STRINGSTRING
TRMT13 TRMT13 SLU7 SLU7 PRPF8 PRPF8 MEPCE MEPCE TXNL4A TXNL4A ENSGGOP00000035553 ENSGGOP00000035553 PPIH PPIH ENSGGOP00000036541 ENSGGOP00000036541 ENSGGOP00000037336 ENSGGOP00000037336 ENSGGOP00000038952 ENSGGOP00000038952 ENSGGOP00000040319 ENSGGOP00000040319 ENSGGOP00000041470 ENSGGOP00000041470 ENSGGOP00000041513 ENSGGOP00000041513 CLNS1A CLNS1A LARP7 LARP7 ENSGGOP00000044449 ENSGGOP00000044449 SNRNP200 SNRNP200 LSM2 LSM2 ZMAT2 ZMAT2 SF3B4 SF3B4 SNRPN SNRPN PRPF38A PRPF38A SNRPB2 SNRPB2 SF3B3 SF3B3 SNRPD2 SNRPD2 PRPF40B PRPF40B SF3B5 SF3B5 USP39 USP39 G3QFU4_GORGO G3QFU4_GORGO SNRPF SNRPF PHF5A PHF5A G3QEP5_GORGO G3QEP5_GORGO ENSGGOP00000052255 ENSGGOP00000052255 ENSGGOP00000052276 ENSGGOP00000052276 LUC7L LUC7L ENSGGOP00000052403 ENSGGOP00000052403 TMIGD2 TMIGD2 GEMIN6 GEMIN6 ENSGGOP00000045291 ENSGGOP00000045291 ENSGGOP00000045369 ENSGGOP00000045369 ENSGGOP00000045752 ENSGGOP00000045752 PRPF4 PRPF4 ENSGGOP00000045899 ENSGGOP00000045899 LSM5 LSM5 ENSGGOP00000046986 ENSGGOP00000046986 LSM4 LSM4 SNRPE SNRPE GEMIN7 GEMIN7 ENSGGOP00000048443 ENSGGOP00000048443 ENSGGOP00000050193 ENSGGOP00000050193 ENSGGOP00000050803 ENSGGOP00000050803 ENSGGOP00000050996 ENSGGOP00000050996 G3RWU8_GORGO G3RWU8_GORGO RBM42 RBM42 MMP10 MMP10 G3RT30_GORGO G3RT30_GORGO SNRNP40 SNRNP40 SNRPG SNRPG GEMIN8 GEMIN8 PRPF6 PRPF6 G3RKL5_GORGO G3RKL5_GORGO G3RJ69_GORGO G3RJ69_GORGO ZNF608 ZNF608 SNRPD3 SNRPD3 DDX20 DDX20 DDX23 DDX23 HEXIM1 HEXIM1 CD2BP2 CD2BP2 SNRNP48 SNRNP48 G3RBJ7_GORGO G3RBJ7_GORGO SF3A1 SF3A1 SART3 SART3 G3R566_GORGO G3R566_GORGO LSM7 LSM7 LSM3 LSM3 AAR2 AAR2 RBMX2 RBMX2 PDE6C PDE6C SNRPA1 SNRPA1 PRPF40A PRPF40A LSM11 LSM11 SNRPB SNRPB G3S6E7_GORGO G3S6E7_GORGO G3S6R0_GORGO G3S6R0_GORGO SMN1 SMN1 LSM1 LSM1 GEMIN4 GEMIN4 G3SA52_GORGO G3SA52_GORGO HTATSF1 HTATSF1 SF3B2 SF3B2 SNRNP70 SNRNP70 G3SGZ6_GORGO G3SGZ6_GORGO G3SHH7_GORGO G3SHH7_GORGO G3SIA3_GORGO G3SIA3_GORGO LUC7L3 LUC7L3 SNIP1 SNIP1 SNRPD1 SNRPD1 ENSGGOP00000030103 ENSGGOP00000030103 LSM6 LSM6 SF3B6 SF3B6 ENSGGOP00000030598 ENSGGOP00000030598 ENSGGOP00000031230 ENSGGOP00000031230 ENSGGOP00000031775 ENSGGOP00000031775 DDX46 DDX46 SF3A3 SF3A3 SNRPD1-2 SNRPD1-2 ENSGGOP00000032634 ENSGGOP00000032634 C3H3orf49 C3H3orf49 CCDC84 CCDC84 ENSGGOP00000033609 ENSGGOP00000033609 LSM8 LSM8 ENSGGOP00000035072 ENSGGOP00000035072 G3R386_GORGO G3R386_GORGO SART1 SART1 SF3A2 SF3A2 DDX39B DDX39B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRMT13tRNA methyltransferase 13 homolog. (481 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
MEPCEMethylphosphate capping enzyme. (689 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
ENSGGOP00000035553Sm domain-containing protein. (73 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
ENSGGOP00000036541Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (71 aa)
ENSGGOP00000037336Small nuclear ribonucleoprotein-associated protein. (199 aa)
ENSGGOP00000038952GYF domain-containing protein. (174 aa)
ENSGGOP00000040319Sm domain-containing protein. (78 aa)
ENSGGOP00000041470Splicing factor 3b subunit 1. (1268 aa)
ENSGGOP00000041513Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
LARP7Uncharacterized protein. (589 aa)
ENSGGOP00000044449Uncharacterized protein. (533 aa)
SNRNP200Uncharacterized protein. (2136 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (244 aa)
PRPF38APre-mRNA processing factor 38A. (312 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
PRPF40BPre-mRNA processing factor 40 homolog B. (892 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
USP39Ubiquitin specific peptidase 39. (565 aa)
G3QFU4_GORGOSmall nuclear ribonucleoprotein polypeptide A. (282 aa)
SNRPFSm domain-containing protein. (86 aa)
PHF5APHD finger protein 5A. (110 aa)
G3QEP5_GORGOSmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (61 aa)
ENSGGOP00000052255Uncharacterized protein. (87 aa)
ENSGGOP00000052276Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
LUC7LLUC7 like. (361 aa)
ENSGGOP00000052403Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (67 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (281 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
ENSGGOP00000045291LRRcap domain-containing protein. (255 aa)
ENSGGOP00000045369WD_REPEATS_REGION domain-containing protein. (326 aa)
ENSGGOP00000045752RRM domain-containing protein. (470 aa)
PRPF4Pre-mRNA processing factor 4. (539 aa)
ENSGGOP00000045899Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (272 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
ENSGGOP00000046986Uncharacterized protein. (97 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (238 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
GEMIN7Gem nuclear organelle associated protein 7. (131 aa)
ENSGGOP00000048443Helicase C-terminal domain-containing protein. (558 aa)
ENSGGOP00000050193Sm domain-containing protein. (65 aa)
ENSGGOP00000050803Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (87 aa)
ENSGGOP00000050996Uncharacterized protein. (413 aa)
G3RWU8_GORGOUncharacterized protein. (428 aa)
RBM42RNA binding motif protein 42. (480 aa)
MMP10Matrix metallopeptidase 10. (476 aa)
G3RT30_GORGOSmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
GEMIN8Gem nuclear organelle associated protein 8. (242 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
G3RKL5_GORGOGem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (242 aa)
G3RJ69_GORGORRM domain-containing protein. (312 aa)
ZNF608Zinc finger protein 608. (1512 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
DDX20DEAD-box helicase 20. (824 aa)
DDX23DEAD-box helicase 23. (820 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (341 aa)
SNRNP48Small nuclear ribonucleoprotein U11/U12 subunit 48. (339 aa)
G3RBJ7_GORGOPre-mRNA processing factor 3. (580 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (963 aa)
G3R566_GORGOGem nuclear organelle associated protein 5. (1286 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
AAR2AAR2 splicing factor. (398 aa)
RBMX2RNA binding motif protein X-linked 2. (322 aa)
PDE6CPhosphodiesterase. (858 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (930 aa)
LSM11LSM11, U7 small nuclear RNA associated. (360 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
G3S6E7_GORGOChromosome 19 open reading frame 54. (351 aa)
G3S6R0_GORGOUncharacterized protein. (297 aa)
SMN1Survival of motor neuron 1, telomeric. (262 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1058 aa)
G3SA52_GORGORRM domain-containing protein. (290 aa)
HTATSF1HIV-1 Tat specific factor 1. (755 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (437 aa)
G3SGZ6_GORGOUncharacterized protein. (120 aa)
G3SHH7_GORGOTudor domain-containing protein. (225 aa)
G3SIA3_GORGOADP ribosylation factor guanine nucleotide exchange factor 1. (1745 aa)
LUC7L3LUC7 like 3 pre-mRNA splicing factor. (477 aa)
SNIP1Smad nuclear interacting protein 1. (396 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (120 aa)
ENSGGOP00000030103Uncharacterized protein. (178 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
ENSGGOP00000030598Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (62 aa)
ENSGGOP00000031230Uncharacterized protein. (379 aa)
ENSGGOP00000031775RRM domain-containing protein. (202 aa)
DDX46DEAD-box helicase 46. (1031 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
SNRPD1-2Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
ENSGGOP00000032634SEC63 domain-containing protein. (279 aa)
C3H3orf49Chromosome 3 open reading frame 49. (292 aa)
CCDC84Coiled-coil domain containing 84. (342 aa)
ENSGGOP00000033609Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (64 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
ENSGGOP00000035072WD_REPEATS_REGION domain-containing protein. (345 aa)
G3R386_GORGOSerine/threonine kinase receptor associated protein. (335 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
DDX39BDExD-box helicase 39B. (428 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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