PLA2G1BPhospholipase A(2). (148 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
PDE4BPhosphodiesterase. (736 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
TMC2Transmembrane channel-like protein. (906 aa)
GNAI2G protein subunit alpha i2. (355 aa)
HPCAL1Hippocalcin like 1. (193 aa)
G3QW36_GORGOUncharacterized protein. (652 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
G3QXA0_GORGOSCY domain-containing protein. (53 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (837 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
THADATHADA armadillo repeat containing. (1953 aa)
FYNTyrosine-protein kinase. (537 aa)
TMEM38ATransmembrane protein 38A. (257 aa)
LACRTLacritin. (137 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
G3QZC2_GORGOHistidine rich calcium binding protein. (692 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (795 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
RCVRNRecoverin. (200 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
G3R1M0_GORGOCalcium voltage-gated channel auxiliary subunit beta 2. (632 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (428 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (411 aa)
CABP4Calcium binding protein 4. (275 aa)
HPCAHippocalcin. (193 aa)
PAWRPro-apoptotic WT1 regulator. (341 aa)
CRACR2ACalcium release activated channel regulator 2A. (731 aa)
G3R467_GORGOTranslocator protein. (169 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
FMR1Fragile X mental retardation 1. (624 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CXCL10C-X-C motif chemokine. (98 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
VDAC1Voltage dependent anion channel 1. (289 aa)
TOR2ATorsin. (321 aa)
TSPAN13Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (204 aa)
G3R6H4_GORGOUncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (963 aa)
PLPP4Uncharacterized protein. (118 aa)
RGS4Regulator of G protein signaling 4. (302 aa)
SELENONSelenoprotein N. (495 aa)
THY1Thy-1 cell surface antigen. (161 aa)
UCNUrocortin. (124 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (393 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2414 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
GRM6Glutamate metabotropic receptor 6. (877 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
LYNTyrosine-protein kinase. (512 aa)
G3RAA2_GORGOProtein phosphatase 3 catalytic subunit gamma. (483 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
G3RAK0_GORGOHAP1 N-terminal domain-containing protein. (471 aa)
RHOAUncharacterized protein. (179 aa)
NPPANatriuretic peptide A. (153 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
CABP1Calcium binding protein 1. (370 aa)
G3RCB1_GORGOG_PROTEIN_RECEP_F1_2 domain-containing protein. (284 aa)
STACSH3 and cysteine rich domain. (402 aa)
FCRL3Fc receptor like 3. (741 aa)
STC2Stanniocalcin 2. (302 aa)
C1H1orf226Nitric oxide synthase 1 adaptor protein. (506 aa)
G3RD62_GORGOUncharacterized protein. (488 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
G3RES3_GORGOUncharacterized protein. (133 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
G3RFB9_GORGOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (487 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
G3RIH3_GORGOADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa)
TRIM27Tripartite motif containing 27. (513 aa)
G3RIZ8_GORGOBridging integrator 1. (593 aa)
CCL2C-C motif chemokine. (99 aa)
UBQLN1Ubiquilin 1. (589 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
HTTHuntingtin. (3071 aa)
VDRVitamin D receptor. (477 aa)
PLP1Proteolipid protein 1. (277 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MYLKMyosin light chain kinase. (1914 aa)
CD19CD19 molecule. (556 aa)
NOS3Nitric oxide synthase 3. (997 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa)
SLC30A1Uncharacterized protein. (410 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
G3RPM5_GORGOPromyelocytic leukemia. (834 aa)
G3RPR5_GORGOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
G3RQF4_GORGOLeukocyte immunoglobulin like receptor A2. (483 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa)
CRACR2BCalcium release activated channel regulator 2B. (400 aa)
IAPPIslet amyloid polypeptide. (89 aa)
G3RR23_GORGOUncharacterized protein. (210 aa)
G3RRC5_GORGOUncharacterized protein. (491 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
HOMER3Homer scaffold protein 3. (361 aa)
G3RT65_GORGOSphingosine kinase 2. (663 aa)
G3RTQ0_GORGOVoltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (228 aa)
CASRCalcium sensing receptor. (1078 aa)
CCL3C-C motif chemokine. (92 aa)
G3RXV4_GORGOUncharacterized protein. (345 aa)
G3RXW1_GORGOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (770 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (332 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ANK2Ankyrin 2. (3957 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
METTL21CMethyltransferase like 21C. (264 aa)
EFHBEF-hand domain family member B. (833 aa)
G3S6B7_GORGOPyrimidinergic receptor P2Y6. (328 aa)
ADRA2AAdrenoceptor alpha 2A. (465 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
G3S8D3_GORGOCalcium/calmodulin dependent protein kinase II delta. (533 aa)
TMC1Transmembrane channel-like protein. (760 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
AHNAKPDZ domain-containing protein. (5891 aa)
PDPK1Protein kinase domain-containing protein. (347 aa)
RGNRegucalcin. (299 aa)
G3SCJ7_GORGOCNX domain-containing protein. (249 aa)
CD33CD33 molecule. (364 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GCGGlucagon. (180 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
G3SEV0_GORGOUncharacterized protein; Belongs to the calmodulin family. (152 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
STC1Stanniocalcin 1. (247 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa)
SARAFStore-operated calcium entry associated regulatory factor. (340 aa)
G3SHM7_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa)
LILRA5Leukocyte immunoglobulin like receptor A5. (300 aa)
G3SI79_GORGOUncharacterized protein. (229 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSGGOP0000002889814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa)
R3HDM2R3H domain containing 2. (1034 aa)
STAC2SH3 and cysteine rich domain 2. (404 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
ENSGGOP00000031130Uncharacterized protein. (189 aa)
ENSGGOP00000031235Uncharacterized protein; Belongs to the calmodulin family. (129 aa)
ENSGGOP00000031578Rad60-SLD domain-containing protein. (84 aa)
ENSGGOP00000031606Stromal interaction molecule 1. (791 aa)
ENSGGOP00000032040Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ENSGGOP0000003252214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa)
ENSGGOP00000032712Uncharacterized protein. (264 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (644 aa)
ENSGGOP00000033982Uncharacterized protein. (256 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (253 aa)
ENSGGOP00000034427Calpain 3; Belongs to the peptidase C2 family. (821 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (553 aa)
ENSGGOP00000036219annotation not available (193 aa)
CXCL11C-X-C motif chemokine. (94 aa)
ENSGGOP00000037329R3H domain containing 1. (1101 aa)
DMDDystrophin. (3685 aa)
ENSGGOP00000037657Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PDE4DPhosphodiesterase. (748 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
NIPSNAP2Nipsnap homolog 2. (259 aa)
PPP3R1Uncharacterized protein. (189 aa)
ENSGGOP00000039905Uncharacterized protein. (142 aa)
HOMER2Homer scaffold protein 2. (356 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
ENSGGOP00000040681Uncharacterized protein; Belongs to the calmodulin family. (70 aa)
ENSGGOP00000040850Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
ENSGGOP00000041843G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ENSGGOP00000042059Ubiquitin-like domain-containing protein. (146 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (295 aa)
SMIM6Small integral membrane protein 6. (62 aa)
ENSGGOP00000043662Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
ENSGGOP00000043921P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
ENSGGOP00000044572Diaphanous related formin 1. (1242 aa)
CACNB1SH3 domain-containing protein. (119 aa)
ENSGGOP00000044877Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
ENSGGOP00000045245Ryanodine receptor 2. (4768 aa)
ENSGGOP00000045869Rad60-SLD domain-containing protein. (95 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (300 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
ENSGGOP00000047330Uncharacterized protein. (261 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
MRLNMyoregulin. (46 aa)
ENSGGOP00000048104annotation not available (264 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSGGOP00000048996Ig-like domain-containing protein. (180 aa)
STIM2Stromal interaction molecule 2. (842 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SLNSarcolipin. (31 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
HOMER1Homer scaffold protein 1. (366 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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