STRINGSTRING
KMT2A KMT2A G3QH03_GORGO G3QH03_GORGO PHF20 PHF20 TEX10 TEX10 TAF4 TAF4 TAF6 TAF6 MEN1 MEN1 TAF7L TAF7L PELP1 PELP1 HCFC1 HCFC1 SENP3 SENP3 MXD3 MXD3 RNF2 RNF2 E2F6 E2F6 MAX MAX CHD8 CHD8 TAF1 TAF1 C17H17orf49 C17H17orf49
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3982 aa)
G3QH03_GORGOMAX dimerization protein MGA. (3006 aa)
PHF20PHD finger protein 20. (1012 aa)
TEX10Testis expressed 10. (929 aa)
TAF4TAFH domain-containing protein. (635 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
MEN1Menin 1. (615 aa)
TAF7LTATA-box binding protein associated factor 7 like. (461 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1180 aa)
HCFC1Host cell factor C1. (2035 aa)
SENP3ULP_PROTEASE domain-containing protein. (574 aa)
MXD3BHLH domain-containing protein. (387 aa)
RNF2Ring finger protein 2. (336 aa)
E2F6E2F transcription factor 6. (281 aa)
MAXMYC associated factor X. (148 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
C17H17orf49Uncharacterized protein. (219 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (28%) [HD]