STRINGSTRING
ELK1 ELK1 ENSGGOP00000051849 ENSGGOP00000051849 MAPK10 MAPK10 ENSGGOP00000050590 ENSGGOP00000050590 MAPK8 MAPK8 ENSGGOP00000049072 ENSGGOP00000049072 ENSGGOP00000047423 ENSGGOP00000047423 ENSGGOP00000047060 ENSGGOP00000047060 ENSGGOP00000046510 ENSGGOP00000046510 ATF1 ATF1 ENSGGOP00000044534 ENSGGOP00000044534 PPP4R4 PPP4R4 CUL1 CUL1 MAP2K7 MAP2K7 MAPK1 MAPK1 ENSGGOP00000040207 ENSGGOP00000040207 ENSGGOP00000039123 ENSGGOP00000039123 MAPKAPK2 MAPKAPK2 ENSGGOP00000038520 ENSGGOP00000038520 ENSGGOP00000035952 ENSGGOP00000035952 ENSGGOP00000035103 ENSGGOP00000035103 ENSGGOP00000034747 ENSGGOP00000034747 ENSGGOP00000034513 ENSGGOP00000034513 RPS6KA2 RPS6KA2 UBE2N UBE2N CREM CREM ENSGGOP00000032619 ENSGGOP00000032619 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000031801 ENSGGOP00000031801 ATF2 ATF2 ENSGGOP00000031261 ENSGGOP00000031261 ENSGGOP00000030202 ENSGGOP00000030202 DUSP7 DUSP7 DUSP3 DUSP3 G3SEP4_GORGO G3SEP4_GORGO MEF2A MEF2A DUSP6 DUSP6 VRK3 VRK3 MAP2K6 MAP2K6 MAPK9 MAPK9 MAPK11 MAPK11 NOD1 NOD1 MAPK3 MAPK3 SKP1 SKP1 BTRC BTRC MAP3K7 MAP3K7 ENSGGOP00000019740 ENSGGOP00000019740 TAB3 TAB3 NFKB1 NFKB1 IRAK1 IRAK1 TAB2 TAB2 G3RHM6_GORGO G3RHM6_GORGO G3RGS2_GORGO G3RGS2_GORGO RELCH RELCH MAPKAPK3 MAPKAPK3 FNBP4 FNBP4 PPP2CB PPP2CB RIPK2 RIPK2 NOD2 NOD2 G3R428_GORGO G3R428_GORGO FOSL2 FOSL2 CHUK CHUK RPS6KA3 RPS6KA3 TAB1 TAB1 MAPK15 MAPK15 G3QXZ2_GORGO G3QXZ2_GORGO RPS27A RPS27A PPP2R5D PPP2R5D IKBKB IKBKB PPP2R1A PPP2R1A PPP4R1 PPP4R1 MAPK7 MAPK7 DUSP4 DUSP4 TRAF6 TRAF6 G3QSG6_GORGO G3QSG6_GORGO MAP3K8 MAP3K8 IKBKG IKBKG UBA52 UBA52 RPS6KA5 RPS6KA5 MAP2K1 MAP2K1 RPS6KA1 RPS6KA1 G3QHL6_GORGO G3QHL6_GORGO UBC UBC MAP2K3 MAP2K3 FOS FOS PPP2CA PPP2CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELK1ETS transcription factor ELK1. (452 aa)
ENSGGOP00000051849Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSGGOP00000049072Protein kinase domain-containing protein. (296 aa)
ENSGGOP00000047423UBIQUITIN_CONJUGAT_2 domain-containing protein. (126 aa)
ENSGGOP00000047060UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
ENSGGOP00000046510Uncharacterized protein; Belongs to the SKP1 family. (164 aa)
ATF1Activating transcription factor 1. (270 aa)
ENSGGOP00000044534Protein kinase domain-containing protein. (363 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (849 aa)
CUL1Cullin domain-containing protein; Belongs to the cullin family. (323 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSGGOP00000040207Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa)
ENSGGOP00000039123CCHC NOA-type domain-containing protein. (371 aa)
MAPKAPK2Protein kinase domain-containing protein. (374 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
ENSGGOP00000035103Protein kinase domain-containing protein. (379 aa)
ENSGGOP00000034747Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
ENSGGOP00000034513Ubiquitin-like domain-containing protein. (156 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
CREMcAMP responsive element modulator. (344 aa)
ENSGGOP00000032619cAMP responsive element binding protein 1. (341 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000031801CCHC NOA-type domain-containing protein. (346 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSGGOP00000031261Myocyte enhancer factor 2C. (483 aa)
ENSGGOP00000030202Uncharacterized protein. (279 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (349 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
VRK3VRK serine/threonine kinase 3. (474 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
ENSGGOP00000019740annotation not available (156 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (712 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
G3RHM6_GORGOWRNPLPNID domain-containing protein. (946 aa)
G3RGS2_GORGOCyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
FNBP4Formin binding protein 4. (1019 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
G3R428_GORGOProtein phosphatase 2 scaffold subunit Abeta. (620 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (327 aa)
CHUKIKKbetaNEMObind domain-containing protein. (434 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
G3QXZ2_GORGOF-box and WD repeat domain containing 11. (542 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (937 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
G3QSG6_GORGOMitogen-activated protein kinase kinase kinase 20. (780 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
G3QHL6_GORGOInterleukin 1 receptor associated kinase 2. (538 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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