STRINGSTRING
G3RBE1_GORGO G3RBE1_GORGO PLA2G4A PLA2G4A GUCY1A1 GUCY1A1 SLC8A2 SLC8A2 PECAM1 PECAM1 G3R530_GORGO G3R530_GORGO ATP2B4 ATP2B4 G3R428_GORGO G3R428_GORGO G3R3U8_GORGO G3R3U8_GORGO P2RX2 P2RX2 P2RX5 P2RX5 GUCY1A2 GUCY1A2 TRPC6 TRPC6 ATP2A1 ATP2A1 PDE1B PDE1B GNG4 GNG4 PPP2R5D PPP2R5D ATP2B3 ATP2B3 KCNMB1 KCNMB1 PPP2R1A PPP2R1A PRKG2 PRKG2 G3QU42_GORGO G3QU42_GORGO ITPR1 ITPR1 G3QRP1_GORGO G3QRP1_GORGO TRPC3 TRPC3 REEP4 REEP4 G3QN57_GORGO G3QN57_GORGO G3QM33_GORGO G3QM33_GORGO G3QLY6_GORGO G3QLY6_GORGO GNG3 GNG3 GNAS GNAS GNB3 GNB3 ATP2A3 ATP2A3 G3QFE2_GORGO G3QFE2_GORGO REEP2 REEP2 SRI SRI FGR FGR PPP2R5B PPP2R5B PPP2CA PPP2CA CALM3 CALM3 ATP2B4-2 ATP2B4-2 ENSGGOP00000049072 ENSGGOP00000049072 PRKG1 PRKG1 PDE1A PDE1A PPP2R5E PPP2R5E ENSGGOP00000045437 ENSGGOP00000045437 GNG7 GNG7 GNGT2 GNGT2 ENSGGOP00000044555 ENSGGOP00000044555 ENSGGOP00000043921 ENSGGOP00000043921 ENSGGOP00000043797 ENSGGOP00000043797 ENSGGOP00000042553 ENSGGOP00000042553 ENSGGOP00000040681 ENSGGOP00000040681 GNB2 GNB2 P2RX3 P2RX3 PDE10A PDE10A ITPR2 ITPR2 GNG13 GNG13 ENSGGOP00000037657 ENSGGOP00000037657 ENSGGOP00000037095 ENSGGOP00000037095 ENSGGOP00000036661 ENSGGOP00000036661 ENSGGOP00000036103 ENSGGOP00000036103 GNB1 GNB1 ENSGGOP00000035322 ENSGGOP00000035322 SLC8A3 SLC8A3 ENSGGOP00000034163 ENSGGOP00000034163 GUCY1B1 GUCY1B1 ATP2A2 ATP2A2 PPP2R5A PPP2R5A ENSGGOP00000031606 ENSGGOP00000031606 TRPC7 TRPC7 ENSGGOP00000031235 ENSGGOP00000031235 GNG12 GNG12 PPP2R5C PPP2R5C GNG2 GNG2 PDE11A PDE11A PTPN11 PTPN11 NOS1 NOS1 G3SEV0_GORGO G3SEV0_GORGO G3SBY4_GORGO G3SBY4_GORGO GNB4 GNB4 ITPR3 ITPR3 P2RX1 P2RX1 APOB APOB MRVI1 MRVI1 G3RRP1_GORGO G3RRP1_GORGO NOS2 NOS2 REEP3 REEP3 NOS3 NOS3 ORAI2 ORAI2 KCNMB2 KCNMB2 GNGT1 GNGT1 GNG11 GNG11 PDE2A PDE2A PDE9A PDE9A PAFAH2 PAFAH2 ATP2B1 ATP2B1 PTPN6 PTPN6 PPP2CB PPP2CB G3RD86_GORGO G3RD86_GORGO PDE5A PDE5A KCNMB4 KCNMB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3RBE1_GORGOProstaglandin I2 receptor. (386 aa)
PLA2G4APhospholipase A2. (749 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (738 aa)
G3R530_GORGOGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (49 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1225 aa)
G3R428_GORGOProtein phosphatase 2 scaffold subunit Abeta. (620 aa)
G3R3U8_GORGOCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (411 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (428 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (753 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (795 aa)
PDE1BPhosphodiesterase. (536 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
G3QU42_GORGOUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (791 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2706 aa)
G3QRP1_GORGOUncharacterized protein. (107 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
G3QN57_GORGOLDL receptor related protein 8. (964 aa)
G3QM33_GORGOUncharacterized protein. (3189 aa)
G3QLY6_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (441 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNASGNAS complex locus. (985 aa)
GNB3G protein subunit beta 3. (340 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1051 aa)
G3QFE2_GORGOG protein subunit beta 5. (394 aa)
REEP2Receptor expression-enhancing protein. (214 aa)
SRISorcin. (198 aa)
FGRTyrosine-protein kinase. (529 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ATP2B4-2Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (554 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PDE1APhosphodiesterase. (545 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (423 aa)
ENSGGOP00000045437Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (575 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
ENSGGOP00000044555Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
ENSGGOP00000043921P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
ENSGGOP00000043797Potassium calcium-activated channel subfamily M alpha 1. (1162 aa)
ENSGGOP00000042553Uncharacterized protein. (260 aa)
ENSGGOP00000040681Uncharacterized protein; Belongs to the calmodulin family. (70 aa)
GNB2G protein subunit beta 2. (340 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
PDE10APhosphodiesterase. (789 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ENSGGOP00000037657Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ENSGGOP00000037095Uncharacterized protein. (575 aa)
ENSGGOP00000036661Uncharacterized protein. (87 aa)
ENSGGOP00000036103Uncharacterized protein. (509 aa)
GNB1G protein subunit beta 1. (340 aa)
ENSGGOP00000035322XRCC1_N domain-containing protein. (142 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ENSGGOP00000034163Uncharacterized protein. (485 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
ENSGGOP00000031606Stromal interaction molecule 1. (791 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
ENSGGOP00000031235Uncharacterized protein; Belongs to the calmodulin family. (129 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (472 aa)
GNG2G protein gamma domain-containing protein. (41 aa)
PDE11APhosphodiesterase. (933 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
G3SEV0_GORGOUncharacterized protein; Belongs to the calmodulin family. (152 aa)
G3SBY4_GORGOORAI calcium release-activated calcium modulator 3. (295 aa)
GNB4G protein subunit beta 4. (340 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
APOBApolipoprotein B. (4566 aa)
MRVI1Murine retrovirus integration site 1 homolog. (861 aa)
G3RRP1_GORGOUncharacterized protein. (270 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
REEP3Receptor expression-enhancing protein. (255 aa)
NOS3Nitric oxide synthase 3. (997 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (254 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PDE2APhosphodiesterase. (941 aa)
PDE9APhosphodiesterase. (505 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
G3RD86_GORGOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PDE5APhosphodiesterase. (875 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (26%) [HD]