STRINGSTRING
ENSGGOP00000045589 ENSGGOP00000045589 NCBP1 NCBP1 NELFB NELFB ELOC ELOC SUPT16H SUPT16H ELL ELL G3QK95_GORGO G3QK95_GORGO G3QMV9_GORGO G3QMV9_GORGO EAF1 EAF1 POLR2D POLR2D POLR2F POLR2F GTF2F2 GTF2F2 G3QV73_GORGO G3QV73_GORGO SUPT4H1 SUPT4H1 MNAT1 MNAT1 GTF2H3 GTF2H3 G3R2E6_GORGO G3R2E6_GORGO IWS1 IWS1 POLR2L POLR2L MLLT1 MLLT1 CDK9 CDK9 CTDP1 CTDP1 G3R6M6_GORGO G3R6M6_GORGO CTR9 CTR9 WDR61 WDR61 POLR2G POLR2G AFF4 AFF4 SSRP1 SSRP1 G3RBC2_GORGO G3RBC2_GORGO CDK7 CDK7 RTF1 RTF1 NELFA NELFA GTF2H4 GTF2H4 SUPT5H SUPT5H NCBP2L NCBP2L POLR2A POLR2A ELOA ELOA ERCC3 ERCC3 ELOB ELOB POLR2I POLR2I SUPT6H SUPT6H AFF1 AFF1 GTF2H1 GTF2H1 POLR2K POLR2K GTF2H5 GTF2H5 POLR2C POLR2C G3RUE6_GORGO G3RUE6_GORGO G3RUP8_GORGO G3RUP8_GORGO NELFE NELFE POLR2J POLR2J G3RWF8_GORGO G3RWF8_GORGO G3RZJ6_GORGO G3RZJ6_GORGO TCEA1 TCEA1 G3SGP8_GORGO G3SGP8_GORGO ENSGGOP00000029268 ENSGGOP00000029268 ENSGGOP00000030375 ENSGGOP00000030375 ENSGGOP00000031416 ENSGGOP00000031416 CDC73 CDC73 CCNT2 CCNT2 ENSGGOP00000032824 ENSGGOP00000032824 ENSGGOP00000033590 ENSGGOP00000033590 EAF2 EAF2 ENSGGOP00000033816 ENSGGOP00000033816 ENSGGOP00000033975 ENSGGOP00000033975 ENSGGOP00000034792 ENSGGOP00000034792 ENSGGOP00000036704 ENSGGOP00000036704 ENSGGOP00000037296 ENSGGOP00000037296 NCBP2 NCBP2 PAF1 PAF1 ENSGGOP00000042610 ENSGGOP00000042610 ENSGGOP00000045306 ENSGGOP00000045306 NELFCD NELFCD GTF2F1 GTF2F1 CCNH CCNH POLR2B POLR2B ENSGGOP00000049327 ENSGGOP00000049327 ENSGGOP00000050004 ENSGGOP00000050004 ERCC2 ERCC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000045589Ubiquitin-like domain-containing protein. (57 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
NELFBNegative elongation factor complex member B. (628 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
ELLUncharacterized protein. (488 aa)
G3QK95_GORGODNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (125 aa)
G3QMV9_GORGORNA_pol_L_2 domain-containing protein. (124 aa)
EAF1ELL associated factor 1. (268 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
G3QV73_GORGOTFIIS N-terminal domain-containing protein. (537 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
G3R2E6_GORGOSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (819 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
MLLT1MLLT1 super elongation complex subunit. (556 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
G3R6M6_GORGORNA polymerase II subunit E. (210 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
WDR61WD repeat domain 61. (305 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
G3RBC2_GORGOCyclin T1; Belongs to the cyclin family. (611 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa)
NELFANegative elongation factor complex member A. (528 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
SUPT5HTranscription elongation factor SPT5. (1140 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
ELOAElongin A. (798 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
ELOBElongin B. (161 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
AFF1AF4/FMR2 family member 1. (1219 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
G3RUE6_GORGOUncharacterized protein. (104 aa)
G3RUP8_GORGOTFIIS N-terminal domain-containing protein. (552 aa)
NELFENegative elongation factor complex member E. (381 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (125 aa)
G3RWF8_GORGOMLLT3 super elongation complex subunit. (569 aa)
G3RZJ6_GORGOLEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
TCEA1Transcription elongation factor A1. (301 aa)
G3SGP8_GORGOSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSGGOP00000029268Uncharacterized protein. (93 aa)
ENSGGOP00000030375RNA_pol_L_2 domain-containing protein. (130 aa)
ENSGGOP00000031416TFIIS N-terminal domain-containing protein. (545 aa)
CDC73Cell division cycle 73. (452 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
ENSGGOP00000032824Spt4 domain-containing protein. (59 aa)
ENSGGOP00000033590Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (103 aa)
EAF2ELL associated factor 2. (266 aa)
ENSGGOP00000033816RNA_pol_L_2 domain-containing protein. (173 aa)
ENSGGOP00000033975Uncharacterized protein. (851 aa)
ENSGGOP00000034792Uncharacterized protein. (55 aa)
ENSGGOP00000036704Uncharacterized protein. (58 aa)
ENSGGOP00000037296TFIIF_beta domain-containing protein. (102 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (533 aa)
ENSGGOP00000042610Protein kinase domain-containing protein. (322 aa)
ENSGGOP00000045306Uncharacterized protein. (101 aa)
NELFCDNegative elongation factor complex member C/D. (604 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
ENSGGOP00000049327TFIIS N-terminal domain-containing protein. (545 aa)
ENSGGOP00000050004Uncharacterized protein; Belongs to the cyclin family. (407 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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