STRINGSTRING
SIM1 SIM1 CENPVL3 CENPVL3 CCDC36 CCDC36 ENSGGOP00000043851 ENSGGOP00000043851 ENSGGOP00000044043 ENSGGOP00000044043 SMC1B SMC1B XPO1 XPO1 CENPO CENPO NDE1 NDE1 DSN1 DSN1 ENSGGOP00000044777 ENSGGOP00000044777 DCTN2 DCTN2 NCAPH NCAPH SMC2 SMC2 MEI4 MEI4 TEX11 TEX11 HORMAD1 HORMAD1 BUB1 BUB1 ENSGGOP00000047617 ENSGGOP00000047617 SYCP3 SYCP3 HORMAD2 HORMAD2 CHAMP1 CHAMP1 ENSGGOP00000050061 ENSGGOP00000050061 ENSGGOP00000050156 ENSGGOP00000050156 ENSGGOP00000050356 ENSGGOP00000050356 CENPE CENPE LRPPRC LRPPRC ENSGGOP00000051819 ENSGGOP00000051819 MEIKIN MEIKIN G3RRD3_GORGO G3RRD3_GORGO SPAG5 SPAG5 G3RT90_GORGO G3RT90_GORGO RNF212 RNF212 RRS1 RRS1 CENPQ CENPQ CNTD1 CNTD1 BOD1L1 BOD1L1 RGS12 RGS12 KNL1 KNL1 GLYATL3 GLYATL3 PRDM9 PRDM9 CENPVL2 CENPVL2 CENPVL1 CENPVL1 WAPL WAPL KAT5 KAT5 FAM43B FAM43B G3S5H5_GORGO G3S5H5_GORGO NDEL1 NDEL1 SUV39H1 SUV39H1 BANF1 BANF1 BOD1L2 BOD1L2 SYCE2 SYCE2 MAGEB6 MAGEB6 ZIM3 ZIM3 FAM43A FAM43A STAG3 STAG3 ZNF287 ZNF287 CENPA CENPA CENPU CENPU CDT1 CDT1 PHF2 PHF2 KIF2C KIF2C L3MBTL1 L3MBTL1 ESRRB ESRRB NCAPG2 NCAPG2 ENSGGOP00000029373 ENSGGOP00000029373 SIM2 SIM2 TTN TTN MEAF6 MEAF6 ENSGGOP00000031048 ENSGGOP00000031048 MDP1 MDP1 ENSGGOP00000031463 ENSGGOP00000031463 FKBP6 FKBP6 ENSGGOP00000032803 ENSGGOP00000032803 NCAPG NCAPG SLC39A1 SLC39A1 ENSGGOP00000034934 ENSGGOP00000034934 ENSGGOP00000035259 ENSGGOP00000035259 ENSGGOP00000035777 ENSGGOP00000035777 ENSGGOP00000035879 ENSGGOP00000035879 SPDL1 SPDL1 SLF1 SLF1 STAG1 STAG1 SGO2 SGO2 ENSGGOP00000038116 ENSGGOP00000038116 RAD9B RAD9B SYCP2 SYCP2 DCTN1 DCTN1 DYNLL1 DYNLL1 ENSGGOP00000040771 ENSGGOP00000040771 ENSGGOP00000040881 ENSGGOP00000040881 KIF22 KIF22 SKA3 SKA3 G3RF65_GORGO G3RF65_GORGO G3RHR8_GORGO G3RHR8_GORGO HMGB2 HMGB2 DYNC1LI1 DYNC1LI1 REC8 REC8 CCDC155 CCDC155 MLH1 MLH1 SMC5 SMC5 SKA1 SKA1 CHEK1 CHEK1 G3RP17_GORGO G3RP17_GORGO FBXO28 FBXO28 RAD21L1 RAD21L1 NIFK NIFK CENPT CENPT CTCF CTCF SHOC1 SHOC1 KNSTRN KNSTRN REC114 REC114 DYNC1I1 DYNC1I1 G3RCP0_GORGO G3RCP0_GORGO SYCP2L SYCP2L RSKR RSKR G3RA54_GORGO G3RA54_GORGO MAGEB2 MAGEB2 RAD21 RAD21 NRG3 NRG3 G3R6L0_GORGO G3R6L0_GORGO DMC1 DMC1 G3R6C8_GORGO G3R6C8_GORGO G3R5X1_GORGO G3R5X1_GORGO G3R5V1_GORGO G3R5V1_GORGO BOD1 BOD1 G3R5R0_GORGO G3R5R0_GORGO G3R534_GORGO G3R534_GORGO C14H14orf39 C14H14orf39 MIS12 MIS12 BRD4 BRD4 P3H4 P3H4 G3R3B3_GORGO G3R3B3_GORGO MTBP MTBP CENPC CENPC NCAPD2 NCAPD2 SPO11 SPO11 TTK TTK PINX1 PINX1 NSMCE2 NSMCE2 BLM BLM G3QX71_GORGO G3QX71_GORGO HUS1B HUS1B PDS5A PDS5A ZWINT ZWINT G3QW19_GORGO G3QW19_GORGO F2 F2 KIF2B KIF2B G3QV95_GORGO G3QV95_GORGO NCAPD3 NCAPD3 MIS18BP1 MIS18BP1 C1H1orf146 C1H1orf146 NSMCE1 NSMCE1 SGO1 SGO1 SS18L1 SS18L1 TRAPPC12 TRAPPC12 NEK2 NEK2 G3QRL9_GORGO G3QRL9_GORGO CENPK CENPK RAD1 RAD1 MKI67 MKI67 STAG2 STAG2 SMC6 SMC6 TPR TPR NSL1 NSL1 SYCE1 SYCE1 G3QK51_GORGO G3QK51_GORGO SYCE3 SYCE3 HJURP HJURP CHMP7 CHMP7 MAD2L1 MAD2L1 CENPF CENPF BUB1B BUB1B G3QIE9_GORGO G3QIE9_GORGO G3QI01_GORGO G3QI01_GORGO ESPL1 ESPL1 CENPH CENPH SMC4 SMC4 G3RED9_GORGO G3RED9_GORGO RASSF2 RASSF2 CKAP5 CKAP5 FBXO28-2 FBXO28-2 ENSGGOP00000042938 ENSGGOP00000042938 ENSGGOP00000043030 ENSGGOP00000043030
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIM1SIM bHLH transcription factor 1. (767 aa)
CENPVL3Centromere protein V like 3. (287 aa)
CCDC36Coiled-coil domain containing 36. (595 aa)
ENSGGOP00000043851G-patch domain-containing protein. (223 aa)
ENSGGOP00000044043Uncharacterized protein. (100 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
XPO1Exportin 1. (1071 aa)
CENPOCentromere protein O. (300 aa)
NDE1NudE neurodevelopment protein 1. (335 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (356 aa)
ENSGGOP00000044777Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (140 aa)
DCTN2Dynactin subunit 2. (427 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (745 aa)
SMC2Structural maintenance of chromosomes protein. (1197 aa)
MEI4Meiotic double-stranded break formation protein 4. (385 aa)
TEX11Testis expressed 11. (940 aa)
HORMAD1HORMA domain containing 1. (394 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1094 aa)
ENSGGOP00000047617SKA2 domain-containing protein. (92 aa)
SYCP3Synaptonemal complex protein 3. (242 aa)
HORMAD2HORMA domain containing 2. (307 aa)
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (687 aa)
ENSGGOP00000050061Uncharacterized protein. (106 aa)
ENSGGOP00000050156DUF4187 domain-containing protein. (83 aa)
ENSGGOP00000050356Replication timing regulatory factor 1. (2281 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
LRPPRCPPR_long domain-containing protein. (407 aa)
ENSGGOP00000051819Protein kinase domain-containing protein. (421 aa)
MEIKINMeiotic kinetochore factor. (373 aa)
G3RRD3_GORGORRM domain-containing protein. (249 aa)
SPAG5Sperm associated antigen 5. (1198 aa)
G3RT90_GORGOHORMA domain-containing protein. (143 aa)
RNF212Ring finger protein 212. (297 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
CENPQCentromere protein Q. (268 aa)
CNTD1Uncharacterized protein. (247 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (3052 aa)
RGS12Regulator of G protein signaling 12. (1368 aa)
KNL1Kinetochore scaffold 1. (2342 aa)
GLYATL3Glycine-N-acyltransferase like 3. (288 aa)
PRDM9PR/SET domain 9. (822 aa)
CENPVL2Centromere protein V like 2. (282 aa)
CENPVL1Centromere protein V like 1. (272 aa)
WAPLWAPL cohesin release factor. (1190 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
FAM43BFamily with sequence similarity 43 member B. (334 aa)
G3S5H5_GORGOUncharacterized protein. (838 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
BANF1Uncharacterized protein. (89 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (170 aa)
SYCE2Uncharacterized protein. (126 aa)
MAGEB6MAGE family member B6. (407 aa)
ZIM3Zinc finger imprinted 3. (472 aa)
FAM43AFamily with sequence similarity 43 member A. (423 aa)
STAG3Stromal antigen 3. (1221 aa)
ZNF287Zinc finger protein 287. (761 aa)
CENPACentromere protein A. (140 aa)
CENPUCentromere protein U. (421 aa)
CDT1Chromatin licensing and DNA replication factor 1. (552 aa)
PHF2PHD finger protein 2. (1100 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (559 aa)
L3MBTL1Uncharacterized protein. (837 aa)
ESRRBEstrogen related receptor beta. (508 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
ENSGGOP00000029373Uncharacterized protein. (89 aa)
SIM2SIM bHLH transcription factor 2. (667 aa)
TTNTitin. (32000 aa)
MEAF6MYST/Esa1 associated factor 6. (171 aa)
ENSGGOP00000031048MAGE family member B4. (346 aa)
MDP1Magnesium dependent phosphatase 1. (164 aa)
ENSGGOP00000031463Peptidylprolyl isomerase. (101 aa)
FKBP6Peptidylprolyl isomerase. (327 aa)
ENSGGOP00000032803MutS homolog 4. (844 aa)
NCAPGNon-SMC condensin I complex subunit G. (1055 aa)
SLC39A1Solute carrier family 39 member 1. (324 aa)
ENSGGOP00000034934Uncharacterized protein. (76 aa)
ENSGGOP00000035259Structural maintenance of chromosomes 1A. (1096 aa)
ENSGGOP00000035777Baculoviral IAP repeat containing 5. (165 aa)
ENSGGOP00000035879RRM domain-containing protein. (251 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1058 aa)
STAG1Stromal antigen 1. (1258 aa)
SGO2Shugoshin 2. (1266 aa)
ENSGGOP00000038116Uncharacterized protein. (72 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (429 aa)
SYCP2Synaptonemal complex protein 2. (1530 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
DYNLL1Dynein light chain. (89 aa)
ENSGGOP00000040771Uncharacterized protein. (173 aa)
ENSGGOP00000040881Dynein light chain. (72 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (668 aa)
SKA3Spindle and kinetochore associated complex subunit 3. (412 aa)
G3RF65_GORGOProtein phosphatase 1 regulatory subunit. (989 aa)
G3RHR8_GORGOSynaptonemal complex protein 1. (942 aa)
HMGB2High mobility group box 2. (208 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (497 aa)
REC8REC8 meiotic recombination protein. (547 aa)
CCDC155Coiled-coil domain containing 155. (562 aa)
MLH1MutL homolog 1. (756 aa)
SMC5SMC_N domain-containing protein. (1101 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
CHEK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
G3RP17_GORGOStructural maintenance of chromosomes protein. (1175 aa)
FBXO28F-box protein 28. (368 aa)
RAD21L1RAD21 cohesin complex component like 1. (556 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (293 aa)
CENPTCentromere protein T. (561 aa)
CTCFCCCTC-binding factor. (727 aa)
SHOC1Shortage in chiasmata 1. (1408 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
REC114REC114 meiotic recombination protein. (265 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
G3RCP0_GORGOHSF_DOMAIN domain-containing protein. (527 aa)
SYCP2LSynaptonemal complex protein 2 like. (812 aa)
RSKRRibosomal protein S6 kinase related. (410 aa)
G3RA54_GORGOCentromere protein I. (669 aa)
MAGEB2MAGE family member B2. (319 aa)
RAD21RAD21 cohesin complex component. (631 aa)
NRG3Neuregulin 3. (720 aa)
G3R6L0_GORGOMAGE family member B10. (347 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
G3R6C8_GORGOCentromere protein W. (103 aa)
G3R5X1_GORGONon-SMC condensin II complex subunit H2. (546 aa)
G3R5V1_GORGOZinc finger protein 276. (614 aa)
BOD1Biorientation of chromosomes in cell division 1. (185 aa)
G3R5R0_GORGOPolyamine modulated factor 1. (207 aa)
G3R534_GORGONon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (328 aa)
C14H14orf39Chromosome 14 open reading frame 39. (587 aa)
MIS12MIS12 kinetochore complex component. (205 aa)
BRD4Bromodomain containing 4. (1362 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
G3R3B3_GORGOCell cycle checkpoint control protein; Belongs to the rad9 family. (383 aa)
MTBPMDM2 binding protein. (904 aa)
CENPCCentromere protein C. (943 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1401 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
TTKTTK protein kinase. (856 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (331 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (247 aa)
BLMBLM RecQ like helicase. (1415 aa)
G3QX71_GORGOUncharacterized protein. (91 aa)
HUS1BCheckpoint protein; Belongs to the HUS1 family. (278 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
ZWINTZW10 interacting kinetochore protein. (279 aa)
G3QW19_GORGOUncharacterized protein. (423 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (673 aa)
G3QV95_GORGOSGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (365 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
MIS18BP1MIS18 binding protein 1. (1132 aa)
C1H1orf146Chromosome 1 open reading frame 146. (180 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
SGO1Shugoshin 1. (527 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (373 aa)
TRAPPC12Trafficking protein particle complex 12. (739 aa)
NEK2NIMA related kinase 2. (445 aa)
G3QRL9_GORGOMAGE family member B1. (347 aa)
CENPKCentromere protein K. (269 aa)
RAD1RAD1 checkpoint DNA exonuclease. (282 aa)
MKI67Marker of proliferation Ki-67. (3253 aa)
STAG2Stromal antigen 2. (1268 aa)
SMC6Structural maintenance of chromosomes 6. (1064 aa)
TPRTranslocated promoter region, nuclear basket protein. (2363 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
SYCE1Synaptonemal complex central element protein 1. (351 aa)
G3QK51_GORGOCentromere protein N. (315 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
HJURPHolliday junction recognition protein. (743 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
CENPFCentromere protein F. (3057 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1068 aa)
G3QIE9_GORGOUncharacterized protein. (202 aa)
G3QI01_GORGOCAP-Gly domain containing linker protein 1. (1438 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2120 aa)
CENPHCentromere protein H. (247 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
G3RED9_GORGODNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
RASSF2Ras association domain family member 2. (326 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
FBXO28-2F-box protein 28. (179 aa)
ENSGGOP00000042938Checkpoint protein; Belongs to the HUS1 family. (273 aa)
ENSGGOP00000043030Serine/threonine-protein kinase PLK. (624 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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