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CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) | ||||
G3QDC0_GORGO | Triadin. (728 aa) | ||||
G3QDF2_GORGO | Transient receptor potential cation channel subfamily V member 2. (630 aa) | ||||
CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
SRI | Sorcin. (198 aa) | ||||
SESTD1 | SEC14 and spectrin domain containing 1. (696 aa) | ||||
REM1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa) | ||||
G3QFE2_GORGO | G protein subunit beta 5. (394 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (95 aa) | ||||
G3QHC9_GORGO | Glutamate ionotropic receptor NMDA type subunit 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (814 aa) | ||||
RAMP3 | Receptor activity modifying protein 3. (152 aa) | ||||
G3QIB9_GORGO | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) | ||||
VMP1 | Vacuole membrane protein 1. (406 aa) | ||||
CBARP | CACN subunit beta associated regulatory protein. (454 aa) | ||||
ATP1B1 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (247 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (150 aa) | ||||
CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) | ||||
JPH1 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa) | ||||
CABP5 | Calcium binding protein 5. (173 aa) | ||||
CD4 | CD4 molecule. (458 aa) | ||||
DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa) | ||||
PKD2 | Polycystin 2, transient receptor potential cation channel. (968 aa) | ||||
PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa) | ||||
LGALS3 | Galectin. (267 aa) | ||||
WFS1 | Wolframin ER transmembrane glycoprotein. (890 aa) | ||||
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) | ||||
G3QMP2_GORGO | Protein tyrosine phosphatase non-receptor type 22. (693 aa) | ||||
G3QNS1_GORGO | Erythrocyte membrane protein band 4.1. (864 aa) | ||||
CEMIP | Cell migration inducing hyaluronidase 1. (1361 aa) | ||||
TRPC3 | Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa) | ||||
CXCL9 | C-X-C motif chemokine. (125 aa) | ||||
G3QQ53_GORGO | Uncharacterized protein. (263 aa) | ||||
G3QQC9_GORGO | Glucose-6-phosphate dehydrogenase. (561 aa) | ||||
GRAMD2A | GRAM domain containing 2A. (354 aa) | ||||
GSTO1 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. (241 aa) | ||||
IL16 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1331 aa) | ||||
G3QRP1_GORGO | Uncharacterized protein. (107 aa) | ||||
ARRB2 | Arrestin beta 2. (409 aa) | ||||
G3QSH5_GORGO | Tyrosine-protein kinase. (1124 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa) | ||||
G3QTR5_GORGO | Calcium/calmodulin dependent protein kinase II gamma. (534 aa) | ||||
C4orf3 | Chromosome 4 open reading frame 3. (199 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
JPH2 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa) | ||||
PDE4B | Phosphodiesterase. (736 aa) | ||||
F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa) | ||||
TMC2 | Transmembrane channel-like protein. (906 aa) | ||||
GNAI2 | G protein subunit alpha i2. (355 aa) | ||||
HPCAL1 | Hippocalcin like 1. (193 aa) | ||||
G3QW36_GORGO | Uncharacterized protein. (652 aa) | ||||
TMEM38B | Transmembrane protein 38B. (291 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
CREB3 | cAMP responsive element binding protein 3. (371 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (448 aa) | ||||
G3QXA0_GORGO | SCY domain-containing protein. (53 aa) | ||||
F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa) | ||||
ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (837 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
THADA | THADA armadillo repeat containing. (1953 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
TMEM38A | Transmembrane protein 38A. (257 aa) | ||||
LACRT | Lacritin. (137 aa) | ||||
SPINK1 | Serine peptidase inhibitor, Kazal type 1. (79 aa) | ||||
G3QZC2_GORGO | Histidine rich calcium binding protein. (692 aa) | ||||
LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa) | ||||
ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (795 aa) | ||||
HES1 | Hes family bHLH transcription factor 1. (280 aa) | ||||
RCVRN | Recoverin. (200 aa) | ||||
PACSIN3 | Protein kinase C and casein kinase substrate in neurons 3. (424 aa) | ||||
ASPH | Aspartate beta-hydroxylase. (762 aa) | ||||
FFAR1 | Free fatty acid receptor 1. (300 aa) | ||||
TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa) | ||||
G3R1M0_GORGO | Calcium voltage-gated channel auxiliary subunit beta 2. (632 aa) | ||||
KCNE2 | Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa) | ||||
P2RX5 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (428 aa) | ||||
P2RX2 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (411 aa) | ||||
CABP4 | Calcium binding protein 4. (275 aa) | ||||
HPCA | Hippocalcin. (193 aa) | ||||
PAWR | Pro-apoptotic WT1 regulator. (341 aa) | ||||
CRACR2A | Calcium release activated channel regulator 2A. (731 aa) | ||||
G3R467_GORGO | Translocator protein. (169 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (217 aa) | ||||
FMR1 | Fragile X mental retardation 1. (624 aa) | ||||
F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) | ||||
CXCL10 | C-X-C motif chemokine. (98 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1149 aa) | ||||
STAC3 | SH3 and cysteine rich domain 3. (364 aa) | ||||
VDAC1 | Voltage dependent anion channel 1. (289 aa) | ||||
TOR2A | Torsin. (321 aa) | ||||
TSPAN13 | Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (204 aa) | ||||
G3R6H4_GORGO | Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (963 aa) | ||||
PLPP4 | Uncharacterized protein. (118 aa) | ||||
RGS4 | Regulator of G protein signaling 4. (302 aa) | ||||
SELENON | Selenoprotein N. (495 aa) | ||||
THY1 | Thy-1 cell surface antigen. (161 aa) | ||||
UCN | Urocortin. (124 aa) | ||||
NPSR1 | Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (393 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa) | ||||
SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2414 aa) | ||||
PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) | ||||
GRM6 | Glutamate metabotropic receptor 6. (877 aa) | ||||
CHD7 | Chromodomain helicase DNA binding protein 7. (2997 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
G3RAA2_GORGO | Protein phosphatase 3 catalytic subunit gamma. (483 aa) | ||||
ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) | ||||
CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) | ||||
CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa) | ||||
G3RAK0_GORGO | HAP1 N-terminal domain-containing protein. (471 aa) | ||||
RHOA | Uncharacterized protein. (179 aa) | ||||
NPPA | Natriuretic peptide A. (153 aa) | ||||
GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa) | ||||
CABP1 | Calcium binding protein 1. (370 aa) | ||||
G3RCB1_GORGO | G_PROTEIN_RECEP_F1_2 domain-containing protein. (284 aa) | ||||
STAC | SH3 and cysteine rich domain. (402 aa) | ||||
FCRL3 | Fc receptor like 3. (741 aa) | ||||
STC2 | Stanniocalcin 2. (302 aa) | ||||
C1H1orf226 | Nitric oxide synthase 1 adaptor protein. (506 aa) | ||||
G3RD62_GORGO | Uncharacterized protein. (488 aa) | ||||
G3RD86_GORGO | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
CALCA | Calcitonin related polypeptide alpha. (141 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) | ||||
G3RES3_GORGO | Uncharacterized protein. (133 aa) | ||||
CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa) | ||||
G3RFB9_GORGO | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa) | ||||
CACNB3 | Calcium voltage-gated channel auxiliary subunit beta 3. (487 aa) | ||||
DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) | ||||
REM2 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa) | ||||
G3RIH3_GORGO | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) | ||||
TRIM27 | Tripartite motif containing 27. (513 aa) | ||||
G3RIZ8_GORGO | Bridging integrator 1. (593 aa) | ||||
CCL2 | C-C motif chemokine. (99 aa) | ||||
UBQLN1 | Ubiquilin 1. (589 aa) | ||||
CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) | ||||
HTT | Huntingtin. (3071 aa) | ||||
VDR | Vitamin D receptor. (477 aa) | ||||
PLP1 | Proteolipid protein 1. (277 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) | ||||
MYLK | Myosin light chain kinase. (1914 aa) | ||||
CD19 | CD19 molecule. (556 aa) | ||||
NOS3 | Nitric oxide synthase 3. (997 aa) | ||||
NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa) | ||||
CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa) | ||||
PLA2G6 | Phospholipase A2 group VI. (806 aa) | ||||
ATP2C2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa) | ||||
SLC30A1 | Uncharacterized protein. (410 aa) | ||||
AKAP6 | A-kinase anchoring protein 6. (2318 aa) | ||||
TRPV3 | Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa) | ||||
G3RPM5_GORGO | Promyelocytic leukemia. (834 aa) | ||||
G3RPR5_GORGO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
G3RQF4_GORGO | Leukocyte immunoglobulin like receptor A2. (483 aa) | ||||
BEST1 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa) | ||||
CRACR2B | Calcium release activated channel regulator 2B. (400 aa) | ||||
IAPP | Islet amyloid polypeptide. (89 aa) | ||||
G3RR23_GORGO | Uncharacterized protein. (210 aa) | ||||
G3RRC5_GORGO | Uncharacterized protein. (491 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
HOMER3 | Homer scaffold protein 3. (361 aa) | ||||
G3RT65_GORGO | Sphingosine kinase 2. (663 aa) | ||||
G3RTQ0_GORGO | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (228 aa) | ||||
CASR | Calcium sensing receptor. (1078 aa) | ||||
CCL3 | C-C motif chemokine. (92 aa) | ||||
G3RXV4_GORGO | Uncharacterized protein. (345 aa) | ||||
G3RXW1_GORGO | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa) | ||||
JPH3 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (770 aa) | ||||
JSRP1 | Junctional sarcoplasmic reticulum protein 1. (332 aa) | ||||
CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa) | ||||
JPH4 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa) | ||||
ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) | ||||
P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) | ||||
ANK2 | Ankyrin 2. (3957 aa) | ||||
CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa) | ||||
METTL21C | Methyltransferase like 21C. (264 aa) | ||||
EFHB | EF-hand domain family member B. (833 aa) | ||||
G3S6B7_GORGO | Pyrimidinergic receptor P2Y6. (328 aa) | ||||
ADRA2A | Adrenoceptor alpha 2A. (465 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa) | ||||
G3S8D3_GORGO | Calcium/calmodulin dependent protein kinase II delta. (533 aa) | ||||
TMC1 | Transmembrane channel-like protein. (760 aa) | ||||
APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) | ||||
AHNAK | PDZ domain-containing protein. (5891 aa) | ||||
PDPK1 | Protein kinase domain-containing protein. (347 aa) | ||||
RGN | Regucalcin. (299 aa) | ||||
G3SCJ7_GORGO | CNX domain-containing protein. (249 aa) | ||||
CD33 | CD33 molecule. (364 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
GCG | Glucagon. (180 aa) | ||||
AKAP5 | A-kinase anchoring protein 5. (427 aa) | ||||
G3SEV0_GORGO | Uncharacterized protein; Belongs to the calmodulin family. (152 aa) | ||||
NOS1 | Nitric oxide synthase 1. (1468 aa) | ||||
HCRT | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (524 aa) | ||||
STC1 | Stanniocalcin 1. (247 aa) | ||||
SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) | ||||
SARAF | Store-operated calcium entry associated regulatory factor. (340 aa) | ||||
G3SHM7_GORGO | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa) | ||||
LILRA5 | Leukocyte immunoglobulin like receptor A5. (300 aa) | ||||
G3SI79_GORGO | Uncharacterized protein. (229 aa) | ||||
CXCR3 | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
ENSGGOP00000028898 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa) | ||||
R3HDM2 | R3H domain containing 2. (1034 aa) | ||||
STAC2 | SH3 and cysteine rich domain 2. (404 aa) | ||||
MS4A1 | Membrane spanning 4-domains A1. (297 aa) | ||||
CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) | ||||
CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa) | ||||
ENSGGOP00000031130 | Uncharacterized protein. (189 aa) | ||||
ENSGGOP00000031235 | Uncharacterized protein; Belongs to the calmodulin family. (129 aa) | ||||
ENSGGOP00000031578 | Rad60-SLD domain-containing protein. (84 aa) | ||||
ENSGGOP00000031606 | Stromal interaction molecule 1. (791 aa) | ||||
ENSGGOP00000032040 | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) | ||||
ENSGGOP00000032522 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa) | ||||
ENSGGOP00000032712 | Uncharacterized protein. (264 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (644 aa) | ||||
ENSGGOP00000033982 | Uncharacterized protein. (256 aa) | ||||
CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) | ||||
PRNP | Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (253 aa) | ||||
ENSGGOP00000034427 | Calpain 3; Belongs to the peptidase C2 family. (821 aa) | ||||
EHD3 | EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (553 aa) | ||||
ENSGGOP00000036219 | annotation not available (193 aa) | ||||
CXCL11 | C-X-C motif chemokine. (94 aa) | ||||
ENSGGOP00000037329 | R3H domain containing 1. (1101 aa) | ||||
DMD | Dystrophin. (3685 aa) | ||||
ENSGGOP00000037657 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) | ||||
PDE4D | Phosphodiesterase. (748 aa) | ||||
UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) | ||||
NIPSNAP2 | Nipsnap homolog 2. (259 aa) | ||||
PPP3R1 | Uncharacterized protein. (189 aa) | ||||
ENSGGOP00000039905 | Uncharacterized protein. (142 aa) | ||||
HOMER2 | Homer scaffold protein 2. (356 aa) | ||||
P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa) | ||||
DRD1 | Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
ENSGGOP00000040681 | Uncharacterized protein; Belongs to the calmodulin family. (70 aa) | ||||
ENSGGOP00000040850 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa) | ||||
CACNB4 | Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa) | ||||
ENSGGOP00000041843 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa) | ||||
ENSGGOP00000042059 | Ubiquitin-like domain-containing protein. (146 aa) | ||||
TMBIM6 | Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (295 aa) | ||||
SMIM6 | Small integral membrane protein 6. (62 aa) | ||||
ENSGGOP00000043662 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa) | ||||
ENSGGOP00000043921 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa) | ||||
ENSGGOP00000044572 | Diaphanous related formin 1. (1242 aa) | ||||
CACNB1 | SH3 domain-containing protein. (119 aa) | ||||
ENSGGOP00000044877 | Uncharacterized protein; Belongs to the calmodulin family. (123 aa) | ||||
ENSGGOP00000045245 | Ryanodine receptor 2. (4768 aa) | ||||
ENSGGOP00000045869 | Rad60-SLD domain-containing protein. (95 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (300 aa) | ||||
CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa) | ||||
WNK3 | WNK lysine deficient protein kinase 3. (1800 aa) | ||||
ENSGGOP00000047330 | Uncharacterized protein. (261 aa) | ||||
EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) | ||||
STRIT1 | Small transmembrane regulator of ion transport 1. (35 aa) | ||||
MRLN | Myoregulin. (46 aa) | ||||
ENSGGOP00000048104 | annotation not available (264 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
ENSGGOP00000048996 | Ig-like domain-containing protein. (180 aa) | ||||
STIM2 | Stromal interaction molecule 2. (842 aa) | ||||
PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) | ||||
SLN | Sarcolipin. (31 aa) | ||||
CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa) | ||||
HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa) | ||||
HOMER1 | Homer scaffold protein 1. (366 aa) |