21 items (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3QL18_GORGO	Uncharacterized protein. (453 aa)
	NFYA	Nuclear transcription factor Y subunit alpha. (347 aa)
	ENSGGOP00000039694	CBFD_NFYB_HMF domain-containing protein. (301 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	ATF6B	Activating transcription factor 6 beta. (703 aa)
	ENSGGOP00000034184	CBFD_NFYB_HMF domain-containing protein. (207 aa)
	ENSGGOP00000033934	Uncharacterized protein. (318 aa)
	ENSGGOP00000033459	BZIP domain-containing protein. (350 aa)
	ENSGGOP00000032087	BZIP domain-containing protein. (342 aa)
	G3SHK6_GORGO	Uncharacterized protein. (508 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (814 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	G3RPU5_GORGO	Uncharacterized protein; Belongs to the heat shock protein 70 family. (613 aa)
	CALR	Calreticulin. (417 aa)
	ATF6	Activating transcription factor 6. (670 aa)
	MBTPS2	Membrane bound transcription factor peptidase, site 2. (520 aa)
	MBTPS1	Membrane bound transcription factor peptidase, site 1. (1052 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	NFYB	Nuclear transcription factor Y subunit beta. (169 aa)
	G3QWP0_GORGO	Nuclear transcription factor Y subunit gamma. (458 aa)
	DDIT3	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	ATF6	ENSGGOP00000009869	ENSGGOP00000013473	Activating transcription factor 4.	Activating transcription factor 6.	0.554
ATF4	ATF6B	ENSGGOP00000009869	ENSGGOP00000038216	Activating transcription factor 4.	Activating transcription factor 6 beta.	0.921
ATF4	DDIT3	ENSGGOP00000009869	ENSGGOP00000001955	Activating transcription factor 4.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.979
ATF4	ENSGGOP00000032087	ENSGGOP00000009869	ENSGGOP00000032087	Activating transcription factor 4.	BZIP domain-containing protein.	0.543
ATF4	ENSGGOP00000033459	ENSGGOP00000009869	ENSGGOP00000033459	Activating transcription factor 4.	BZIP domain-containing protein.	0.545
ATF4	ENSGGOP00000033934	ENSGGOP00000009869	ENSGGOP00000033934	Activating transcription factor 4.	Uncharacterized protein.	0.545
ATF4	G3RPU5_GORGO	ENSGGOP00000009869	ENSGGOP00000017817	Activating transcription factor 4.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.656
ATF4	HSPA5	ENSGGOP00000009869	ENSGGOP00000023678	Activating transcription factor 4.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.768
ATF4	XBP1	ENSGGOP00000009869	ENSGGOP00000038457	Activating transcription factor 4.	BZIP domain-containing protein.	0.580
ATF6	ATF4	ENSGGOP00000013473	ENSGGOP00000009869	Activating transcription factor 6.	Activating transcription factor 4.	0.554
ATF6	ATF6B	ENSGGOP00000013473	ENSGGOP00000038216	Activating transcription factor 6.	Activating transcription factor 6 beta.	0.932
ATF6	CALR	ENSGGOP00000013473	ENSGGOP00000015732	Activating transcription factor 6.	Calreticulin.	0.786
ATF6	DDIT3	ENSGGOP00000013473	ENSGGOP00000001955	Activating transcription factor 6.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.986
ATF6	ENSGGOP00000032087	ENSGGOP00000013473	ENSGGOP00000032087	Activating transcription factor 6.	BZIP domain-containing protein.	0.554
ATF6	ENSGGOP00000033459	ENSGGOP00000013473	ENSGGOP00000033459	Activating transcription factor 6.	BZIP domain-containing protein.	0.554
ATF6	ENSGGOP00000033934	ENSGGOP00000013473	ENSGGOP00000033934	Activating transcription factor 6.	Uncharacterized protein.	0.513
ATF6	G3QL18_GORGO	ENSGGOP00000013473	ENSGGOP00000003159	Activating transcription factor 6.	Uncharacterized protein.	0.465
ATF6	G3RPU5_GORGO	ENSGGOP00000013473	ENSGGOP00000017817	Activating transcription factor 6.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.963
ATF6	G3SHK6_GORGO	ENSGGOP00000013473	ENSGGOP00000027595	Activating transcription factor 6.	Uncharacterized protein.	0.800
ATF6	HSP90B1	ENSGGOP00000013473	ENSGGOP00000025114	Activating transcription factor 6.	Heat shock protein 90 beta family member 1.	0.851