(11 nodes) CHD-type complex network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	MBD3L1	Methyl-CpG binding domain protein 3 like 1. (194 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	G3R9K9_GORGO	MBD domain-containing protein. (223 aa)
	CHD3	Chromodomain helicase DNA binding protein 3. (2000 aa)
	MTA2	Metastasis associated 1 family member 2. (673 aa)
	CHD4	Uncharacterized protein. (1912 aa)
	CHD5	Chromodomain helicase DNA binding protein 5. (1957 aa)
	MTA3	Metastasis associated 1 family member 3. (594 aa)
	GATAD2A	GATA zinc finger domain containing 2A. (635 aa)
	MTA1	Metastasis associated 1. (734 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	CHD4	ENSGGOP00000013179	ENSGGOP00000018333	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.984
CHD3	CHD5	ENSGGOP00000013179	ENSGGOP00000031639	Chromodomain helicase DNA binding protein 3.	Chromodomain helicase DNA binding protein 5.	0.607
CHD3	G3R9K9_GORGO	ENSGGOP00000013179	ENSGGOP00000012093	Chromodomain helicase DNA binding protein 3.	MBD domain-containing protein.	0.940
CHD3	GATAD2A	ENSGGOP00000013179	ENSGGOP00000045410	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2A.	0.992
CHD3	HDAC1	ENSGGOP00000013179	ENSGGOP00000011454	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.987
CHD3	HDAC2	ENSGGOP00000013179	ENSGGOP00000005320	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.987
CHD3	MBD3L1	ENSGGOP00000013179	ENSGGOP00000008082	Chromodomain helicase DNA binding protein 3.	Methyl-CpG binding domain protein 3 like 1.	0.901
CHD3	MTA1	ENSGGOP00000013179	ENSGGOP00000048346	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.990
CHD3	MTA2	ENSGGOP00000013179	ENSGGOP00000013241	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.990
CHD3	MTA3	ENSGGOP00000013179	ENSGGOP00000037680	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 3.	0.981
CHD4	CHD3	ENSGGOP00000018333	ENSGGOP00000013179	Uncharacterized protein.	Chromodomain helicase DNA binding protein 3.	0.984
CHD4	CHD5	ENSGGOP00000018333	ENSGGOP00000031639	Uncharacterized protein.	Chromodomain helicase DNA binding protein 5.	0.740
CHD4	G3R9K9_GORGO	ENSGGOP00000018333	ENSGGOP00000012093	Uncharacterized protein.	MBD domain-containing protein.	0.973
CHD4	GATAD2A	ENSGGOP00000018333	ENSGGOP00000045410	Uncharacterized protein.	GATA zinc finger domain containing 2A.	0.991
CHD4	HDAC1	ENSGGOP00000018333	ENSGGOP00000011454	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.998
CHD4	HDAC2	ENSGGOP00000018333	ENSGGOP00000005320	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.996
CHD4	MBD3L1	ENSGGOP00000018333	ENSGGOP00000008082	Uncharacterized protein.	Methyl-CpG binding domain protein 3 like 1.	0.854
CHD4	MTA1	ENSGGOP00000018333	ENSGGOP00000048346	Uncharacterized protein.	Metastasis associated 1.	0.995
CHD4	MTA2	ENSGGOP00000018333	ENSGGOP00000013241	Uncharacterized protein.	Metastasis associated 1 family member 2.	0.996
CHD4	MTA3	ENSGGOP00000018333	ENSGGOP00000037680	Uncharacterized protein.	Metastasis associated 1 family member 3.	0.988