STRINGSTRING
DYNLL2 DYNLL2 G3S0Z1_GORGO G3S0Z1_GORGO CASP3 CASP3 G3S0J3_GORGO G3S0J3_GORGO G3RY92_GORGO G3RY92_GORGO BCL2L1 BCL2L1 STAT3 STAT3 APIP APIP BAK1 BAK1 YWHAZ YWHAZ G3RQE7_GORGO G3RQE7_GORGO G3RLK9_GORGO G3RLK9_GORGO SEPTIN1 SEPTIN1 G3RHQ4_GORGO G3RHQ4_GORGO UACA UACA G3RB29_GORGO G3RB29_GORGO G3RAA2_GORGO G3RAA2_GORGO NPVF NPVF SFN SFN BID BID BAX BAX AVEN AVEN XIAP XIAP SEPTIN4 SEPTIN4 AKT3 AKT3 BIRC8 BIRC8 BNIP5 BNIP5 G3QV30_GORGO G3QV30_GORGO YWHAH YWHAH DIABLO DIABLO GSDME GSDME TFDP1 TFDP1 YWHAB YWHAB TMEM198 TMEM198 E2F1 E2F1 BCL2L10 BCL2L10 C1QBP C1QBP CASP9 CASP9 YWHAQ YWHAQ BCL2 BCL2 CARD8 CARD8 MAPK10 MAPK10 ENSGGOP00000050539 ENSGGOP00000050539 TFDP2 TFDP2 ENSGGOP00000049412 ENSGGOP00000049412 MAPK8 MAPK8 BCL2L11 BCL2L11 ENSGGOP00000046735 ENSGGOP00000046735 BOK BOK CASP7 CASP7 YWHAG YWHAG ENSGGOP00000045023 ENSGGOP00000045023 ENSGGOP00000044990 ENSGGOP00000044990 TP63 TP63 ENSGGOP00000041462 ENSGGOP00000041462 BMF BMF ENSGGOP00000040881 ENSGGOP00000040881 DYNLL1 DYNLL1 YWHAE YWHAE MAPK1 MAPK1 BAD BAD PPP3R1 PPP3R1 ENSGGOP00000038104 ENSGGOP00000038104 APAF1 APAF1 GSDMB GSDMB ENSGGOP00000033404 ENSGGOP00000033404 AKT2 AKT2 ENSGGOP00000032522 ENSGGOP00000032522 ENSGGOP00000031996 ENSGGOP00000031996 TP53BP2 TP53BP2 ENSGGOP00000031130 ENSGGOP00000031130 ENSGGOP00000028898 ENSGGOP00000028898 CYCS CYCS G3SJ17_GORGO G3SJ17_GORGO G3SHM7_GORGO G3SHM7_GORGO G3SDM2_GORGO G3SDM2_GORGO PPP1R13B PPP1R13B NMT1 NMT1 G3SAG0_GORGO G3SAG0_GORGO G3S8N2_GORGO G3S8N2_GORGO G3S8L5_GORGO G3S8L5_GORGO TFDP3 TFDP3 SEPTIN5 SEPTIN5 G3S3D6_GORGO G3S3D6_GORGO MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYNLL2Uncharacterized protein. (183 aa)
G3S0Z1_GORGODynein light chain. (91 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
G3S0J3_GORGODUF4203 domain-containing protein. (106 aa)
G3RY92_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (242 aa)
BCL2L1BCL2 like 1. (233 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
G3RQE7_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
G3RLK9_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
G3RHQ4_GORGOTumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1403 aa)
G3RB29_GORGOGranzyme B; Belongs to the peptidase S1 family. (247 aa)
G3RAA2_GORGOProtein phosphatase 3 catalytic subunit gamma. (483 aa)
NPVFNeuropeptide VF precursor. (196 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
AVENApoptosis and caspase activation inhibitor. (358 aa)
XIAPUncharacterized protein. (371 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1012 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
BIRC8Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (236 aa)
BNIP5BCL2 interacting protein 5. (652 aa)
G3QV30_GORGOGasdermin D. (532 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
DIABLOUncharacterized protein. (166 aa)
GSDMEGasdermin E. (496 aa)
TFDP1Transcription factor. (411 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
TMEM198Transmembrane protein 198. (360 aa)
E2F1E2F transcription factor 1. (437 aa)
BCL2L10Uncharacterized protein. (204 aa)
C1QBPComplement C1q binding protein. (281 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CARD8Caspase recruitment domain family member 8. (522 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
ENSGGOP0000005053914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (211 aa)
TFDP2Transcription factor. (447 aa)
ENSGGOP00000049412Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (388 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (250 aa)
ENSGGOP0000004502314_3_3 domain-containing protein. (74 aa)
ENSGGOP0000004499014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (234 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ENSGGOP00000041462Uncharacterized protein. (164 aa)
BMFBcl2 modifying factor. (184 aa)
ENSGGOP00000040881Dynein light chain. (72 aa)
DYNLL1Dynein light chain. (89 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
BADBCL2 associated agonist of cell death. (168 aa)
PPP3R1Uncharacterized protein. (189 aa)
ENSGGOP0000003810414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (238 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
GSDMBGasdermin B. (416 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSGGOP0000003252214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa)
ENSGGOP00000031996Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (91 aa)
TP53BP2Tumor protein p53 binding protein 2. (1137 aa)
ENSGGOP00000031130Uncharacterized protein. (189 aa)
ENSGGOP0000002889814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
G3SJ17_GORGOUncharacterized protein. (100 aa)
G3SHM7_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa)
G3SDM2_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1090 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (521 aa)
G3SAG0_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
G3S8N2_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (91 aa)
G3S8L5_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (242 aa)
TFDP3Transcription factor. (405 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
G3S3D6_GORGO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (242 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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