STRINGSTRING
ENSGGOP00000031121 ENSGGOP00000031121 CARD16 CARD16 CASP9 CASP9 G3QHL6_GORGO G3QHL6_GORGO UBC UBC BCL2 BCL2 NLRP14 NLRP14 MAP3K7 MAP3K7 BCL2L1 BCL2L1 NOD1 NOD1 MAPK11 MAPK11 BIRC2 BIRC2 TAB1 TAB1 NLRP2 NLRP2 TXNDC2 TXNDC2 RPS27A RPS27A NME8 NME8 ITCH ITCH NFKB2 NFKB2 TXN TXN AAMP AAMP G3QV95_GORGO G3QV95_GORGO IKBKB IKBKB AIM2 AIM2 TRAF6 TRAF6 BIRC3 BIRC3 ARRDC2 ARRDC2 G3QSG6_GORGO G3QSG6_GORGO PANX-2 PANX-2 G3QRP1_GORGO G3QRP1_GORGO IKBKG IKBKG NLRP3 NLRP3 UBA52 UBA52 ARRDC3 ARRDC3 MAPK13 MAPK13 CASP2 CASP2 TNFAIP3 TNFAIP3 NLRC4 NLRC4 RNH1 RNH1 MAP2K6 MAP2K6 G3S9Y6_GORGO G3S9Y6_GORGO TXNDC8 TXNDC8 G3SEP4_GORGO G3SEP4_GORGO ARRDC5 ARRDC5 RELA RELA ENSGGOP00000029367 ENSGGOP00000029367 ENSGGOP00000031959 ENSGGOP00000031959 ENSGGOP00000032091 ENSGGOP00000032091 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000033404 ENSGGOP00000033404 UBE2N UBE2N ENSGGOP00000035952 ENSGGOP00000035952 ENSGGOP00000036074 ENSGGOP00000036074 ENSGGOP00000038520 ENSGGOP00000038520 NME9 NME9 NAIP NAIP ENSGGOP00000045267 ENSGGOP00000045267 PYDC2 PYDC2 HMOX1 HMOX1 ENSGGOP00000046758 ENSGGOP00000046758 ENSGGOP00000047060 ENSGGOP00000047060 ENSGGOP00000047423 ENSGGOP00000047423 ENSGGOP00000047842 ENSGGOP00000047842 ENSGGOP00000048129 ENSGGOP00000048129 ENSGGOP00000049072 ENSGGOP00000049072 PSTPIP2 PSTPIP2 APP APP CYLD CYLD ARRDC4 ARRDC4 HSP90AB1 HSP90AB1 CHUK CHUK NLRP10 NLRP10 NLRP7 NLRP7 NOD2 NOD2 RIPK2 RIPK2 NLRP1 NLRP1 TXNIP TXNIP G3R8J0_GORGO G3R8J0_GORGO G3R8R1_GORGO G3R8R1_GORGO G3R9C2_GORGO G3R9C2_GORGO G3RD86_GORGO G3RD86_GORGO MAPK12 MAPK12 G3RI71_GORGO G3RI71_GORGO MEFV MEFV TAB2 TAB2 PYCARD PYCARD IRAK1 IRAK1 NFKB1 NFKB1 TAB3 TAB3 ENSGGOP00000019740 ENSGGOP00000019740 BIRC7 BIRC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000031121Uncharacterized protein. (361 aa)
CARD16Caspase recruitment domain family member 16. (197 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
G3QHL6_GORGOInterleukin 1 receptor associated kinase 2. (538 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
NLRP14NLR family pyrin domain containing 14. (1093 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
BCL2L1BCL2 like 1. (233 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
NLRP2NLR family pyrin domain containing 2. (1040 aa)
TXNDC2Thioredoxin domain-containing protein. (358 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
NME8NME/NM23 family member 8. (588 aa)
ITCHE3 ubiquitin-protein ligase. (903 aa)
NFKB2Nuclear factor kappa B subunit 2. (902 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
AAMPAngio associated migratory cell protein. (434 aa)
G3QV95_GORGOSGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (365 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
AIM2Absent in melanoma 2. (343 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
ARRDC2Arrestin domain containing 2. (407 aa)
G3QSG6_GORGOMitogen-activated protein kinase kinase kinase 20. (780 aa)
PANX-2Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
NLRP3NLR family pyrin domain containing 3. (1028 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
ARRDC3Arrestin domain containing 3. (414 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
RNH1Uncharacterized protein. (461 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
G3S9Y6_GORGOThioredoxin domain-containing protein. (93 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
ARRDC5Arrestin domain containing 5. (342 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ENSGGOP00000029367Pyrin domain-containing protein. (110 aa)
ENSGGOP00000031959Thioredoxin domain-containing protein. (106 aa)
ENSGGOP00000032091Caspase 4; Belongs to the peptidase C14A family. (377 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000033404Caspase 8; Belongs to the peptidase C14A family. (496 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
ENSGGOP00000036074HATPase_c domain-containing protein. (596 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
NAIPUncharacterized protein. (198 aa)
ENSGGOP00000045267Uncharacterized protein; Belongs to the peptidase C14A family. (342 aa)
PYDC2Pyrin domain-containing protein. (97 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (289 aa)
ENSGGOP00000046758Caspase 1; Belongs to the peptidase C14A family. (404 aa)
ENSGGOP00000047060UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
ENSGGOP00000047423UBIQUITIN_CONJUGAT_2 domain-containing protein. (126 aa)
ENSGGOP00000047842Uncharacterized protein. (469 aa)
ENSGGOP00000048129Caspase recruitment domain family member 9. (536 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
PSTPIP2Proline-serine-threonine phosphatase interacting protein 2. (334 aa)
APPAmyloid beta precursor protein. (771 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ARRDC4Arrestin domain containing 4. (353 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
CHUKIKKbetaNEMObind domain-containing protein. (434 aa)
NLRP10NLR family pyrin domain containing 10. (661 aa)
NLRP7NLR family pyrin domain containing 7. (1037 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NLRP1NLR family pyrin domain containing 1. (1471 aa)
TXNIPThioredoxin interacting protein. (391 aa)
G3R8J0_GORGOArrestin domain containing 1. (438 aa)
G3R8R1_GORGOCaspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (341 aa)
G3R9C2_GORGOProline-serine-threonine phosphatase interacting protein 1. (418 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
MAPK12Mitogen-activated protein kinase. (312 aa)
G3RI71_GORGONACHT domain-containing protein. (1127 aa)
MEFVMEFV innate immuity regulator, pyrin. (781 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
PYCARDPYD and CARD domain containing. (195 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
ENSGGOP00000019740annotation not available (156 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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