35 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TGIF1	TGFB induced factor homeobox 1. (399 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	UBC	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
	USP9X	Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2591 aa)
	UBA52	Ubiquitin-like domain-containing protein. (233 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	SMURF2	E3 ubiquitin-protein ligase. (750 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	G3R4L4_GORGO	SKI proto-oncogene. (700 aa)
	SMAD7	MH2 domain-containing protein. (211 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	TRIM33	Tripartite motif containing 33. (1040 aa)
	RNF111	Ring finger protein 111. (1003 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
	ENSGGOP00000019740	annotation not available (156 aa)
	SKIL	SKI like proto-oncogene. (684 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	SNW1	SNW domain containing 1. (571 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	G3SEP4_GORGO	Ubiquitin-like domain-containing protein. (156 aa)
	G3SF24_GORGO	Homeobox domain-containing protein. (255 aa)
	STAT1	Signal transducer and activator of transcription. (777 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	NEDD4L	Uncharacterized protein. (1178 aa)
	ENSGGOP00000034117	Uncharacterized protein. (90 aa)
	ENSGGOP00000035399	annotation not available (90 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	ENSGGOP00000038520	Ubiquitin-like domain-containing protein. (187 aa)
	ENSGGOP00000038823	Nuclear receptor corepressor 1. (2386 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	ENSGGOP00000043083	Nuclear receptor corepressor 2. (2519 aa)
	SMAD3	Mothers against decapentaplegic homolog. (356 aa)
	ENSGGOP00000050590	Uncharacterized protein. (258 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	MAPK1	ENSGGOP00000019121	ENSGGOP00000040522	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	MAPK3	ENSGGOP00000019121	ENSGGOP00000021887	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase.	0.900
ATP1B4	SMAD7	ENSGGOP00000019121	ENSGGOP00000010290	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	MH2 domain-containing protein.	0.613
ATP1B4	SNW1	ENSGGOP00000019121	ENSGGOP00000022780	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.892
ENSGGOP00000019740	ENSGGOP00000038520	ENSGGOP00000019740	ENSGGOP00000038520	annotation not available	Ubiquitin-like domain-containing protein.	0.544
ENSGGOP00000019740	ENSGGOP00000050590	ENSGGOP00000019740	ENSGGOP00000050590	annotation not available	Uncharacterized protein.	0.687
ENSGGOP00000019740	G3R4L4_GORGO	ENSGGOP00000019740	ENSGGOP00000010220	annotation not available	SKI proto-oncogene.	0.419
ENSGGOP00000019740	G3SEP4_GORGO	ENSGGOP00000019740	ENSGGOP00000026578	annotation not available	Ubiquitin-like domain-containing protein.	0.543
ENSGGOP00000019740	NEDD4L	ENSGGOP00000019740	ENSGGOP00000032868	annotation not available	Uncharacterized protein.	0.626
ENSGGOP00000019740	PARP1	ENSGGOP00000019740	ENSGGOP00000025582	annotation not available	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.432
ENSGGOP00000019740	RNF111	ENSGGOP00000019740	ENSGGOP00000016594	annotation not available	Ring finger protein 111.	0.552
ENSGGOP00000019740	RPS27A	ENSGGOP00000019740	ENSGGOP00000007509	annotation not available	Ubiquitin-like domain-containing protein.	0.543
ENSGGOP00000019740	SKIL	ENSGGOP00000019740	ENSGGOP00000020819	annotation not available	SKI like proto-oncogene.	0.413
ENSGGOP00000019740	SMAD4	ENSGGOP00000019740	ENSGGOP00000013332	annotation not available	Mothers against decapentaplegic homolog.	0.424
ENSGGOP00000019740	SMURF2	ENSGGOP00000019740	ENSGGOP00000006862	annotation not available	E3 ubiquitin-protein ligase.	0.710
ENSGGOP00000019740	TRIM33	ENSGGOP00000019740	ENSGGOP00000016037	annotation not available	Tripartite motif containing 33.	0.417
ENSGGOP00000019740	UBA52	ENSGGOP00000019740	ENSGGOP00000004534	annotation not available	Ubiquitin-like domain-containing protein.	0.959
ENSGGOP00000019740	UBC	ENSGGOP00000019740	ENSGGOP00000001286	annotation not available	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.905
ENSGGOP00000019740	UBE2D1	ENSGGOP00000019740	ENSGGOP00000036276	annotation not available	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.660
ENSGGOP00000034117	ENSGGOP00000050590	ENSGGOP00000034117	ENSGGOP00000050590	Uncharacterized protein.	Uncharacterized protein.	0.437