5 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (277 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (446 aa)
	DIABLO	Uncharacterized protein. (166 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BCL2	ENSGGOP00000035421	ENSGGOP00000000778	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 apoptosis regulator.	0.913
APAF1	CASP3	ENSGGOP00000035421	ENSGGOP00000021659	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 3; Belongs to the peptidase C14A family.	0.995
APAF1	CASP9	ENSGGOP00000035421	ENSGGOP00000001932	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	DIABLO	ENSGGOP00000035421	ENSGGOP00000005240	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.914
BCL2	APAF1	ENSGGOP00000000778	ENSGGOP00000035421	BCL2 apoptosis regulator.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.913
BCL2	CASP3	ENSGGOP00000000778	ENSGGOP00000021659	BCL2 apoptosis regulator.	Caspase 3; Belongs to the peptidase C14A family.	0.868
BCL2	CASP9	ENSGGOP00000000778	ENSGGOP00000001932	BCL2 apoptosis regulator.	Caspase 9; Belongs to the peptidase C14A family.	0.731
BCL2	DIABLO	ENSGGOP00000000778	ENSGGOP00000005240	BCL2 apoptosis regulator.	Uncharacterized protein.	0.715
CASP3	APAF1	ENSGGOP00000021659	ENSGGOP00000035421	Caspase 3; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.995
CASP3	BCL2	ENSGGOP00000021659	ENSGGOP00000000778	Caspase 3; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator.	0.868
CASP3	CASP9	ENSGGOP00000021659	ENSGGOP00000001932	Caspase 3; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.997
CASP3	DIABLO	ENSGGOP00000021659	ENSGGOP00000005240	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.776
CASP9	APAF1	ENSGGOP00000001932	ENSGGOP00000035421	Caspase 9; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
CASP9	BCL2	ENSGGOP00000001932	ENSGGOP00000000778	Caspase 9; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator.	0.731
CASP9	CASP3	ENSGGOP00000001932	ENSGGOP00000021659	Caspase 9; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.997
CASP9	DIABLO	ENSGGOP00000001932	ENSGGOP00000005240	Caspase 9; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.817
DIABLO	APAF1	ENSGGOP00000005240	ENSGGOP00000035421	Uncharacterized protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.914
DIABLO	BCL2	ENSGGOP00000005240	ENSGGOP00000000778	Uncharacterized protein.	BCL2 apoptosis regulator.	0.715
DIABLO	CASP3	ENSGGOP00000005240	ENSGGOP00000021659	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.776
DIABLO	CASP9	ENSGGOP00000005240	ENSGGOP00000001932	Uncharacterized protein.	Caspase 9; Belongs to the peptidase C14A family.	0.817