STRINGSTRING
WWTR1 WWTR1 G3QFK3_GORGO G3QFK3_GORGO UBC UBC MEN1 MEN1 USP9X USP9X UBA52 UBA52 SMAD2 SMAD2 YBX1 YBX1 TFDP1 TFDP1 RBL1 RBL1 COL1A2 COL1A2 CDK8 CDK8 SMURF2 SMURF2 SERPINE1 SERPINE1 G3QWJ5_GORGO G3QWJ5_GORGO CCNC CCNC RPS27A RPS27A FURIN FURIN EP300 EP300 E2F5 E2F5 G3R4L4_GORGO G3R4L4_GORGO SMAD7 SMAD7 CDK9 CDK9 HDAC1 HDAC1 TGIF2 TGIF2 E2F4 E2F4 G3RA25_GORGO G3RA25_GORGO G3RBC2_GORGO G3RBC2_GORGO SMAD4 SMAD4 G3RDV6_GORGO G3RDV6_GORGO IRX2 IRX2 MKX MKX TRIM33 TRIM33 RNF111 RNF111 IRX1 IRX1 MYC MYC G3RT71_GORGO G3RT71_GORGO ATP1B4 ATP1B4 ENSGGOP00000019740 ENSGGOP00000019740 G3RXJ7_GORGO G3RXJ7_GORGO SKIL SKIL MAPK3 MAPK3 IRX5 IRX5 G3S2R7_GORGO G3S2R7_GORGO SNW1 SNW1 G3S8E4_GORGO G3S8E4_GORGO TFDP3 TFDP3 IRX6 IRX6 PARP1 PARP1 G3SEP4_GORGO G3SEP4_GORGO G3SF24_GORGO G3SF24_GORGO STAT1 STAT1 PPM1A PPM1A ENSGGOP00000028212 ENSGGOP00000028212 ENSGGOP00000031603 ENSGGOP00000031603 CCNT2 CCNT2 TGIF1 TGIF1 NEDD4L NEDD4L ENSGGOP00000034117 ENSGGOP00000034117 ENSGGOP00000034513 ENSGGOP00000034513 ENSGGOP00000035311 ENSGGOP00000035311 ENSGGOP00000035399 ENSGGOP00000035399 ENSGGOP00000036046 ENSGGOP00000036046 UBE2D1 UBE2D1 ENSGGOP00000037295 ENSGGOP00000037295 ENSGGOP00000038520 ENSGGOP00000038520 ENSGGOP00000038823 ENSGGOP00000038823 CDKN2B CDKN2B MAPK1 MAPK1 ENSGGOP00000043083 ENSGGOP00000043083 SMAD3 SMAD3 JUNB JUNB ENSGGOP00000050004 ENSGGOP00000050004 ENSGGOP00000050067 ENSGGOP00000050067 TFDP2 TFDP2 ENSGGOP00000050590 ENSGGOP00000050590 IRX4 IRX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WWTR1WW domain containing transcription regulator 1. (400 aa)
G3QFK3_GORGOMeis_PKNOX_N domain-containing protein. (374 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
MEN1Menin 1. (615 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2591 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
YBX1Y-box binding protein 1. (324 aa)
TFDP1Transcription factor. (411 aa)
RBL1RB transcriptional corepressor like 1. (1066 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
SMURF2E3 ubiquitin-protein ligase. (750 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
G3QWJ5_GORGOP/Homo B domain-containing protein. (687 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
EP300E1A binding protein p300. (2416 aa)
E2F5E2F transcription factor 5. (346 aa)
G3R4L4_GORGOSKI proto-oncogene. (700 aa)
SMAD7MH2 domain-containing protein. (211 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
E2F4E2F transcription factor 4. (419 aa)
G3RA25_GORGOSp1 transcription factor. (786 aa)
G3RBC2_GORGOCyclin T1; Belongs to the cyclin family. (611 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
G3RDV6_GORGOIroquois homeobox 3. (501 aa)
IRX2Iroquois homeobox 2. (388 aa)
MKXMohawk homeobox. (352 aa)
TRIM33Tripartite motif containing 33. (1040 aa)
RNF111Ring finger protein 111. (1003 aa)
IRX1Homeobox domain-containing protein. (480 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
G3RT71_GORGOCSD_1 domain-containing protein. (318 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ENSGGOP00000019740annotation not available (156 aa)
G3RXJ7_GORGOCYCLIN domain-containing protein; Belongs to the cyclin family. (190 aa)
SKILSKI like proto-oncogene. (684 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
IRX5Iroquois homeobox 5. (483 aa)
G3S2R7_GORGOCSP domain-containing protein. (280 aa)
SNW1SNW domain containing 1. (571 aa)
G3S8E4_GORGOCSP domain-containing protein. (314 aa)
TFDP3Transcription factor. (405 aa)
IRX6Iroquois homeobox 6. (446 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
G3SF24_GORGOHomeobox domain-containing protein. (255 aa)
STAT1Signal transducer and activator of transcription. (777 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
ENSGGOP00000028212annotation not available (480 aa)
ENSGGOP00000031603Homeobox domain-containing protein. (333 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
TGIF1TGFB induced factor homeobox 1. (399 aa)
NEDD4LUncharacterized protein. (1178 aa)
ENSGGOP00000034117Uncharacterized protein. (90 aa)
ENSGGOP00000034513Ubiquitin-like domain-containing protein. (156 aa)
ENSGGOP00000035311Uncharacterized protein. (52 aa)
ENSGGOP00000035399annotation not available (90 aa)
ENSGGOP00000036046CYCLIN domain-containing protein; Belongs to the cyclin family. (241 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSGGOP00000037295CYCLIN domain-containing protein; Belongs to the cyclin family. (226 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
ENSGGOP00000038823Nuclear receptor corepressor 1. (2386 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSGGOP00000043083Nuclear receptor corepressor 2. (2519 aa)
SMAD3Mothers against decapentaplegic homolog. (356 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ENSGGOP00000050004Uncharacterized protein; Belongs to the cyclin family. (407 aa)
ENSGGOP00000050067Transcription factor. (370 aa)
TFDP2Transcription factor. (447 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
IRX4Uncharacterized protein. (196 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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