STRINGSTRING
CNTN1 CNTN1 DLK1 DLK1 UBC UBC PSEN1 PSEN1 PSEN2 PSEN2 UBA52 UBA52 G3QQC0_GORGO G3QQC0_GORGO G3QRS9_GORGO G3QRS9_GORGO ARRB2 ARRB2 DLL1 DLL1 ITCH ITCH G3QXA1_GORGO G3QXA1_GORGO RPS27A RPS27A ARRB1 ARRB1 NOTCH1 NOTCH1 G3R4C9_GORGO G3R4C9_GORGO G3R524_GORGO G3R524_GORGO MIB1 MIB1 ADAM17 ADAM17 DNER DNER PSENEN PSENEN APH1A APH1A DTX4 DTX4 ENSGGOP00000019740 ENSGGOP00000019740 JAG1 JAG1 NEURL1 NEURL1 G3SEP4_GORGO G3SEP4_GORGO DLL4 DLL4 NUMB NUMB ENSGGOP00000038520 ENSGGOP00000038520 APH1B APH1B ENSGGOP00000045153 ENSGGOP00000045153 NCSTN NCSTN ENSGGOP00000050590 ENSGGOP00000050590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNTN1Contactin 1. (1028 aa)
DLK1Delta like non-canonical Notch ligand 1. (383 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
G3QQC0_GORGOUncharacterized protein. (315 aa)
G3QRS9_GORGODeltex E3 ubiquitin ligase 2. (514 aa)
ARRB2Arrestin beta 2. (409 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ITCHE3 ubiquitin-protein ligase. (903 aa)
G3QXA1_GORGODelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1199 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ARRB1Arrestin beta 1. (418 aa)
NOTCH1Uncharacterized protein. (1606 aa)
G3R4C9_GORGODeltex E3 ubiquitin ligase 1. (540 aa)
G3R524_GORGOADAM metallopeptidase domain 10. (705 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
DNERDelta/notch like EGF repeat containing. (736 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
ENSGGOP00000019740annotation not available (156 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
NUMBNUMB endocytic adaptor protein. (651 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ENSGGOP00000045153Mindbomb E3 ubiquitin protein ligase 2. (979 aa)
NCSTNNicastrin. (721 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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