STRINGSTRING
ENSGGOP00000049412 ENSGGOP00000049412 CASP7 CASP7 ENSGGOP00000041462 ENSGGOP00000041462 MAPK1 MAPK1 APAF1 APAF1 GSDMB GSDMB ENSGGOP00000031996 ENSGGOP00000031996 ENSGGOP00000031130 ENSGGOP00000031130 CYCS CYCS G3SDM2_GORGO G3SDM2_GORGO G3SAG0_GORGO G3SAG0_GORGO G3S8N2_GORGO G3S8N2_GORGO SEPTIN5 SEPTIN5 MAPK3 MAPK3 CASP3 CASP3 G3S0J3_GORGO G3S0J3_GORGO APIP APIP BAK1 BAK1 G3RQE7_GORGO G3RQE7_GORGO G3RLK9_GORGO G3RLK9_GORGO SEPTIN1 SEPTIN1 UACA UACA NPVF NPVF BAX BAX AVEN AVEN XIAP XIAP SEPTIN4 SEPTIN4 BIRC8 BIRC8 G3QV30_GORGO G3QV30_GORGO DIABLO DIABLO GSDME GSDME TMEM198 TMEM198 C1QBP C1QBP CASP9 CASP9 CARD8 CARD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000049412Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (117 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (388 aa)
ENSGGOP00000041462Uncharacterized protein. (164 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
GSDMBGasdermin B. (416 aa)
ENSGGOP00000031996Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (91 aa)
ENSGGOP00000031130Uncharacterized protein. (189 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
G3SDM2_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
G3SAG0_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
G3S8N2_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (91 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
G3S0J3_GORGODUF4203 domain-containing protein. (106 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
G3RQE7_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
G3RLK9_GORGOCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1403 aa)
NPVFNeuropeptide VF precursor. (196 aa)
BAXBCL2 associated X, apoptosis regulator. (217 aa)
AVENApoptosis and caspase activation inhibitor. (358 aa)
XIAPUncharacterized protein. (371 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1012 aa)
BIRC8Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (236 aa)
G3QV30_GORGOGasdermin D. (532 aa)
DIABLOUncharacterized protein. (166 aa)
GSDMEGasdermin E. (496 aa)
TMEM198Transmembrane protein 198. (360 aa)
C1QBPComplement C1q binding protein. (281 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
CARD8Caspase recruitment domain family member 8. (522 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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