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G3QK95_GORGO G3QK95_GORGO G3QMV9_GORGO G3QMV9_GORGO GTF2H5 GTF2H5 POLR2K POLR2K GTF2H1 GTF2H1 POLR2I POLR2I ERCC3 ERCC3 POLR2A POLR2A NCBP2L NCBP2L C6H6orf15 C6H6orf15 SUPT5H SUPT5H GTF2H4 GTF2H4 NELFA NELFA CDK7 CDK7 POLR2G POLR2G G3R6M6_GORGO G3R6M6_GORGO CTDP1 CTDP1 POLR2L POLR2L GTF2H3 GTF2H3 MNAT1 MNAT1 SUPT4H1 SUPT4H1 GTF2F2 GTF2F2 POLR2F POLR2F POLR2D POLR2D NCBP1 NCBP1 ERCC2 ERCC2 POLR2B POLR2B CCNH CCNH GTF2F1 GTF2F1 NELFCD NELFCD ENSGGOP00000042610 ENSGGOP00000042610 NCBP2 NCBP2 ENSGGOP00000037296 ENSGGOP00000037296 ENSGGOP00000036704 ENSGGOP00000036704 ENSGGOP00000034792 ENSGGOP00000034792 ENSGGOP00000033816 ENSGGOP00000033816 ENSGGOP00000032824 ENSGGOP00000032824 ENSGGOP00000030375 ENSGGOP00000030375 ENSGGOP00000029268 ENSGGOP00000029268 G3SEL2_GORGO G3SEL2_GORGO POLR2J POLR2J NELFE NELFE POLR2C POLR2C NELFB NELFB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3QK95_GORGODNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (125 aa)
G3QMV9_GORGORNA_pol_L_2 domain-containing protein. (124 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
C6H6orf15Chromosome 6 open reading frame 15. (325 aa)
SUPT5HTranscription elongation factor SPT5. (1140 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
NELFANegative elongation factor complex member A. (528 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
G3R6M6_GORGORNA polymerase II subunit E. (210 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (810 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
NELFCDNegative elongation factor complex member C/D. (604 aa)
ENSGGOP00000042610Protein kinase domain-containing protein. (322 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
ENSGGOP00000037296TFIIF_beta domain-containing protein. (102 aa)
ENSGGOP00000036704Uncharacterized protein. (58 aa)
ENSGGOP00000034792Uncharacterized protein. (55 aa)
ENSGGOP00000033816RNA_pol_L_2 domain-containing protein. (173 aa)
ENSGGOP00000032824Spt4 domain-containing protein. (59 aa)
ENSGGOP00000030375RNA_pol_L_2 domain-containing protein. (130 aa)
ENSGGOP00000029268Uncharacterized protein. (93 aa)
G3SEL2_GORGOUncharacterized protein. (263 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (125 aa)
NELFENegative elongation factor complex member E. (381 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
NELFBNegative elongation factor complex member B. (628 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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