STRINGSTRING
G3S986_GORGO G3S986_GORGO ENSGGOP00000051962 ENSGGOP00000051962 ATP2B4-2 ATP2B4-2 ENSGGOP00000051472 ENSGGOP00000051472 HOMER1 HOMER1 PHF6 PHF6 ENSGGOP00000049784 ENSGGOP00000049784 CD163 CD163 ENSGGOP00000049122 ENSGGOP00000049122 ENSGGOP00000048403 ENSGGOP00000048403 TREM1 TREM1 DSP DSP ENSGGOP00000042381 ENSGGOP00000042381 TCOF1 TCOF1 SYK SYK ATP2B4 ATP2B4 KCNA5 KCNA5 KRT15 KRT15 KRT18 KRT18 CIT CIT YWHAE YWHAE ITPR2 ITPR2 PDE4D PDE4D ENSGGOP00000037735 ENSGGOP00000037735 ENSGGOP00000037731 ENSGGOP00000037731 ENSGGOP00000036218 ENSGGOP00000036218 P2RY1 P2RY1 G3QDP7_GORGO G3QDP7_GORGO ATG4B ATG4B PSAPL1 PSAPL1 KRT5 KRT5 CACNA1G CACNA1G MAP2K1 MAP2K1 IL6ST IL6ST NLGN1 NLGN1 DLL1 DLL1 PANX-2 PANX-2 DLG4 DLG4 CRK CRK IKBKB IKBKB FYN FYN G3R0F2_GORGO G3R0F2_GORGO CHUK CHUK VIM VIM GRM2 GRM2 G3R8T5_GORGO G3R8T5_GORGO LYN LYN SCN5A SCN5A NLGN3 NLGN3 KCNQ1 KCNQ1 G3RD86_GORGO G3RD86_GORGO G3RFD8_GORGO G3RFD8_GORGO ENSGGOP00000035103 ENSGGOP00000035103 ENSGGOP00000033404 ENSGGOP00000033404 ENSGGOP00000032522 ENSGGOP00000032522 ENSGGOP00000032413 ENSGGOP00000032413 BAIAP2 BAIAP2 ENSGGOP00000030121 ENSGGOP00000030121 ENSGGOP00000030108 ENSGGOP00000030108 ENSGGOP00000029762 ENSGGOP00000029762 NCK2 NCK2 ENSGGOP00000028898 ENSGGOP00000028898 G3SIR7_GORGO G3SIR7_GORGO PLCG2 PLCG2 G3SHM7_GORGO G3SHM7_GORGO NLGN4X NLGN4X NOS1 NOS1 AKAP5 AKAP5 G3SE94_GORGO G3SE94_GORGO G3SE25_GORGO G3SE25_GORGO BRAF BRAF G3S9X8_GORGO G3S9X8_GORGO G3S4R8_GORGO G3S4R8_GORGO CDC37 CDC37 ADCY5 ADCY5 PSAP PSAP CACNA1H CACNA1H MAP3K7 MAP3K7 LRP4 LRP4 SRC SRC NOS3 NOS3 G3RKX6_GORGO G3RKX6_GORGO XRCC6 XRCC6 GRM3 GRM3 TREM2 TREM2 CAV2 CAV2 CRIPT CRIPT KRT8 KRT8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3S986_GORGOIF rod domain-containing protein; Belongs to the intermediate filament family. (469 aa)
ENSGGOP00000051962SAP domain-containing protein. (226 aa)
ATP2B4-2Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (554 aa)
ENSGGOP00000051472IF rod domain-containing protein; Belongs to the intermediate filament family. (419 aa)
HOMER1Homer scaffold protein 1. (366 aa)
PHF6PHD finger protein 6. (365 aa)
ENSGGOP00000049784IF rod domain-containing protein; Belongs to the intermediate filament family. (299 aa)
CD163CD163 molecule. (1156 aa)
ENSGGOP00000049122Uncharacterized protein. (305 aa)
ENSGGOP00000048403Lep_receptor_Ig domain-containing protein. (92 aa)
TREM1IG domain-containing protein. (249 aa)
DSPDesmoplakin. (2868 aa)
ENSGGOP00000042381Uncharacterized protein. (1742 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1448 aa)
SYKTyrosine-protein kinase. (635 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1225 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (456 aa)
KRT18Keratin 18; Belongs to the intermediate filament family. (430 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2075 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa)
PDE4DPhosphodiesterase. (748 aa)
ENSGGOP00000037735Uncharacterized protein. (471 aa)
ENSGGOP00000037731IF rod domain-containing protein; Belongs to the intermediate filament family. (458 aa)
ENSGGOP00000036218IF rod domain-containing protein; Belongs to the intermediate filament family. (443 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
G3QDP7_GORGOGlutamate ionotropic receptor delta type subunit 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (941 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (389 aa)
PSAPL1Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. (521 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (590 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IL6STFibronectin type-III domain-containing protein. (329 aa)
NLGN1Neuroligin 1. (823 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
PANX-2Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (745 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
FYNTyrosine-protein kinase. (537 aa)
G3R0F2_GORGOMitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CHUKIKKbetaNEMObind domain-containing protein. (434 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
G3R8T5_GORGOParkinsonism associated deglycase. (155 aa)
LYNTyrosine-protein kinase. (512 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
NLGN3Neuroligin 3. (848 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
G3RFD8_GORGOIF rod domain-containing protein; Belongs to the intermediate filament family. (477 aa)
ENSGGOP00000035103Protein kinase domain-containing protein. (379 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
ENSGGOP0000003252214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa)
ENSGGOP00000032413IF rod domain-containing protein; Belongs to the intermediate filament family. (377 aa)
BAIAP2BAI1 associated protein 2. (548 aa)
ENSGGOP00000030121Uncharacterized protein. (354 aa)
ENSGGOP00000030108Ku domain-containing protein. (592 aa)
ENSGGOP00000029762DJ-1_PfpI domain-containing protein. (168 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSGGOP0000002889814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa)
G3SIR7_GORGOKu domain-containing protein. (334 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
G3SHM7_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa)
NLGN4XNeuroligin 4 X-linked. (873 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
G3SE94_GORGOIF rod domain-containing protein; Belongs to the intermediate filament family. (360 aa)
G3SE25_GORGOSH3 and multiple ankyrin repeat domains 3. (1605 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
G3S9X8_GORGOIF rod domain-containing protein; Belongs to the intermediate filament family. (413 aa)
G3S4R8_GORGOIF rod domain-containing protein; Belongs to the intermediate filament family. (582 aa)
CDC37Cell division cycle 37. (378 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1257 aa)
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2349 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
LRP4LDL receptor related protein 4. (1947 aa)
SRCTyrosine-protein kinase. (542 aa)
NOS3Nitric oxide synthase 3. (997 aa)
G3RKX6_GORGOPotassium voltage-gated channel subfamily H member 2. (955 aa)
XRCC6X-ray repair cross complementing 6. (609 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
KRT8Keratin 8; Belongs to the intermediate filament family. (511 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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