STRINGSTRING
PPP2CA PPP2CA FOS FOS MAP2K3 MAP2K3 UBC UBC IL17RB IL17RB G3QHL6_GORGO G3QHL6_GORGO RPS6KA1 RPS6KA1 MAP2K1 MAP2K1 RPS6KA5 RPS6KA5 UBA52 UBA52 IKBKG IKBKG IL17F IL17F MAP3K8 MAP3K8 G3QSG6_GORGO G3QSG6_GORGO TRAF6 TRAF6 DUSP4 DUSP4 MAPK7 MAPK7 PPP4R1 PPP4R1 PPP2R1A PPP2R1A IKBKB IKBKB PPP2R5D PPP2R5D RPS27A RPS27A G3QXZ2_GORGO G3QXZ2_GORGO MAPK15 MAPK15 TAB1 TAB1 ELK1 ELK1 RPS6KA3 RPS6KA3 CHUK CHUK FOSL2 FOSL2 IL17A IL17A G3R428_GORGO G3R428_GORGO NOD2 NOD2 RIPK2 RIPK2 IL17RE IL17RE G3R905_GORGO G3R905_GORGO IL17C IL17C PPP2CB PPP2CB FNBP4 FNBP4 MAPKAPK3 MAPKAPK3 RELCH RELCH G3RGS2_GORGO G3RGS2_GORGO G3RHM6_GORGO G3RHM6_GORGO TAB2 TAB2 IRAK1 IRAK1 NFKB1 NFKB1 TAB3 TAB3 ENSGGOP00000019740 ENSGGOP00000019740 MAP3K7 MAP3K7 BTRC BTRC SKP1 SKP1 IL17RA IL17RA MAPK3 MAPK3 NOD1 NOD1 MAPK11 MAPK11 MAPK9 MAPK9 MAP2K6 MAP2K6 VRK3 VRK3 DUSP6 DUSP6 MEF2A MEF2A G3SEP4_GORGO G3SEP4_GORGO DUSP3 DUSP3 DUSP7 DUSP7 ENSGGOP00000030202 ENSGGOP00000030202 ENSGGOP00000031261 ENSGGOP00000031261 ATF2 ATF2 ENSGGOP00000031801 ENSGGOP00000031801 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000032619 ENSGGOP00000032619 CREM CREM UBE2N UBE2N RPS6KA2 RPS6KA2 ENSGGOP00000034513 ENSGGOP00000034513 ENSGGOP00000034747 ENSGGOP00000034747 ENSGGOP00000035103 ENSGGOP00000035103 ENSGGOP00000035952 ENSGGOP00000035952 ENSGGOP00000038520 ENSGGOP00000038520 IL25 IL25 MAPKAPK2 MAPKAPK2 ENSGGOP00000039123 ENSGGOP00000039123 ENSGGOP00000040207 ENSGGOP00000040207 MAPK1 MAPK1 MAP2K7 MAP2K7 CUL1 CUL1 PPP4R4 PPP4R4 ENSGGOP00000044534 ENSGGOP00000044534 ATF1 ATF1 ENSGGOP00000046510 ENSGGOP00000046510 ENSGGOP00000047060 ENSGGOP00000047060 ENSGGOP00000047423 ENSGGOP00000047423 ENSGGOP00000049072 ENSGGOP00000049072 MAPK8 MAPK8 ENSGGOP00000050590 ENSGGOP00000050590 MAPK10 MAPK10 ENSGGOP00000051849 ENSGGOP00000051849
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
IL17RBInterleukin 17 receptor B. (502 aa)
G3QHL6_GORGOInterleukin 1 receptor associated kinase 2. (538 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
IL17FInterleukin 17F. (163 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
G3QSG6_GORGOMitogen-activated protein kinase kinase kinase 20. (780 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (937 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
G3QXZ2_GORGOF-box and WD repeat domain containing 11. (542 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
ELK1ETS transcription factor ELK1. (452 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CHUKIKKbetaNEMObind domain-containing protein. (434 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (327 aa)
IL17AInterleukin 17A. (155 aa)
G3R428_GORGOProtein phosphatase 2 scaffold subunit Abeta. (620 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
IL17REInterleukin 17 receptor E. (699 aa)
G3R905_GORGOInterleukin 17 receptor C. (787 aa)
IL17CInterleukin 17C. (197 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
FNBP4Formin binding protein 4. (1019 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
G3RGS2_GORGOCyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
G3RHM6_GORGOWRNPLPNID domain-containing protein. (946 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
ENSGGOP00000019740annotation not available (156 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
IL17RAInterleukin 17 receptor A. (865 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (349 aa)
ENSGGOP00000030202Uncharacterized protein. (279 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSGGOP00000031801CCHC NOA-type domain-containing protein. (346 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000032619cAMP responsive element binding protein 1. (341 aa)
CREMcAMP responsive element modulator. (344 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ENSGGOP00000034513Ubiquitin-like domain-containing protein. (156 aa)
ENSGGOP00000034747Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
ENSGGOP00000035103Protein kinase domain-containing protein. (379 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
IL25Interleukin 25. (177 aa)
MAPKAPK2Protein kinase domain-containing protein. (374 aa)
ENSGGOP00000039123CCHC NOA-type domain-containing protein. (371 aa)
ENSGGOP00000040207Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
CUL1Cullin domain-containing protein; Belongs to the cullin family. (323 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (849 aa)
ENSGGOP00000044534Protein kinase domain-containing protein. (363 aa)
ATF1Activating transcription factor 1. (270 aa)
ENSGGOP00000046510Uncharacterized protein; Belongs to the SKP1 family. (164 aa)
ENSGGOP00000047060UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
ENSGGOP00000047423UBIQUITIN_CONJUGAT_2 domain-containing protein. (126 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
ENSGGOP00000051849Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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