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| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | G0S2 | G0/G1 switch protein 2; Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. (103 aa) |
| | BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (462 aa) |
| | GPR3 | G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (488 aa) |
| | ENSGGOP00000043046 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (345 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1032 aa) |
| | TRPM8 | Transient receptor potential cation channel subfamily M member 8. (1104 aa) |
| | THRA | Uncharacterized protein. (595 aa) |
| | IRF4 | Interferon regulatory factor 4. (451 aa) |
| | PCTP | Phosphatidylcholine transfer protein. (219 aa) |
| | ENSGGOP00000048202 | Uncharacterized protein. (210 aa) |
| | ESRRG | Estrogen related receptor gamma. (470 aa) |
| | SLN | Sarcolipin. (31 aa) |
| | ENSGGOP00000050742 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (108 aa) |
| | ENSGGOP00000052414 | Uncharacterized protein. (81 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (129 aa) |
| | LEPR | Leptin receptor. (1154 aa) |
| | DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4646 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | G3QDF2_GORGO | Transient receptor potential cation channel subfamily V member 2. (630 aa) |
| | NOVA2 | NOVA alternative splicing regulator 2. (466 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | HOXC10 | Homeobox C10. (342 aa) |
| | OMA1 | OMA1 zinc metallopeptidase. (524 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | ACHE | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa) |
| | FLCN | Folliculin. (579 aa) |
| | EBF2 | EBF transcription factor 2. (575 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1027 aa) |
| | DECR1 | 2,4-dienoyl-CoA reductase 1. (335 aa) |
| | GNAS | GNAS complex locus. (985 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | PRDM16 | PR/SET domain 16. (1263 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | ZNF516 | Zinc finger protein 516. (1148 aa) |
| | CPT2 | Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (670 aa) |
| | ARRDC3 | Arrestin domain containing 3. (414 aa) |
| | PER2 | Period circadian regulator 2. (1255 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1291 aa) |
| | NRDC | Nardilysin convertase. (1219 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | ADIPOR1 | Adiponectin receptor 1. (375 aa) |
| | G3QR91_GORGO | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | ADRB2 | Adrenoceptor beta 2. (413 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (461 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | PHOX2B | Paired like homeobox 2B. (314 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (594 aa) |
| | ACADL | Acyl-CoA dehydrogenase long chain. (430 aa) |
| | PEMT | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (236 aa) |
| | KDM3A | Lysine demethylase 3A. (1321 aa) |
| | ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa) |
| | FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | PLAC8 | Placenta associated 8. (115 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (997 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | ACOT11 | Uncharacterized protein. (501 aa) |
| | NOTCH1 | Uncharacterized protein. (1606 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | FH | Fumarate hydratase. (510 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | CMKLR1 | Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | G3R4Q6_GORGO | Uncharacterized protein. (431 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa) |
| | ALPL | Alkaline phosphatase. (524 aa) |
| | SLC25A44 | Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | G3R859_GORGO | Uncharacterized protein. (100 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (541 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) |
| | ALMS1 | ALMS1 centrosome and basal body associated protein. (4120 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) |
| | G3RCP0_GORGO | HSF_DOMAIN domain-containing protein. (527 aa) |
| | ADIPOR2 | Adiponectin receptor 2. (386 aa) |
| | ACOT13 | Acyl-CoA thioesterase 13. (140 aa) |
| | NPR3 | Natriuretic peptide receptor 3. (541 aa) |
| | G3RF44_GORGO | Forkhead box C2. (442 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1823 aa) |
| | KDM6B | Lysine demethylase 6B. (1687 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | DBH | Dopamine beta-hydroxylase. (617 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (155 aa) |
| | MFAP2 | Microfibril associated protein 2. (183 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | G3RJZ9_GORGO | RB transcriptional corepressor 1. (756 aa) |
| | ZNF423 | Zinc finger protein 423. (1284 aa) |
| | PTH2R | Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa) |
| | CCR2 | C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) |
| | NOVA1 | NOVA alternative splicing regulator 1. (507 aa) |
| | APC | APC regulator of WNT signaling pathway. (2844 aa) |
| | PGAM5 | PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa) |
| | GATM | Glycine amidinotransferase. (423 aa) |
| | DIO2 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (145 aa) |
| | CIDEA | Cell death inducing DFFA like effector a. (253 aa) |
| | G3S0U2_GORGO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (90 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa) |
| | OXTR | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (929 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (782 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | ADRB1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (291 aa) |
| | LCN2 | Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (213 aa) |
| | HCRT | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa) |
| | PWWP2B | PWWP domain containing 2B. (572 aa) |
| | G3SJA5_GORGO | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa) |
| | DOCK7 | Dedicator of cytokinesis 7; Belongs to the DOCK family. (2137 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | ENSGGOP00000030478 | Tyrosine-protein kinase. (1151 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (944 aa) |
| | ENSGGOP00000032065 | Uncharacterized protein. (245 aa) |
| | ENSGGOP00000032087 | BZIP domain-containing protein. (342 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1095 aa) |
| | ENSGGOP00000033459 | BZIP domain-containing protein. (350 aa) |
| | ENSGGOP00000033713 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (125 aa) |
| | ENSGGOP00000033934 | Uncharacterized protein. (318 aa) |
| | EPAS1 | Uncharacterized protein. (574 aa) |
| | ENSGGOP00000034697 | Hydroxyacyl-CoA dehydrogenase. (390 aa) |
| | FFAR4 | Free fatty acid receptor 4. (377 aa) |
| | YBX2 | Y-box binding protein 2. (374 aa) |
| | LPIN1 | Lipin 1. (975 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa) |
| | ENSGGOP00000036703 | CCR4-NOT transcription complex subunit 3. (781 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (628 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) |
| | DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa) |
