STRINGSTRING
ENSGGOP00000035777 ENSGGOP00000035777 DYNC1H1 DYNC1H1 DYNC1I1 DYNC1I1 PPP2CA PPP2CA PPP2R5B PPP2R5B KIF18A KIF18A NUP160 NUP160 NDC80 NDC80 CNTD2 CNTD2 CENPT CENPT CCNB1 CCNB1 CENPH CENPH G3QI01_GORGO G3QI01_GORGO BUB1B BUB1B G3QIQ6_GORGO G3QIQ6_GORGO CENPF CENPF MAD2L1 MAD2L1 ERCC6L2 ERCC6L2 G3QK51_GORGO G3QK51_GORGO AURKB AURKB TUBB6 TUBB6 NSL1 NSL1 ZWILCH ZWILCH STAG2 STAG2 NUP37 NUP37 ITGB3BP ITGB3BP TUBE1 TUBE1 PDS5B PDS5B TUBB4B TUBB4B CENPK CENPK DYNC1LI2 DYNC1LI2 PAFAH1B1 PAFAH1B1 SGO1 SGO1 NUP85 NUP85 PPP2R1A PPP2R1A KIF2B KIF2B TAOK1 TAOK1 ZWINT ZWINT PPP2R5D PPP2R5D NUP43 NUP43 PDS5A PDS5A CCNB2 CCNB2 CDCA8 CDCA8 NUF2 NUF2 AURKC AURKC G3QYL5_GORGO G3QYL5_GORGO SPC24 SPC24 CCNB3 CCNB3 CENPC CENPC SEC13 SEC13 G3R428_GORGO G3R428_GORGO CDC20 CDC20 MIS12 MIS12 TUBA3E TUBA3E G3R5R0_GORGO G3R5R0_GORGO G3R6A2_GORGO G3R6A2_GORGO SEH1L SEH1L HDAC8 HDAC8 RAD21 RAD21 MEIOC MEIOC TCERG1L TCERG1L NUP107 NUP107 G3RA54_GORGO G3RA54_GORGO CDK1 CDK1 PPP2CB PPP2CB NDE1 NDE1 DSN1 DSN1 CENPL CENPL G3RGY3_GORGO G3RGY3_GORGO NUDC NUDC DYNC1LI1 DYNC1LI1 B9D2 B9D2 TUBB1 TUBB1 SKA1 SKA1 G3RMA0_GORGO G3RMA0_GORGO G3RP17_GORGO G3RP17_GORGO G3RPS1_GORGO G3RPS1_GORGO RAD21L1 RAD21L1 G3RQF7_GORGO G3RQF7_GORGO CDC20B CDC20B G3RT90_GORGO G3RT90_GORGO ZW10 ZW10 G3RVF4_GORGO G3RVF4_GORGO MC1R MC1R CENPQ CENPQ G3S0Z1_GORGO G3S0Z1_GORGO RPS27 RPS27 KNL1 KNL1 PPP2R5C PPP2R5C ENSGGOP00000030111 ENSGGOP00000030111 ENSGGOP00000029335 ENSGGOP00000029335 TUBA8 TUBA8 KIF2C KIF2C G3SHN3_GORGO G3SHN3_GORGO NUP98 NUP98 CENPU CENPU CENPA CENPA RANGAP1 RANGAP1 KNTC1 KNTC1 SPC25 SPC25 G3SAY3_GORGO G3SAY3_GORGO G3SA94_GORGO G3SA94_GORGO BUB3 BUB3 TUBAL3 TUBAL3 MAPRE1 MAPRE1 NDEL1 NDEL1 G3S5H5_GORGO G3S5H5_GORGO WAPL WAPL TUBB8 TUBB8 MAPRE2 MAPRE2 TUBA3C TUBA3C ERCC6L ERCC6L DYNLL2 DYNLL2 NUP133 NUP133 G3S0Z6_GORGO G3S0Z6_GORGO WDR41 WDR41 ENSGGOP00000050731 ENSGGOP00000050731 ENSGGOP00000050659 ENSGGOP00000050659 CENPE CENPE ENSGGOP00000050000 ENSGGOP00000050000 ENSGGOP00000049876 ENSGGOP00000049876 ENSGGOP00000048713 ENSGGOP00000048713 ENSGGOP00000047617 ENSGGOP00000047617 PPP2R5E PPP2R5E BUB1 BUB1 ENSGGOP00000046635 ENSGGOP00000046635 ENSGGOP00000045437 ENSGGOP00000045437 CENPM CENPM CENPO CENPO XPO1 XPO1 MAD1L1 MAD1L1 KIF2A KIF2A MTUS2 MTUS2 ENSGGOP00000043386 ENSGGOP00000043386 ENSGGOP00000043030 ENSGGOP00000043030 CKAP5 CKAP5 ENSGGOP00000042635 ENSGGOP00000042635 ENSGGOP00000042553 ENSGGOP00000042553 INCENP INCENP ENSGGOP00000042364 ENSGGOP00000042364 MAPRE3 MAPRE3 ENSGGOP00000041443 ENSGGOP00000041443 ENSGGOP00000041427 ENSGGOP00000041427 ENSGGOP00000040881 ENSGGOP00000040881 DYNLL1 DYNLL1 ENSGGOP00000039818 ENSGGOP00000039818 SGO2 SGO2 STAG1 STAG1 SPDL1 SPDL1 TUBA4A TUBA4A PPP1CC PPP1CC CENPP CENPP ENSGGOP00000035259 ENSGGOP00000035259 ENSGGOP00000034276 ENSGGOP00000034276 G3S631_GORGO G3S631_GORGO PPP2R5A PPP2R5A ENSGGOP00000032612 ENSGGOP00000032612 AHCTF1 AHCTF1 DYNC1I2 DYNC1I2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000035777Baculoviral IAP repeat containing 5. (165 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4646 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
NUP160Nucleoporin 160. (1436 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (307 aa)
CENPTCentromere protein T. (561 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
CENPHCentromere protein H. (247 aa)
G3QI01_GORGOCAP-Gly domain containing linker protein 1. (1438 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1068 aa)
G3QIQ6_GORGOTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
CENPFCentromere protein F. (3057 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
ERCC6L2ERCC excision repair 6 like 2. (712 aa)
G3QK51_GORGOCentromere protein N. (315 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
ZWILCHZwilch kinetochore protein. (571 aa)
STAG2Stromal antigen 2. (1268 aa)
NUP37Nucleoporin 37. (326 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (215 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (475 aa)
PDS5BPDS5 cohesin associated factor B. (1448 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (373 aa)
CENPKCentromere protein K. (269 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (456 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
SGO1Shugoshin 1. (527 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (673 aa)
TAOK1TAO kinase 1. (1001 aa)
ZWINTZW10 interacting kinetochore protein. (279 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
NUP43Nucleoporin 43. (380 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
CDCA8Cell division cycle associated 8. (280 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
G3QYL5_GORGOTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa)
SPC24Uncharacterized protein. (209 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1393 aa)
CENPCCentromere protein C. (943 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
G3R428_GORGOProtein phosphatase 2 scaffold subunit Abeta. (620 aa)
CDC20Cell division cycle 20. (499 aa)
MIS12MIS12 kinetochore complex component. (205 aa)
TUBA3ETubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (374 aa)
G3R5R0_GORGOPolyamine modulated factor 1. (207 aa)
G3R6A2_GORGOUncharacterized protein. (439 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
RAD21RAD21 cohesin complex component. (631 aa)
MEIOCMeiosis specific with coiled-coil domain. (952 aa)
TCERG1LTranscription elongation regulator 1 like. (491 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
G3RA54_GORGOCentromere protein I. (669 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
NDE1NudE neurodevelopment protein 1. (335 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (356 aa)
CENPLCentromere protein L. (390 aa)
G3RGY3_GORGORegulator of chromosome condensation 2. (515 aa)
NUDCNuclear distribution C, dynein complex regulator. (332 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (497 aa)
B9D2B9 domain containing 2. (175 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
G3RMA0_GORGOTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
G3RP17_GORGOStructural maintenance of chromosomes protein. (1175 aa)
G3RPS1_GORGOWD_REPEATS_REGION domain-containing protein. (457 aa)
RAD21L1RAD21 cohesin complex component like 1. (556 aa)
G3RQF7_GORGOTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CDC20BCell division cycle 20B. (519 aa)
G3RT90_GORGOHORMA domain-containing protein. (143 aa)
ZW10Zw10 kinetochore protein. (779 aa)
G3RVF4_GORGOUncharacterized protein; Belongs to the tubulin family. (444 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). (794 aa)
CENPQCentromere protein Q. (268 aa)
G3S0Z1_GORGODynein light chain. (91 aa)
RPS2740S ribosomal protein S27. (84 aa)
KNL1Kinetochore scaffold 1. (2342 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (472 aa)
ENSGGOP00000030111Protein kinase domain-containing protein. (210 aa)
ENSGGOP00000029335Tubulin alpha 4b. (235 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (559 aa)
G3SHN3_GORGOTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa)
NUP98Nucleoporin 98. (1817 aa)
CENPUCentromere protein U. (421 aa)
CENPACentromere protein A. (140 aa)
RANGAP1Ran GTPase activating protein 1. (628 aa)
KNTC1Kinetochore associated 1. (2209 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (224 aa)
G3SAY3_GORGO40S ribosomal protein S27. (84 aa)
G3SA94_GORGOCell division cycle associated 5. (262 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
MAPRE1Uncharacterized protein. (268 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
G3S5H5_GORGOUncharacterized protein. (838 aa)
WAPLWAPL cohesin release factor. (1190 aa)
TUBB8Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (327 aa)
TUBA3CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1249 aa)
DYNLL2Uncharacterized protein. (183 aa)
NUP133Nucleoporin 133. (1156 aa)
G3S0Z6_GORGO40S ribosomal protein S27. (84 aa)
WDR41WD repeat domain 41. (459 aa)
ENSGGOP00000050731Tubulin domain-containing protein. (119 aa)
ENSGGOP00000050659Uncharacterized protein; Belongs to the cyclin family. (347 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
ENSGGOP00000050000Uncharacterized protein. (108 aa)
ENSGGOP00000049876annotation not available (227 aa)
ENSGGOP00000048713Uncharacterized protein. (227 aa)
ENSGGOP00000047617SKA2 domain-containing protein. (92 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (423 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1094 aa)
ENSGGOP00000046635Uncharacterized protein; Belongs to the tubulin family. (423 aa)
ENSGGOP00000045437Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (575 aa)
CENPMCentromere protein M. (180 aa)
CENPOCentromere protein O. (300 aa)
XPO1Exportin 1. (1071 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (699 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (734 aa)
MTUS2Uncharacterized protein. (143 aa)
ENSGGOP00000043386Uncharacterized protein. (1478 aa)
ENSGGOP00000043030Serine/threonine-protein kinase PLK. (624 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
ENSGGOP00000042635Calponin-homology (CH) domain-containing protein. (252 aa)
ENSGGOP00000042553Uncharacterized protein. (260 aa)
INCENPInner centromere protein. (903 aa)
ENSGGOP00000042364CAP-Gly domain containing linker protein 2. (1068 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
ENSGGOP00000041443WD_REPEATS_REGION domain-containing protein. (285 aa)
ENSGGOP00000041427Cytoplasmic linker associated protein 1. (1538 aa)
ENSGGOP00000040881Dynein light chain. (72 aa)
DYNLL1Dynein light chain. (89 aa)
ENSGGOP00000039818Tubulin domain-containing protein; Belongs to the tubulin family. (439 aa)
SGO2Shugoshin 2. (1266 aa)
STAG1Stromal antigen 1. (1258 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (346 aa)
CENPPCentromere protein P. (288 aa)
ENSGGOP00000035259Structural maintenance of chromosomes 1A. (1096 aa)
ENSGGOP00000034276Tubulin domain-containing protein. (57 aa)
G3S631_GORGOTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (372 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
ENSGGOP0000003261240S ribosomal protein S27. (84 aa)
AHCTF1AT-hook containing transcription factor 1. (2301 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (650 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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