(14 nodes) STAT family protein binding network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3RCP0_GORGO	HSF_DOMAIN domain-containing protein. (527 aa)
	FAM162A	Family with sequence similarity 162 member A. (172 aa)
	CEBPA	BZIP domain-containing protein. (141 aa)
	ENSGGOP00000034298	Histone H2B; Belongs to the histone H2B family. (126 aa)
	PTPRT	Protein tyrosine phosphatase receptor type T. (1451 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (387 aa)
	G3RMK1_GORGO	FAM220 domain-containing protein. (277 aa)
	G3RMA5_GORGO	Tyrosine-protein phosphatase non-receptor type. (415 aa)
	DTX3L	Deltex E3 ubiquitin ligase 3L. (740 aa)
	PARP9	Poly(ADP-ribose) polymerase family member 9. (819 aa)
	EP300	E1A binding protein p300. (2416 aa)
	SPI1	Spi-1 proto-oncogene. (271 aa)
	FAM220A	FAM220 domain-containing protein. (259 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPA	EP300	ENSGGOP00000038288	ENSGGOP00000008032	BZIP domain-containing protein.	E1A binding protein p300.	0.722
CEBPA	PPARG	ENSGGOP00000038288	ENSGGOP00000032598	BZIP domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.912
CEBPA	SPI1	ENSGGOP00000038288	ENSGGOP00000006346	BZIP domain-containing protein.	Spi-1 proto-oncogene.	0.869
DTX3L	PARP9	ENSGGOP00000015585	ENSGGOP00000015575	Deltex E3 ubiquitin ligase 3L.	Poly(ADP-ribose) polymerase family member 9.	0.756
ENSGGOP00000034298	EP300	ENSGGOP00000034298	ENSGGOP00000008032	Histone H2B; Belongs to the histone H2B family.	E1A binding protein p300.	0.408
EP300	CEBPA	ENSGGOP00000008032	ENSGGOP00000038288	E1A binding protein p300.	BZIP domain-containing protein.	0.722
EP300	ENSGGOP00000034298	ENSGGOP00000008032	ENSGGOP00000034298	E1A binding protein p300.	Histone H2B; Belongs to the histone H2B family.	0.408
EP300	G3RCP0_GORGO	ENSGGOP00000008032	ENSGGOP00000013273	E1A binding protein p300.	HSF_DOMAIN domain-containing protein.	0.447
EP300	PPARG	ENSGGOP00000008032	ENSGGOP00000032598	E1A binding protein p300.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.975
EP300	SPI1	ENSGGOP00000008032	ENSGGOP00000006346	E1A binding protein p300.	Spi-1 proto-oncogene.	0.933
G3RCP0_GORGO	EP300	ENSGGOP00000013273	ENSGGOP00000008032	HSF_DOMAIN domain-containing protein.	E1A binding protein p300.	0.447
PARP9	DTX3L	ENSGGOP00000015575	ENSGGOP00000015585	Poly(ADP-ribose) polymerase family member 9.	Deltex E3 ubiquitin ligase 3L.	0.756
PPARG	CEBPA	ENSGGOP00000032598	ENSGGOP00000038288	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	BZIP domain-containing protein.	0.912
PPARG	EP300	ENSGGOP00000032598	ENSGGOP00000008032	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	E1A binding protein p300.	0.975
PPARG	SPI1	ENSGGOP00000032598	ENSGGOP00000006346	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Spi-1 proto-oncogene.	0.467
SPI1	CEBPA	ENSGGOP00000006346	ENSGGOP00000038288	Spi-1 proto-oncogene.	BZIP domain-containing protein.	0.869
SPI1	EP300	ENSGGOP00000006346	ENSGGOP00000008032	Spi-1 proto-oncogene.	E1A binding protein p300.	0.933
SPI1	PPARG	ENSGGOP00000006346	ENSGGOP00000032598	Spi-1 proto-oncogene.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.467