(12 nodes) Podocyte development network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3QEY9_GORGO	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (560 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1265 aa)
	NOTCH2	Notch receptor 2. (2373 aa)
	MYO1E	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
	LAMB2	Laminin subunit beta 2. (1798 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NPHS2	NPHS2 stomatin family member, podocin. (383 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	ENSGGOP00000024523	annotation not available (408 aa)
	NPHS1	NPHS1 adhesion molecule, nephrin. (1280 aa)
	ASXL1	ASXL transcriptional regulator 1. (1537 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3QEY9_GORGO	NPHS1	ENSGGOP00000000846	ENSGGOP00000028097	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	NPHS1 adhesion molecule, nephrin.	0.683
G3QEY9_GORGO	NPHS2	ENSGGOP00000000846	ENSGGOP00000014978	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	NPHS2 stomatin family member, podocin.	0.674
IQGAP1	NPHS1	ENSGGOP00000049323	ENSGGOP00000028097	IQ motif containing GTPase activating protein 1.	NPHS1 adhesion molecule, nephrin.	0.816
IQGAP1	NPHS2	ENSGGOP00000049323	ENSGGOP00000014978	IQ motif containing GTPase activating protein 1.	NPHS2 stomatin family member, podocin.	0.469
JAG1	NOTCH2	ENSGGOP00000020660	ENSGGOP00000003937	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.976
MAGI2	NPHS1	ENSGGOP00000001284	ENSGGOP00000028097	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	NPHS1 adhesion molecule, nephrin.	0.525
MYO1E	NPHS2	ENSGGOP00000007489	ENSGGOP00000014978	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	NPHS2 stomatin family member, podocin.	0.434
NOTCH2	JAG1	ENSGGOP00000003937	ENSGGOP00000020660	Notch receptor 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.976
NPHS1	G3QEY9_GORGO	ENSGGOP00000028097	ENSGGOP00000000846	NPHS1 adhesion molecule, nephrin.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.683
NPHS1	IQGAP1	ENSGGOP00000028097	ENSGGOP00000049323	NPHS1 adhesion molecule, nephrin.	IQ motif containing GTPase activating protein 1.	0.816
NPHS1	MAGI2	ENSGGOP00000028097	ENSGGOP00000001284	NPHS1 adhesion molecule, nephrin.	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	0.525
NPHS1	NPHS2	ENSGGOP00000028097	ENSGGOP00000014978	NPHS1 adhesion molecule, nephrin.	NPHS2 stomatin family member, podocin.	0.972
NPHS2	G3QEY9_GORGO	ENSGGOP00000014978	ENSGGOP00000000846	NPHS2 stomatin family member, podocin.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.674
NPHS2	IQGAP1	ENSGGOP00000014978	ENSGGOP00000049323	NPHS2 stomatin family member, podocin.	IQ motif containing GTPase activating protein 1.	0.469
NPHS2	MYO1E	ENSGGOP00000014978	ENSGGOP00000007489	NPHS2 stomatin family member, podocin.	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.434
NPHS2	NPHS1	ENSGGOP00000014978	ENSGGOP00000028097	NPHS2 stomatin family member, podocin.	NPHS1 adhesion molecule, nephrin.	0.972