(38 nodes) Inner ear receptor cell stereocilium organization network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LHFPL5	LHFPL tetraspan subfamily member 5. (219 aa)
	TRIP11	Thyroid hormone receptor interactor 11. (1979 aa)
	REST	RE1 silencing transcription factor. (1081 aa)
	PLS1	Plastin 1. (629 aa)
	GRXCR1	Glutaredoxin and cysteine rich domain containing 1. (290 aa)
	MKS1	MKS transition zone complex subunit 1. (559 aa)
	G3QL78_GORGO	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (334 aa)
	USH1G	USH1 protein network component sans. (461 aa)
	LRRC1	Leucine rich repeat containing 1. (524 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
	G3QZB8_GORGO	Cadherin related 23. (3263 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (353 aa)
	G3R439_GORGO	Hes family bHLH transcription factor 5. (165 aa)
	IFT27	Intraflagellar transport 27. (189 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
	PJVK	Pejvakin. (352 aa)
	TRIOBP	TRIO and F-actin binding protein. (2184 aa)
	TPRN	Taperin. (617 aa)
	GRXCR2	Glutaredoxin and cysteine rich domain containing 2. (248 aa)
	IFT88	Intraflagellar transport 88. (782 aa)
	STRC-2	Uncharacterized protein. (675 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	PDZD7	PDZ domain containing 7. (1027 aa)
	WHRN	Whirlin. (907 aa)
	G3RXD4_GORGO	USH1 protein network component harmonin. (899 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1248 aa)
	SCRIB	Scribble planar cell polarity protein. (1658 aa)
	IFT20	Intraflagellar transport 20. (158 aa)
	PCDH15	Protocadherin related 15. (1960 aa)
	MYO7A	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2219 aa)
	CTHRC1	Collagen triple helix repeat containing 1. (243 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	ENSGGOP00000042549	Uncharacterized protein. (75 aa)
	ENSGGOP00000041284	Tetratricopeptide repeat domain 8. (531 aa)
	ENSGGOP00000032423	Clarin 1. (245 aa)
	ENSGGOP00000029961	CECR2 histone acetyl-lysine reader. (1420 aa)
	CLRN2	Clarin 2. (232 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRV1	ENSGGOP00000032423	ENSGGOP00000010724	ENSGGOP00000032423	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Clarin 1.	0.672
ADGRV1	G3QZB8_GORGO	ENSGGOP00000010724	ENSGGOP00000008224	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Cadherin related 23.	0.815
ADGRV1	G3RXD4_GORGO	ENSGGOP00000010724	ENSGGOP00000020470	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	USH1 protein network component harmonin.	0.799
ADGRV1	GRXCR1	ENSGGOP00000010724	ENSGGOP00000002834	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Glutaredoxin and cysteine rich domain containing 1.	0.481
ADGRV1	LHFPL5	ENSGGOP00000010724	ENSGGOP00000027269	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	LHFPL tetraspan subfamily member 5.	0.483
ADGRV1	MYO7A	ENSGGOP00000010724	ENSGGOP00000047463	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.793
ADGRV1	PCDH15	ENSGGOP00000010724	ENSGGOP00000048215	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Protocadherin related 15.	0.795
ADGRV1	PDZD7	ENSGGOP00000010724	ENSGGOP00000018367	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	PDZ domain containing 7.	0.817
ADGRV1	STRC-2	ENSGGOP00000010724	ENSGGOP00000017826	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.449
ADGRV1	USH1G	ENSGGOP00000010724	ENSGGOP00000003255	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	USH1 protein network component sans.	0.782
ADGRV1	WHRN	ENSGGOP00000010724	ENSGGOP00000019513	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	Whirlin.	0.959
CLRN2	GRXCR2	ENSGGOP00000024953	ENSGGOP00000013540	Clarin 2.	Glutaredoxin and cysteine rich domain containing 2.	0.454
ENSGGOP00000032423	ADGRV1	ENSGGOP00000032423	ENSGGOP00000010724	Clarin 1.	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	0.672
ENSGGOP00000032423	ENSGGOP00000041284	ENSGGOP00000032423	ENSGGOP00000041284	Clarin 1.	Tetratricopeptide repeat domain 8.	0.430
ENSGGOP00000032423	G3QZB8_GORGO	ENSGGOP00000032423	ENSGGOP00000008224	Clarin 1.	Cadherin related 23.	0.666
ENSGGOP00000032423	G3RXD4_GORGO	ENSGGOP00000032423	ENSGGOP00000020470	Clarin 1.	USH1 protein network component harmonin.	0.672
ENSGGOP00000032423	MYO7A	ENSGGOP00000032423	ENSGGOP00000047463	Clarin 1.	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.714
ENSGGOP00000032423	PCDH15	ENSGGOP00000032423	ENSGGOP00000048215	Clarin 1.	Protocadherin related 15.	0.672
ENSGGOP00000032423	PDZD7	ENSGGOP00000032423	ENSGGOP00000018367	Clarin 1.	PDZ domain containing 7.	0.544
ENSGGOP00000032423	USH1G	ENSGGOP00000032423	ENSGGOP00000003255	Clarin 1.	USH1 protein network component sans.	0.668