(22 nodes) Sin3-type complex network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SAP30L	SAP30 like. (183 aa)
	SAP30	Sin3A associated protein 30. (220 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	BRMS1L	BRMS1 like transcriptional repressor. (323 aa)
	SIN3B	SIN3 transcription regulator family member B. (1153 aa)
	SUDS3	SDS3 homolog, SIN3A corepressor complex component. (328 aa)
	HDAC8	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	TET1	Tet methylcytosine dioxygenase 1. (2136 aa)
	PHF12	PHD finger protein 12. (1004 aa)
	ING1	Inhibitor of growth protein. (421 aa)
	SINHCAF	Uncharacterized protein. (221 aa)
	SAP130	Sin3A associated protein 130. (1083 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	ARID4B	AT-rich interaction domain 4B. (1312 aa)
	ENSGGOP00000033437	Uncharacterized protein. (104 aa)
	ENSGGOP00000035022	Uncharacterized protein. (197 aa)
	SIN3A	Uncharacterized protein. (154 aa)
	BRMS1	Uncharacterized protein. (377 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2564 aa)
	ENSGGOP00000042808	Uncharacterized protein. (189 aa)
	ING2	Inhibitor of growth protein. (280 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4B	BRMS1	ENSGGOP00000024418	ENSGGOP00000037195	AT-rich interaction domain 4B.	Uncharacterized protein.	0.967
ARID4B	BRMS1L	ENSGGOP00000024418	ENSGGOP00000006250	AT-rich interaction domain 4B.	BRMS1 like transcriptional repressor.	0.971
ARID4B	ENSGGOP00000033437	ENSGGOP00000024418	ENSGGOP00000033437	AT-rich interaction domain 4B.	Uncharacterized protein.	0.980
ARID4B	ENSGGOP00000035022	ENSGGOP00000024418	ENSGGOP00000035022	AT-rich interaction domain 4B.	Uncharacterized protein.	0.636
ARID4B	ENSGGOP00000042808	ENSGGOP00000024418	ENSGGOP00000042808	AT-rich interaction domain 4B.	Uncharacterized protein.	0.636
ARID4B	HDAC1	ENSGGOP00000024418	ENSGGOP00000011454	AT-rich interaction domain 4B.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.955
ARID4B	HDAC2	ENSGGOP00000024418	ENSGGOP00000005320	AT-rich interaction domain 4B.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.955
ARID4B	HDAC3	ENSGGOP00000024418	ENSGGOP00000015976	AT-rich interaction domain 4B.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
ARID4B	HDAC8	ENSGGOP00000024418	ENSGGOP00000011306	AT-rich interaction domain 4B.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
ARID4B	ING1	ENSGGOP00000024418	ENSGGOP00000012689	AT-rich interaction domain 4B.	Inhibitor of growth protein.	0.831
ARID4B	ING2	ENSGGOP00000024418	ENSGGOP00000049820	AT-rich interaction domain 4B.	Inhibitor of growth protein.	0.805
ARID4B	PHF12	ENSGGOP00000024418	ENSGGOP00000012040	AT-rich interaction domain 4B.	PHD finger protein 12.	0.839
ARID4B	SAP130	ENSGGOP00000024418	ENSGGOP00000015694	AT-rich interaction domain 4B.	Sin3A associated protein 130.	0.975
ARID4B	SAP30	ENSGGOP00000024418	ENSGGOP00000004979	AT-rich interaction domain 4B.	Sin3A associated protein 30.	0.980
ARID4B	SAP30L	ENSGGOP00000024418	ENSGGOP00000004357	AT-rich interaction domain 4B.	SAP30 like.	0.931
ARID4B	SETD2	ENSGGOP00000024418	ENSGGOP00000041243	AT-rich interaction domain 4B.	SET domain containing 2, histone lysine methyltransferase.	0.600
ARID4B	SIN3A	ENSGGOP00000024418	ENSGGOP00000035548	AT-rich interaction domain 4B.	Uncharacterized protein.	0.943
ARID4B	SIN3B	ENSGGOP00000024418	ENSGGOP00000009306	AT-rich interaction domain 4B.	SIN3 transcription regulator family member B.	0.936
ARID4B	SINHCAF	ENSGGOP00000024418	ENSGGOP00000015105	AT-rich interaction domain 4B.	Uncharacterized protein.	0.636
ARID4B	SUDS3	ENSGGOP00000024418	ENSGGOP00000010734	AT-rich interaction domain 4B.	SDS3 homolog, SIN3A corepressor complex component.	0.982