STRINGSTRING
G3QM44_GORGO G3QM44_GORGO OTOF OTOF SYTL1 SYTL1 C2CD3 C2CD3 G3QDN8_GORGO G3QDN8_GORGO RASAL3 RASAL3 GAK GAK PLCB2 PLCB2 PTEN PTEN RASAL2 RASAL2 SYTL4 SYTL4 C2CD4C C2CD4C G3QGX6_GORGO G3QGX6_GORGO SYTL2 SYTL2 PRF1 PRF1 SYTL5 SYTL5 G3QJW7_GORGO G3QJW7_GORGO ASCC3 ASCC3 SYDE2 SYDE2 UVRAG UVRAG PRKCD PRKCD TNS3 TNS3 ENSGGOP00000052063 ENSGGOP00000052063 WWC3 WWC3 SYTL3 SYTL3 SYT17 SYT17 RASA3 RASA3 UNC13B UNC13B ENSGGOP00000048443 ENSGGOP00000048443 MCTP2 MCTP2 SYT6 SYT6 ENSGGOP00000046354 ENSGGOP00000046354 PLCL2 PLCL2 ESYT1 ESYT1 INPP4B INPP4B DNAJC6 DNAJC6 DOCK8 DOCK8 PLCB1 PLCB1 PIK3C2G PIK3C2G PKN2 PKN2 PIK3C2B PIK3C2B DOCK9 DOCK9 ENSGGOP00000041027 ENSGGOP00000041027 RASA1 RASA1 C2CD2 C2CD2 SYT10 SYT10 DOCK10 DOCK10 TNS1 TNS1 BAIAP3 BAIAP3 SYT3 SYT3 ENSGGOP00000037088 ENSGGOP00000037088 ENSGGOP00000036870 ENSGGOP00000036870 PIK3C3 PIK3C3 PRKCG PRKCG PLCZ1 PLCZ1 ENSGGOP00000034857 ENSGGOP00000034857 ITSN1 ITSN1 NEDD4 NEDD4 HECW1 HECW1 NEDD4L NEDD4L PLCL1 PLCL1 ENSGGOP00000032634 ENSGGOP00000032634 PLCB4 PLCB4 SYT11 SYT11 DAB2IP DAB2IP C2CD5 C2CD5 ENSGGOP00000030704 ENSGGOP00000030704 CPNE8 CPNE8 DOCK7 DOCK7 G3SKN5_GORGO G3SKN5_GORGO CADPS2 CADPS2 UNC13D UNC13D CC2D1B CC2D1B C2CD4B C2CD4B PLCG2 PLCG2 G3SE74_GORGO G3SE74_GORGO FER1L5 FER1L5 PIK3CG PIK3CG SYT13 SYT13 G3S4L5_GORGO G3S4L5_GORGO FER1L6 FER1L6 SYT1 SYT1 WWC2 WWC2 DOCK3 DOCK3 PLA2G4F PLA2G4F RPH3A RPH3A G3RZG6_GORGO G3RZG6_GORGO CPNE3 CPNE3 WWC1 WWC1 C2CD4D C2CD4D G3RXY5_GORGO G3RXY5_GORGO G3RXD2_GORGO G3RXD2_GORGO CCDC33 CCDC33 INPP4A INPP4A G3RUH1_GORGO G3RUH1_GORGO MYOF MYOF RPGRIP1L RPGRIP1L PIK3C2A PIK3C2A G3RNB7_GORGO G3RNB7_GORGO RAB11FIP5 RAB11FIP5 SMURF1 SMURF1 G3RM60_GORGO G3RM60_GORGO SYT9 SYT9 ABR ABR SYT16 SYT16 CPNE6 CPNE6 PRKCA PRKCA PKN1 PKN1 AIDA AIDA G3RGR1_GORGO G3RGR1_GORGO DOCK1 DOCK1 G3RG69_GORGO G3RG69_GORGO TNS2 TNS2 DOCK11 DOCK11 CPNE9 CPNE9 UNC13A UNC13A RIMS4 RIMS4 PRKCQ PRKCQ HECW2 HECW2 G3R9L0_GORGO G3R9L0_GORGO G3R9G9_GORGO G3R9G9_GORGO PLA2G4A PLA2G4A ESYT2 ESYT2 PLCB3 PLCB3 DOC2A DOC2A PRKCE PRKCE PLA2G4E PLA2G4E PKN3 PKN3 PLCD3 PLCD3 CPNE4 CPNE4 PRKCB PRKCB RPGRIP1 RPGRIP1 RASAL1 RASAL1 PLCH2 PLCH2 RIMS3 RIMS3 PIK3CB PIK3CB PLCH1 PLCH1 G3R274_GORGO G3R274_GORGO PIK3CA PIK3CA TC2N TC2N SYT5 SYT5 CEP120 CEP120 SYT8 SYT8 PRKCH PRKCH RGS3 RGS3 C2CD2L C2CD2L CAPN6 CAPN6 PLCG1 PLCG1 PLCE1 PLCE1 ITSN2 ITSN2 ITCH ITCH DYSF DYSF RAB11FIP2 RAB11FIP2 G3QW50_GORGO G3QW50_GORGO SMURF2 SMURF2 G3QVK7_GORGO G3QVK7_GORGO SYT4 SYT4 CPNE5 CPNE5 SNRNP200 SNRNP200 SYT2 SYT2 DOCK5 DOCK5 CC2D1A CC2D1A DOCK4 DOCK4 PCLO PCLO WWP2 WWP2 CPNE2 CPNE2 ESYT3 ESYT3 PLCD1 PLCD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QM44_GORGORegulating synaptic membrane exocytosis 1. (1692 aa)
OTOFOtoferlin. (1997 aa)
SYTL1Synaptotagmin like 1. (562 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2353 aa)
G3QDN8_GORGOPhospholipase A2. (781 aa)
RASAL3RAS protein activator like 3. (1011 aa)
GAKCyclin G associated kinase. (1302 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
RASAL2RAS protein activator like 2. (1280 aa)
SYTL4Synaptotagmin like 4. (673 aa)
C2CD4CC2 calcium dependent domain containing 4C. (421 aa)
G3QGX6_GORGOUncharacterized protein. (417 aa)
SYTL2Uncharacterized protein. (2223 aa)
PRF1Perforin 1. (555 aa)
SYTL5Synaptotagmin like 5. (752 aa)
G3QJW7_GORGOCoiled-coil and C2 domain containing 2A. (1620 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1194 aa)
UVRAGUV radiation resistance associated. (699 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
TNS3Tensin 3. (1445 aa)
ENSGGOP00000052063Unc-13 homolog C. (2090 aa)
WWC3WWC family member 3. (1201 aa)
SYTL3Synaptotagmin like 3. (610 aa)
SYT17Synaptotagmin 17. (474 aa)
RASA3RAS p21 protein activator 3. (821 aa)
UNC13BUncharacterized protein. (4296 aa)
ENSGGOP00000048443Helicase C-terminal domain-containing protein. (558 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (878 aa)
SYT6Uncharacterized protein. (539 aa)
ENSGGOP00000046354Phosphoinositide phospholipase C. (794 aa)
PLCL2Phosphoinositide phospholipase C. (1032 aa)
ESYT1Uncharacterized protein. (864 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (947 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2099 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
PKN2Protein kinase N2. (984 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1636 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2099 aa)
ENSGGOP00000041027Uncharacterized protein. (155 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
C2CD2C2 calcium dependent domain containing 2. (686 aa)
SYT10Synaptotagmin 10. (523 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2180 aa)
TNS1Tensin 1. (1735 aa)
BAIAP3BAI1 associated protein 3. (1187 aa)
SYT3Synaptotagmin 3. (590 aa)
ENSGGOP00000037088C2 domain-containing protein. (864 aa)
ENSGGOP00000036870Copine 7. (627 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (916 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
PLCZ1Phosphoinositide phospholipase C. (640 aa)
ENSGGOP00000034857Uncharacterized protein. (362 aa)
ITSN1Intersectin 1. (1721 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1575 aa)
NEDD4LUncharacterized protein. (1178 aa)
PLCL1Phosphoinositide phospholipase C. (1095 aa)
ENSGGOP00000032634SEC63 domain-containing protein. (279 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
SYT11Synaptotagmin 11. (431 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
C2CD5C2 calcium dependent domain containing 5. (1084 aa)
ENSGGOP00000030704Calpain 5; Belongs to the peptidase C2 family. (681 aa)
CPNE8Copine 8. (564 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2137 aa)
G3SKN5_GORGODedicator of cytokinesis 2; Belongs to the DOCK family. (1698 aa)
CADPS2Calcium dependent secretion activator 2. (1296 aa)
UNC13DUnc-13 homolog D. (1090 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (858 aa)
C2CD4BC2 calcium dependent domain containing 4B. (355 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
G3SE74_GORGOUncharacterized protein. (413 aa)
FER1L5Fer-1 like family member 5. (2093 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
SYT13Synaptotagmin 13. (426 aa)
G3S4L5_GORGOFer-1-like protein 4-like. (2033 aa)
FER1L6Fer-1 like family member 6. (1846 aa)
SYT1Synaptotagmin 1. (422 aa)
WWC2WW and C2 domain containing 2. (1147 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (1974 aa)
PLA2G4FPhospholipase A2. (849 aa)
RPH3ARabphilin 3A. (694 aa)
G3RZG6_GORGOUncharacterized protein. (476 aa)
CPNE3Copine 3. (537 aa)
WWC1WW and C2 domain containing 1. (1119 aa)
C2CD4DC2 calcium dependent domain containing 4D. (353 aa)
G3RXY5_GORGORAS p21 protein activator 2. (814 aa)
G3RXD2_GORGOUncharacterized protein. (287 aa)
CCDC33Coiled-coil domain containing 33. (755 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (977 aa)
G3RUH1_GORGOUncharacterized protein. (686 aa)
MYOFMyoferlin. (2061 aa)
RPGRIP1LRPGRIP1 like. (1269 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
G3RNB7_GORGOUncharacterized protein. (661 aa)
RAB11FIP5Uncharacterized protein. (1320 aa)
SMURF1E3 ubiquitin-protein ligase. (738 aa)
G3RM60_GORGOSynaptic Ras GTPase activating protein 1. (1329 aa)
SYT9Synaptotagmin 9. (491 aa)
ABRABR activator of RhoGEF and GTPase. (859 aa)
SYT16Synaptotagmin 16. (645 aa)
CPNE6Copine 6. (612 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PKN1Protein kinase N1. (948 aa)
AIDAAxin interactor, dorsalization associated. (306 aa)
G3RGR1_GORGOMultiple C2 and transmembrane domain containing 1. (866 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
G3RG69_GORGOSynaptotagmin 12. (421 aa)
TNS2Tensin 2. (1419 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2016 aa)
CPNE9Copine family member 9. (553 aa)
UNC13AUnc-13 homolog A. (1721 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (252 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
G3R9L0_GORGOPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
G3R9G9_GORGOToll interacting protein. (223 aa)
PLA2G4APhospholipase A2. (749 aa)
ESYT2Extended synaptotagmin 2. (809 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PLA2G4EPhospholipase A2. (868 aa)
PKN3Protein kinase N3. (889 aa)
PLCD3Phosphoinositide phospholipase C. (820 aa)
CPNE4Copine 4. (575 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
RPGRIP1RPGR interacting protein 1. (1287 aa)
RASAL1RAS protein activator like 1. (805 aa)
PLCH2Phosphoinositide phospholipase C. (1416 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
PLCH1Phosphoinositide phospholipase C. (1693 aa)
G3R274_GORGODedicator of cytokinesis 6; Belongs to the DOCK family. (2032 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TC2NTandem C2 domains, nuclear. (490 aa)
SYT5Synaptotagmin 5. (386 aa)
CEP120Centrosomal protein 120. (986 aa)
SYT8Synaptotagmin 8. (387 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
RGS3Regulator of G protein signaling 3. (1198 aa)
C2CD2LC2CD2 like. (707 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (641 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
PLCE1Phosphoinositide phospholipase C. (2300 aa)
ITSN2Intersectin 2. (1697 aa)
ITCHE3 ubiquitin-protein ligase. (903 aa)
DYSFDysferlin. (2119 aa)
RAB11FIP2RAB11 family interacting protein 2. (532 aa)
G3QW50_GORGOBCR activator of RhoGEF and GTPase. (1101 aa)
SMURF2E3 ubiquitin-protein ligase. (750 aa)
G3QVK7_GORGOUncharacterized protein. (1367 aa)
SYT4Synaptotagmin 4. (425 aa)
CPNE5Copine 5. (593 aa)
SNRNP200Uncharacterized protein. (2136 aa)
SYT2Synaptotagmin 2. (419 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (951 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1986 aa)
PCLOPiccolo presynaptic cytomatrix protein. (5111 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
CPNE2Copine 2. (488 aa)
ESYT3Extended synaptotagmin 3. (886 aa)
PLCD1Phosphoinositide phospholipase C. (777 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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