STRINGSTRING
ENSGGOP00000039123 ENSGGOP00000039123 OTUD5 OTUD5 TNIP1 TNIP1 ENSGGOP00000050360 ENSGGOP00000050360 ENSGGOP00000050590 ENSGGOP00000050590 RNF128 RNF128 RNF167 RNF167 SPATA5 SPATA5 PTEN PTEN UBC UBC G3QJ42_GORGO G3QJ42_GORGO ZNRF4 ZNRF4 APC2 APC2 VCP VCP TNFAIP3 TNFAIP3 OTUD3 OTUD3 TRAF3 TRAF3 UBA52 UBA52 IKBKG IKBKG TRAF6 TRAF6 RNF135 RNF135 YOD1 YOD1 RNF13 RNF13 RPS27A RPS27A OTUD7A OTUD7A ESR1 ESR1 G3R3U7_GORGO G3R3U7_GORGO NOD2 NOD2 RIPK2 RIPK2 TRIM25 TRIM25 OTUB1 OTUB1 RIPK1 RIPK1 TRAF5 TRAF5 RHOA RHOA CDK1 CDK1 IFIH1 IFIH1 ZRANB1 ZRANB1 G3RNB7_GORGO G3RNB7_GORGO TNIP3 TNIP3 APC APC ENSGGOP00000019740 ENSGGOP00000019740 NOD1 NOD1 SPATA5L1 SPATA5L1 DDX58 DDX58 CCDC197 CCDC197 GUF1 GUF1 G3SEP4_GORGO G3SEP4_GORGO VCPIP1 VCPIP1 OTUD7B OTUD7B TP53 TP53 ENSGGOP00000031801 ENSGGOP00000031801 OTUB2 OTUB2 ENSGGOP00000032596 ENSGGOP00000032596 ENSGGOP00000034513 ENSGGOP00000034513 ENSGGOP00000035952 ENSGGOP00000035952 UBE2D1 UBE2D1 ENSGGOP00000038498 ENSGGOP00000038498 ENSGGOP00000038520 ENSGGOP00000038520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSGGOP00000039123CCHC NOA-type domain-containing protein. (371 aa)
OTUD5OTU domain-containing protein. (204 aa)
TNIP1TNFAIP3 interacting protein 1. (645 aa)
ENSGGOP00000050360RING-type domain-containing protein. (320 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
RNF128RING-type domain-containing protein. (402 aa)
RNF167Ring finger protein 167. (351 aa)
SPATA5Spermatogenesis associated 5. (893 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
G3QJ42_GORGOOTU domain-containing protein. (1058 aa)
ZNRF4Zinc and ring finger 4. (421 aa)
APC2APC regulator of WNT signaling pathway 2. (2289 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
OTUD3OTU deubiquitinase 3. (398 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
RNF135Ring finger protein 135. (372 aa)
YOD1YOD1 deubiquitinase. (348 aa)
RNF13Ring finger protein 13. (381 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
OTUD7AOTU deubiquitinase 7A. (926 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
G3R3U7_GORGOMitochondrial antiviral signaling protein. (481 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
TRIM25Tripartite motif containing 25. (630 aa)
OTUB1OTU domain-containing protein. (198 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
RHOAUncharacterized protein. (179 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (734 aa)
G3RNB7_GORGOUncharacterized protein. (661 aa)
TNIP3TNFAIP3 interacting protein 3. (376 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
ENSGGOP00000019740annotation not available (156 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
DDX58DExD/H-box helicase 58. (925 aa)
CCDC197Coiled-coil domain containing 197. (273 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
VCPIP1Valosin containing protein interacting protein 1. (1225 aa)
OTUD7BOTU deubiquitinase 7B. (843 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (403 aa)
ENSGGOP00000031801CCHC NOA-type domain-containing protein. (346 aa)
OTUB2Ubiquitin thioesterase. (265 aa)
ENSGGOP00000032596CCHC NOA-type domain-containing protein. (417 aa)
ENSGGOP00000034513Ubiquitin-like domain-containing protein. (156 aa)
ENSGGOP00000035952TNF receptor-associated factor. (485 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSGGOP00000038498Tripartite motif containing 4. (500 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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