STRINGSTRING
OPTN OPTN ENSGGOP00000050852 ENSGGOP00000050852 TBK1 TBK1 NOD1 NOD1 MAPK3 MAPK3 RNF31 RNF31 RIPK2 RIPK2 NOD2 NOD2 LRSAM1 LRSAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OPTNOptineurin. (577 aa)
ENSGGOP00000050852annotation not available (362 aa)
TBK1TANK binding kinase 1. (729 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
RNF31Uncharacterized protein. (1072 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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