STRINGSTRING
NOTCH2 NOTCH2 MAML2 MAML2 NEURL1 NEURL1 MDK MDK MAML1 MAML1 JAG1 JAG1 ENSGGOP00000019740 ENSGGOP00000019740 APH1A APH1A PSENEN PSENEN MAMLD1 MAMLD1 HES4 HES4 G3RB29_GORGO G3RB29_GORGO MIB1 MIB1 G3R524_GORGO G3R524_GORGO G3R439_GORGO G3R439_GORGO HES1 HES1 EP300 EP300 RPS27A RPS27A G3QXA1_GORGO G3QXA1_GORGO FCER2 FCER2 DLL1 DLL1 G3QQC0_GORGO G3QQC0_GORGO G3SEP4_GORGO G3SEP4_GORGO PSEN2 PSEN2 PSEN1 PSEN1 ENSGGOP00000049329 ENSGGOP00000049329 NCSTN NCSTN ENSGGOP00000045153 ENSGGOP00000045153 APH1B APH1B RBPJ RBPJ ENSGGOP00000038520 ENSGGOP00000038520 ENSGGOP00000032619 ENSGGOP00000032619 CNTN1 CNTN1 DLL4 DLL4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH2Notch receptor 2. (2373 aa)
MAML2Mastermind like transcriptional coactivator 2. (1155 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
MDKMidkine. (143 aa)
MAML1Mastermind like transcriptional coactivator 1. (939 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ENSGGOP00000019740annotation not available (156 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
MAMLD1Mastermind like domain containing 1. (999 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
G3RB29_GORGOGranzyme B; Belongs to the peptidase S1 family. (247 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
G3R524_GORGOADAM metallopeptidase domain 10. (705 aa)
G3R439_GORGOHes family bHLH transcription factor 5. (165 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
EP300E1A binding protein p300. (2416 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
G3QXA1_GORGODelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1199 aa)
FCER2Fc fragment of IgE receptor II. (321 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
G3QQC0_GORGOUncharacterized protein. (315 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
ENSGGOP00000049329Uncharacterized protein. (425 aa)
NCSTNNicastrin. (721 aa)
ENSGGOP00000045153Mindbomb E3 ubiquitin protein ligase 2. (979 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (488 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
ENSGGOP00000032619cAMP responsive element binding protein 1. (341 aa)
CNTN1Contactin 1. (1028 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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