STRINGSTRING
APC2 APC2 DSG1 DSG1 LMNA LMNA PRKCD PRKCD G3QLP4_GORGO G3QLP4_GORGO TMEM198 TMEM198 STK25 STK25 G3QPE1_GORGO G3QPE1_GORGO MAPT MAPT BCAP31 BCAP31 CLSPN CLSPN CDH1 CDH1 G3S0J3_GORGO G3S0J3_GORGO TJP3 TJP3 LMNB1 LMNB1 GAS2 GAS2 APC APC SATB1 SATB1 MAP2 MAP2 BCAP29 BCAP29 BMX BMX SCIN SCIN SH3GLB2 SH3GLB2 PRKCQ PRKCQ STK26 STK26 PKP1 PKP1 CAPG CAPG G3R656_GORGO G3R656_GORGO TJP2 TJP2 GSN GSN ROCK1 ROCK1 VIM VIM BIRC2 BIRC2 G3QWT5_GORGO G3QWT5_GORGO ACIN1 ACIN1 MAPT-2 MAPT-2 SPTAN1 SPTAN1 CASP6 CASP6 TJP1 TJP1 G3SAE6_GORGO G3SAE6_GORGO DSG2 DSG2 G3S3W3_GORGO G3S3W3_GORGO CTNNB1 CTNNB1 ENSGGOP00000047871 ENSGGOP00000047871 STK24 STK24 FNTA FNTA ENSGGOP00000046010 ENSGGOP00000046010 CASP7 CASP7 DSP DSP ENSGGOP00000038483 ENSGGOP00000038483 ENSGGOP00000036167 ENSGGOP00000036167 ENSGGOP00000033404 ENSGGOP00000033404 PTK2 PTK2 CASP3 CASP3 DSG3 DSG3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APC2APC regulator of WNT signaling pathway 2. (2289 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1050 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
G3QLP4_GORGOLamin B2; Belongs to the intermediate filament family. (532 aa)
TMEM198Transmembrane protein 198. (360 aa)
STK25Protein kinase domain-containing protein. (426 aa)
G3QPE1_GORGODrebrin like. (439 aa)
MAPTMicrotubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] (769 aa)
BCAP31B cell receptor associated protein 31. (313 aa)
CLSPNClaspin. (1335 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
G3S0J3_GORGODUF4203 domain-containing protein. (106 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (938 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
GAS2Growth arrest specific 2. (314 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
SATB1DNA-binding protein SATB. (795 aa)
MAP2Microtubule-associated protein. (1827 aa)
BCAP29B cell receptor associated protein 29. (330 aa)
BMXTyrosine-protein kinase. (675 aa)
SCINScinderin. (715 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (404 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
STK26Serine/threonine kinase 26. (438 aa)
PKP1Plakophilin 1. (747 aa)
CAPGCapping actin protein, gelsolin like. (348 aa)
G3R656_GORGOMARVEL domain-containing protein. (438 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1249 aa)
GSNGelsolin. (787 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
G3QWT5_GORGOAdducin 1. (691 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1302 aa)
MAPT-2Uncharacterized protein. (55 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
TJP1Uncharacterized protein. (336 aa)
G3SAE6_GORGOPlectin. (4554 aa)
DSG2Desmoglein 2. (1118 aa)
G3S3W3_GORGOUncharacterized protein. (321 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSGGOP00000047871Growth arrest specific 2. (61 aa)
STK24Serine/threonine kinase 24. (443 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (324 aa)
ENSGGOP00000046010Protein kinase domain-containing protein. (372 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (388 aa)
DSPDesmoplakin. (2868 aa)
ENSGGOP00000038483Protein kinase domain-containing protein. (392 aa)
ENSGGOP00000036167SH3 domain containing GRB2 like, endophilin B1. (402 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (999 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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