STRINGSTRING
SREBF2 SREBF2 TCF15 TCF15 G3RGU7_GORGO G3RGU7_GORGO BHLHE41 BHLHE41 BHLHE40 BHLHE40 NEUROG1 NEUROG1 NEUROD1 NEUROD1 MYC MYC SNAI1 SNAI1 G3RWH6_GORGO G3RWH6_GORGO MYOD1 MYOD1 CRY1 CRY1 CIART CIART NEUROD2 NEUROD2 ZEB1 ZEB1 HIF1A HIF1A TCF4 TCF4 ARNTL2 ARNTL2 MAX MAX PPARG PPARG TAL1 TAL1 ARNTL ARNTL MITF MITF NEUROG2 NEUROG2 TFAP4 TFAP4 SNAI2 SNAI2 MYOG MYOG TCF21 TCF21 ASCL1 ASCL1 CLOCK CLOCK PER1 PER1 HAND2 HAND2 GATA3 GATA3 G3QU62_GORGO G3QU62_GORGO ASCL2 ASCL2 TCF12 TCF12 HES1 HES1 NR1D1 NR1D1 PRMT5 PRMT5 HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SREBF2Sterol regulatory element binding transcription factor 2. (1146 aa)
TCF15Transcription factor 15. (198 aa)
G3RGU7_GORGOUncharacterized protein. (251 aa)
BHLHE41Basic helix-loop-helix family member e41. (419 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
NEUROG1Neurogenin 1. (237 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
G3RWH6_GORGOTranscription factor 3. (673 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
CRY1Cryptochrome circadian regulator 1. (623 aa)
CIARTCircadian associated repressor of transcription. (385 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1108 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
TCF4Transcription factor 4. (773 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (636 aa)
MAXMYC associated factor X. (148 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
NEUROG2Neurogenin 2. (272 aa)
TFAP4Transcription factor AP-4. (338 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
MYOGMyogenin. (249 aa)
TCF21Transcription factor 21. (179 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (234 aa)
CLOCKClock circadian regulator. (847 aa)
PER1Period circadian regulator 1. (1290 aa)
HAND2Heart and neural crest derivatives expressed 2. (198 aa)
GATA3GATA binding protein 3. (444 aa)
G3QU62_GORGOMYB binding protein 1a. (1114 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)
TCF12Transcription factor 12. (706 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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