STRINGSTRING
PSEN1 PSEN1 PSEN2 PSEN2 NOTCH2 NOTCH2 G3QQC0_GORGO G3QQC0_GORGO DLL1 DLL1 G3QXA1_GORGO G3QXA1_GORGO RPS27A RPS27A G3R524_GORGO G3R524_GORGO MIB1 MIB1 PSENEN PSENEN APH1A APH1A ENSGGOP00000019740 ENSGGOP00000019740 JAG1 JAG1 MDK MDK NEURL1 NEURL1 G3SEP4_GORGO G3SEP4_GORGO DLL4 DLL4 CNTN1 CNTN1 ENSGGOP00000038520 ENSGGOP00000038520 APH1B APH1B ENSGGOP00000045153 ENSGGOP00000045153 NCSTN NCSTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
NOTCH2Notch receptor 2. (2373 aa)
G3QQC0_GORGOUncharacterized protein. (315 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
G3QXA1_GORGODelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1199 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
G3R524_GORGOADAM metallopeptidase domain 10. (705 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSGGOP00000019740annotation not available (156 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
MDKMidkine. (143 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
CNTN1Contactin 1. (1028 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ENSGGOP00000045153Mindbomb E3 ubiquitin protein ligase 2. (979 aa)
NCSTNNicastrin. (721 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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