STRINGSTRING
RIPK1 RIPK1 RNF31 RNF31 TAB2 TAB2 TAB3 TAB3 ENSGGOP00000019740 ENSGGOP00000019740 SHARPIN SHARPIN MAP3K7 MAP3K7 G3SEP4_GORGO G3SEP4_GORGO TNFRSF1A TNFRSF1A OTUD7B OTUD7B ENSGGOP00000031106 ENSGGOP00000031106 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000032772 ENSGGOP00000032772 OPTN OPTN ENSGGOP00000038520 ENSGGOP00000038520 NAIP NAIP ENSGGOP00000050852 ENSGGOP00000050852 OTUD1 OTUD1 UBC UBC TRAF1 TRAF1 TNFAIP3 TNFAIP3 USP4 USP4 IKBKG IKBKG USP2 USP2 BIRC3 BIRC3 G3QT76_GORGO G3QT76_GORGO IKBKB IKBKB TRAF2 TRAF2 G3QX09_GORGO G3QX09_GORGO BIRC8 BIRC8 RPS27A RPS27A TAB1 TAB1 BIRC2 BIRC2 BIRC7 BIRC7 CYLD CYLD XIAP XIAP RBCK1 RBCK1 CHUK CHUK TRADD TRADD G3RI71_GORGO G3RI71_GORGO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
RNF31Uncharacterized protein. (1072 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
ENSGGOP00000019740annotation not available (156 aa)
SHARPINSHANK associated RH domain interactor. (387 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
OTUD7BOTU deubiquitinase 7B. (843 aa)
ENSGGOP00000031106WD_REPEATS_REGION domain-containing protein. (321 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000032772Uncharacterized protein. (104 aa)
OPTNOptineurin. (577 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
NAIPUncharacterized protein. (198 aa)
ENSGGOP00000050852annotation not available (362 aa)
OTUD1OTU deubiquitinase 1. (481 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
TRAF1TNF receptor-associated factor. (416 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (773 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
G3QT76_GORGOTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (762 aa)
TRAF2TNF receptor-associated factor. (451 aa)
G3QX09_GORGOUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa)
BIRC8Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (236 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
XIAPUncharacterized protein. (371 aa)
RBCK1Uncharacterized protein. (204 aa)
CHUKIKKbetaNEMObind domain-containing protein. (434 aa)
TRADDDeath domain-containing protein. (251 aa)
G3RI71_GORGONACHT domain-containing protein. (1127 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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