(16 nodes) Netrin module, non-TIMP type network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3R8C0_GORGO	Uncharacterized protein. (346 aa)
	PCOLCE	Procollagen C-endopeptidase enhancer. (449 aa)
	C5	Complement C5. (1646 aa)
	FRZB	Frizzled related protein. (325 aa)
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	ENSGGOP00000044488	Uncharacterized protein. (1750 aa)
	PCOLCE2	Procollagen C-endopeptidase enhancer 2. (417 aa)
	C3	Complement C3. (1663 aa)
	NTN3	Netrin 3. (580 aa)
	SFRP4	Secreted frizzled related protein 4. (368 aa)
	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
	ADAMTSL5	ADAMTS like 5. (471 aa)
	NTN4	Netrin 4. (628 aa)
	NTN5	Netrin 5. (491 aa)
	SFRP5	Secreted frizzled related protein 5. (317 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3	C5	ENSGGOP00000024983	ENSGGOP00000002253	Complement C3.	Complement C5.	0.977
C3	ENSGGOP00000044488	ENSGGOP00000024983	ENSGGOP00000044488	Complement C3.	Uncharacterized protein.	0.960
C3	NTN5	ENSGGOP00000024983	ENSGGOP00000012693	Complement C3.	Netrin 5.	0.421
C5	C3	ENSGGOP00000002253	ENSGGOP00000024983	Complement C5.	Complement C3.	0.977
C5	ENSGGOP00000044488	ENSGGOP00000002253	ENSGGOP00000044488	Complement C5.	Uncharacterized protein.	0.654
ENSGGOP00000044488	C3	ENSGGOP00000044488	ENSGGOP00000024983	Uncharacterized protein.	Complement C3.	0.960
ENSGGOP00000044488	C5	ENSGGOP00000044488	ENSGGOP00000002253	Uncharacterized protein.	Complement C5.	0.654
NTN5	C3	ENSGGOP00000012693	ENSGGOP00000024983	Netrin 5.	Complement C3.	0.421