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PPP2CA | Serine/threonine-protein phosphatase. (309 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
NAB2 | NGFI-A binding protein 2. (525 aa) | ||||
SGK1 | Non-specific serine/threonine protein kinase. (526 aa) | ||||
RALB | RAS like proto-oncogene B. (228 aa) | ||||
REST | RE1 silencing transcription factor. (1081 aa) | ||||
EGR3 | Early growth response 3. (349 aa) | ||||
G3QK90_GORGO | Uncharacterized protein. (206 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
G3QKL3_GORGO | Uncharacterized protein. (188 aa) | ||||
RALGDS | Uncharacterized protein. (914 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
ARC | Activity regulated cytoskeleton associated protein. (396 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
G3QRE4_GORGO | Tribbles pseudokinase 1. (372 aa) | ||||
ASCL1 | Achaete-scute family bHLH transcription factor 1. (234 aa) | ||||
RIT2 | Ras like without CAAX 2. (217 aa) | ||||
DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (937 aa) | ||||
PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (304 aa) | ||||
EGR4 | Early growth response 4. (589 aa) | ||||
PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) | ||||
ASCL2 | Achaete-scute family bHLH transcription factor 2. (193 aa) | ||||
CDK5R2 | Uncharacterized protein. (95 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
MAPK15 | Mitogen-activated protein kinase. (544 aa) | ||||
CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa) | ||||
G3QYD4_GORGO | KRAS proto-oncogene, GTPase. (189 aa) | ||||
TCF12 | Transcription factor 12. (706 aa) | ||||
EP300 | E1A binding protein p300. (2416 aa) | ||||
ID3 | Inhibitor of DNA binding 3, HLH protein. (119 aa) | ||||
G3R009_GORGO | NTPase KAP family P-loop domain containing 1. (610 aa) | ||||
DNM3 | Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa) | ||||
ELK1 | ETS transcription factor ELK1. (452 aa) | ||||
G3R0F2_GORGO | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
G3R428_GORGO | Protein phosphatase 2 scaffold subunit Abeta. (620 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) | ||||
SHC3 | SHC adaptor protein 3. (598 aa) | ||||
ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) | ||||
RHOA | Uncharacterized protein. (179 aa) | ||||
G3RBH6_GORGO | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (227 aa) | ||||
SHC1 | SHC adaptor protein 1. (584 aa) | ||||
DNAL4 | Dynein light chain. (105 aa) | ||||
NAB1 | NGFI-A binding protein 1. (471 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (767 aa) | ||||
FNBP4 | Formin binding protein 4. (1019 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (312 aa) | ||||
MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) | ||||
RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) | ||||
IRS2 | Insulin receptor substrate 2. (1220 aa) | ||||
G3RHM6_GORGO | WRNPLPNID domain-containing protein. (946 aa) | ||||
G3RIH3_GORGO | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) | ||||
ID1 | Inhibitor of DNA binding 1, HLH protein. (155 aa) | ||||
DNM1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (319 aa) | ||||
TPH1 | Tryptophan hydroxylase 1. (444 aa) | ||||
G3RMT0_GORGO | SH3 domain containing GRB2 like 3, endophilin A3. (317 aa) | ||||
G3RNM7_GORGO | Protein kinase domain-containing protein. (405 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
CHD4 | Uncharacterized protein. (1912 aa) | ||||
G3RSU6_GORGO | Uncharacterized protein. (499 aa) | ||||
G3RTG9_GORGO | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (880 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (781 aa) | ||||
FOSB | FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa) | ||||
G3S176_GORGO | MADS-box domain-containing protein. (473 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (322 aa) | ||||
RIT1 | Ras like without CAAX 1. (236 aa) | ||||
AP2B1 | AP complex subunit beta. (951 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (325 aa) | ||||
DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) | ||||
G3S843_GORGO | BZIP domain-containing protein. (215 aa) | ||||
LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (768 aa) | ||||
VRK3 | VRK serine/threonine kinase 3. (474 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
MEF2A | Myocyte enhancer factor 2A. (504 aa) | ||||
G3SGM2_GORGO | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
MEF2D | Myocyte enhancer factor 2D. (521 aa) | ||||
VGF | Uncharacterized protein. (336 aa) | ||||
DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (349 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (522 aa) | ||||
SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (352 aa) | ||||
ENSGGOP00000030268 | Uncharacterized protein. (596 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
ENSGGOP00000031261 | Myocyte enhancer factor 2C. (483 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
ENSGGOP00000031915 | Uncharacterized protein. (110 aa) | ||||
ENSGGOP00000032619 | cAMP responsive element binding protein 1. (341 aa) | ||||
ENSGGOP00000032627 | Uncharacterized protein. (118 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
ENSGGOP00000033662 | Dynamin_M domain-containing protein. (120 aa) | ||||
CREM | cAMP responsive element modulator. (344 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) | ||||
RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) | ||||
ENSGGOP00000035103 | Protein kinase domain-containing protein. (379 aa) | ||||
ENSGGOP00000037735 | Uncharacterized protein. (471 aa) | ||||
ENSGGOP00000037801 | Uncharacterized protein. (203 aa) | ||||
CRKL | Uncharacterized protein. (201 aa) | ||||
MAPKAPK2 | Protein kinase domain-containing protein. (374 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (128 aa) | ||||
ENSGGOP00000041959 | Uncharacterized protein. (413 aa) | ||||
PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (849 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
ENSGGOP00000043662 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) | ||||
ENSGGOP00000044220 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (88 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) | ||||
ATF1 | Activating transcription factor 1. (270 aa) | ||||
ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1773 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (300 aa) | ||||
RALA | Uncharacterized protein. (112 aa) | ||||
ENSGGOP00000048050 | SH2 domain-containing protein. (132 aa) | ||||
ENSGGOP00000048177 | B2-adapt-app_C domain-containing protein. (874 aa) | ||||
ENSGGOP00000048306 | Adaptin_N domain-containing protein. (344 aa) | ||||
ENSGGOP00000048385 | Rap guanine nucleotide exchange factor 1. (1095 aa) | ||||
ENSGGOP00000049072 | Protein kinase domain-containing protein. (296 aa) | ||||
SHC2 | Uncharacterized protein. (518 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (943 aa) |