STRINGSTRING
PSMD5 PSMD5 G3QCU3_GORGO G3QCU3_GORGO FCN3 FCN3 PSMC4 PSMC4 PSMD11 PSMD11 MASP1 MASP1 PSMA1 PSMA1 CASP9 CASP9 RAD23B RAD23B HSPB1 HSPB1 PSMD10 PSMD10 VCP VCP CASP2 CASP2 F8 F8 UCHL5 UCHL5 PSMD8 PSMD8 UBE3C UBE3C PSMA7 PSMA7 HTRA2 HTRA2 PIGU PIGU PSMA2 PSMA2 G3QUL5_GORGO G3QUL5_GORGO PSMC5 PSMC5 PSMD9 PSMD9 F2 F2 COLEC10 COLEC10 PSMB3 PSMB3 PSMB11 PSMB11 G3QYC6_GORGO G3QYC6_GORGO ADRM1 ADRM1 PSMC2 PSMC2 PLAUR PLAUR PIGK PIGK F12 F12 PIGS PIGS G3R2Q5_GORGO G3R2Q5_GORGO PSMD7 PSMD7 F11 F11 PSMB4 PSMB4 PSMC1 PSMC1 F5 F5 KIAA2012 KIAA2012 PSMB8 PSMB8 PSMB9 PSMB9 PSMB7 PSMB7 ECPAS ECPAS PSMA6 PSMA6 PSMB10 PSMB10 G3RDV9_GORGO G3RDV9_GORGO F10 F10 PSMD12 PSMD12 PLAU PLAU PSMD14 PSMD14 UBQLN1 UBQLN1 PSMA8 PSMA8 PSMC3 PSMC3 G3RPJ8_GORGO G3RPJ8_GORGO CFH CFH MASP2 MASP2 PSMB1 PSMB1 PSMD1 PSMD1 KLKB1 KLKB1 G3S091_GORGO G3S091_GORGO CRADD CRADD TXNL1 TXNL1 PSMD2 PSMD2 PSME2 PSME2 C3 C3 CAPNS1 CAPNS1 G3SB50_GORGO G3SB50_GORGO PSMD3 PSMD3 FCN2 FCN2 PSMB2 PSMB2 CASP6 CASP6 PIDD1 PIDD1 PSMD13 PSMD13 ZFAND2B ZFAND2B ENSGGOP00000030743 ENSGGOP00000030743 ENSGGOP00000031133 ENSGGOP00000031133 ENSGGOP00000031459 ENSGGOP00000031459 ENSGGOP00000031928 ENSGGOP00000031928 ENSGGOP00000032441 ENSGGOP00000032441 ENSGGOP00000032610 ENSGGOP00000032610 ENSGGOP00000032659 ENSGGOP00000032659 ENSGGOP00000033404 ENSGGOP00000033404 ENSGGOP00000033543 ENSGGOP00000033543 PIGT PIGT ENSGGOP00000034948 ENSGGOP00000034948 ENSGGOP00000035581 ENSGGOP00000035581 PSMA4 PSMA4 ENSGGOP00000036577 ENSGGOP00000036577 PSMF1 PSMF1 PSMC6 PSMC6 COLEC11 COLEC11 PSMA3 PSMA3 ENSGGOP00000038972 ENSGGOP00000038972 PSMD4 PSMD4 UBE3A UBE3A F3 F3 MBL2 MBL2 PSME4 PSME4 ENSGGOP00000039716 ENSGGOP00000039716 ENSGGOP00000041538 ENSGGOP00000041538 PSMB5 PSMB5 ENSGGOP00000042177 ENSGGOP00000042177 PSME3 PSME3 GPAA1 GPAA1 SEM1 SEM1 PSME1 PSME1 ENSGGOP00000043985 ENSGGOP00000043985 CASP7 CASP7 ENSGGOP00000045267 ENSGGOP00000045267 ZFAND2A ZFAND2A ENSGGOP00000045976 ENSGGOP00000045976 ENSGGOP00000046758 ENSGGOP00000046758 ENSGGOP00000048677 ENSGGOP00000048677 ENSGGOP00000048733 ENSGGOP00000048733 ENSGGOP00000048925 ENSGGOP00000048925 PSMB6 PSMB6 ENSGGOP00000049405 ENSGGOP00000049405 ENSGGOP00000050749 ENSGGOP00000050749 ENSGGOP00000051193 ENSGGOP00000051193 ENSGGOP00000051252 ENSGGOP00000051252
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
G3QCU3_GORGOSEM1 26S proteasome complex subunit. (111 aa)
FCN3Ficolin 3. (299 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (368 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
UBE3CUbiquitin protein ligase E3C. (1083 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U. (435 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
G3QUL5_GORGOProteasome endopeptidase complex. (183 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD9PDZ domain-containing protein. (223 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
COLEC10Collectin subfamily member 10. (277 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMB11Proteasome subunit beta. (300 aa)
G3QYC6_GORGOCalpain 2; Belongs to the peptidase C2 family. (673 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PLAURUncharacterized protein. (261 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (395 aa)
F12Coagulation factor XII. (671 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (555 aa)
G3R2Q5_GORGOE3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (932 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2170 aa)
KIAA2012KIAA2012. (1156 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (218 aa)
PSMB7Proteasome subunit beta. (277 aa)
ECPASEcm29 proteasome adaptor and scaffold. (2017 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB10Proteasome subunit beta. (273 aa)
G3RDV9_GORGOProteasomal ATPase associated factor 1. (333 aa)
F10Coagulation factor X. (488 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (436 aa)
PLAUPlasminogen activator, urokinase. (431 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
UBQLN1Ubiquilin 1. (589 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
G3RPJ8_GORGOProteasome 26S subunit, non-ATPase 6. (442 aa)
CFHComplement factor H. (1227 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
PSMB1Uncharacterized protein. (173 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
G3S091_GORGOProteasome endopeptidase complex. (237 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
TXNL1Thioredoxin like 1. (289 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSME2Proteasome activator subunit 2. (239 aa)
C3Complement C3. (1663 aa)
CAPNS1Calpain small subunit 1. (320 aa)
G3SB50_GORGOProtein C, inactivator of coagulation factors Va and VIIIa. (495 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
FCN2Ficolin 2. (313 aa)
PSMB2Proteasome subunit beta. (201 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
PIDD1P53-induced death domain protein 1. (910 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
ZFAND2BUncharacterized protein. (243 aa)
ENSGGOP00000030743AAA domain-containing protein; Belongs to the AAA ATPase family. (206 aa)
ENSGGOP00000031133Uncharacterized protein. (373 aa)
ENSGGOP00000031459AAA domain-containing protein. (407 aa)
ENSGGOP00000031928VWFA domain-containing protein. (352 aa)
ENSGGOP00000032441Uncharacterized protein. (226 aa)
ENSGGOP00000032610Uncharacterized protein. (142 aa)
ENSGGOP00000032659Proteasome endopeptidase complex. (246 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
ENSGGOP0000003354326S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (821 aa)
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (585 aa)
ENSGGOP00000034948MPN domain-containing protein. (290 aa)
ENSGGOP00000035581CSN8_PSD8_EIF3K domain-containing protein. (246 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSGGOP00000036577AAA domain-containing protein. (340 aa)
PSMF1Uncharacterized protein. (335 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (411 aa)
COLEC11Collectin subfamily member 11. (285 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSGGOP00000038972AAA domain-containing protein. (392 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (391 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa)
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (248 aa)
PSME4Proteasome activator subunit 4. (1832 aa)
ENSGGOP00000039716AAA domain-containing protein. (354 aa)
ENSGGOP00000041538ANK_REP_REGION domain-containing protein. (152 aa)
PSMB5Proteasome subunit beta. (271 aa)
ENSGGOP00000042177ANK_REP_REGION domain-containing protein. (199 aa)
PSME3Proteasome activator subunit 3. (265 aa)
GPAA1Glycosylphosphatidylinositol anchor attachment 1. (621 aa)
SEM1Uncharacterized protein. (119 aa)
PSME1Uncharacterized protein. (216 aa)
ENSGGOP00000043985Uncharacterized protein. (195 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (388 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
ZFAND2AZinc finger AN1-type containing 2A. (178 aa)
ENSGGOP00000045976Uncharacterized protein. (180 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
ENSGGOP00000048677Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (460 aa)
ENSGGOP00000048733RAD23 homolog A, nucleotide excision repair protein. (376 aa)
ENSGGOP00000048925Uncharacterized protein. (124 aa)
PSMB6Proteasome subunit beta. (244 aa)
ENSGGOP00000049405Uncharacterized protein. (233 aa)
ENSGGOP00000050749AAA domain-containing protein. (395 aa)
ENSGGOP00000051193Uncharacterized protein. (73 aa)
ENSGGOP00000051252Proteasome endopeptidase complex. (245 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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