(12 nodes) Transcription preinitiation complex network (Gorilla gorilla)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	ENSGGOP00000037296	TFIIF_beta domain-containing protein. (102 aa)
	GTF2A1	General transcription factor IIA subunit 1. (370 aa)
	GTF2F2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	BRF1	BRF1 RNA polymerase III transcription initiation factor subunit. (677 aa)
	GTF2H3	General transcription factor IIH subunit 3. (308 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	TBP	TATA-box binding protein. (332 aa)
	BRF2	BRF2 RNA polymerase III transcription initiation factor subunit. (419 aa)
	ERCC3	ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
	GTF2B	General transcription factor IIB. (316 aa)
	GTF2E1	General transcription factor IIE subunit 1. (439 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRF1	BRF2	ENSGGOP00000007455	ENSGGOP00000012574	BRF1 RNA polymerase III transcription initiation factor subunit.	BRF2 RNA polymerase III transcription initiation factor subunit.	0.668
BRF1	ERCC3	ENSGGOP00000007455	ENSGGOP00000014886	BRF1 RNA polymerase III transcription initiation factor subunit.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.545
BRF1	GTF2B	ENSGGOP00000007455	ENSGGOP00000020269	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIB.	0.705
BRF1	GTF2E1	ENSGGOP00000007455	ENSGGOP00000021689	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIE subunit 1.	0.585
BRF1	GTF2F2	ENSGGOP00000007455	ENSGGOP00000006517	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.418
BRF1	GTF2H3	ENSGGOP00000007455	ENSGGOP00000008967	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIH subunit 3.	0.454
BRF1	TAF10	ENSGGOP00000007455	ENSGGOP00000039527	BRF1 RNA polymerase III transcription initiation factor subunit.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.403
BRF1	TBP	ENSGGOP00000007455	ENSGGOP00000011550	BRF1 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein.	0.991
BRF2	BRF1	ENSGGOP00000012574	ENSGGOP00000007455	BRF2 RNA polymerase III transcription initiation factor subunit.	BRF1 RNA polymerase III transcription initiation factor subunit.	0.668
BRF2	ERCC3	ENSGGOP00000012574	ENSGGOP00000014886	BRF2 RNA polymerase III transcription initiation factor subunit.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.540
BRF2	GTF2B	ENSGGOP00000012574	ENSGGOP00000020269	BRF2 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIB.	0.685
BRF2	GTF2E1	ENSGGOP00000012574	ENSGGOP00000021689	BRF2 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIE subunit 1.	0.551
BRF2	GTF2F2	ENSGGOP00000012574	ENSGGOP00000006517	BRF2 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.420
BRF2	GTF2H3	ENSGGOP00000012574	ENSGGOP00000008967	BRF2 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIH subunit 3.	0.441
BRF2	TBP	ENSGGOP00000012574	ENSGGOP00000011550	BRF2 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein.	0.995
ENSGGOP00000037296	ERCC3	ENSGGOP00000037296	ENSGGOP00000014886	TFIIF_beta domain-containing protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.901
ENSGGOP00000037296	ESR1	ENSGGOP00000037296	ENSGGOP00000009454	TFIIF_beta domain-containing protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.415
ENSGGOP00000037296	GTF2A1	ENSGGOP00000037296	ENSGGOP00000003212	TFIIF_beta domain-containing protein.	General transcription factor IIA subunit 1.	0.910
ENSGGOP00000037296	GTF2B	ENSGGOP00000037296	ENSGGOP00000020269	TFIIF_beta domain-containing protein.	General transcription factor IIB.	0.976
ENSGGOP00000037296	GTF2E1	ENSGGOP00000037296	ENSGGOP00000021689	TFIIF_beta domain-containing protein.	General transcription factor IIE subunit 1.	0.967