Your Input: | |
| | ENSGGOP00000035952 | TNF receptor-associated factor. (485 aa) |
| | G3SC71_GORGO | Uncharacterized protein. (420 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | SPATA2 | Spermatogenesis associated 2. (520 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | G3S4X5_GORGO | MAGE family member D1. (834 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | NET1 | Neuroepithelial cell transforming 1. (599 aa) |
| | ECT2 | Epithelial cell transforming 2. (914 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | G3S0J3_GORGO | DUF4203 domain-containing protein. (106 aa) |
| | G3RYA7_GORGO | Uncharacterized protein. (382 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (387 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | G3RVX1_GORGO | Uncharacterized protein. (547 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | ENSGGOP00000019740 | annotation not available (156 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | RTN4 | Reticulon. (1192 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | APH1A | Aph-1 homolog A, gamma-secretase subunit. (265 aa) |
| | ABR | ABR activator of RhoGEF and GTPase. (859 aa) |
| | PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | TGM6 | Transglutaminase 6. (703 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | G3RI71_GORGO | NACHT domain-containing protein. (1127 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (948 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | G3RDU1_GORGO | MCF.2 cell line derived transforming sequence like. (1137 aa) |
| | OTULINL | OTU deubiquitinase with linear linkage specificity like. (356 aa) |
| | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa) |
| | G3RCS6_GORGO | Trio Rho guanine nucleotide exchange factor. (2867 aa) |
| | SPPL2A | Signal peptide peptidase like 2A. (520 aa) |
| | LINGO2 | Leucine rich repeat and Ig domain containing 2. (606 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | RHOA | Uncharacterized protein. (179 aa) |
| | ECT2L | Epithelial cell transforming 2 like. (904 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (523 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (788 aa) |
| | G3R907_GORGO | T cell lymphoma invasion and metastasis 2. (1725 aa) |
| | ARHGEF15 | Rho guanine nucleotide exchange factor 15. (841 aa) |
| | TRADD | Death domain-containing protein. (251 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | ARHGEF38 | DH domain-containing protein. (219 aa) |
| | TNFRSF10B | TNF receptor superfamily member 10b. (440 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | G3R515_GORGO | Protein kinase C iota. (557 aa) |
| | LINGO1 | Leucine rich repeat and Ig domain containing 1. (620 aa) |
| | ARHGEF17 | Rho guanine nucleotide exchange factor 17. (2064 aa) |
| | SPPL2B | Signal peptide peptidase like 2B. (511 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | CHUK | IKKbetaNEMObind domain-containing protein. (434 aa) |
| | RBCK1 | Uncharacterized protein. (204 aa) |
| | FGD3 | FYVE, RhoGEF and PH domain containing 3. (725 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (920 aa) |
| | XIAP | Uncharacterized protein. (371 aa) |
| | MADD | MAP kinase activating death domain. (1647 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (298 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | G3QYB0_GORGO | TNF receptor superfamily member 10d. (386 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | FGD1 | FYVE, RhoGEF and PH domain containing 1. (961 aa) |
| | NGEF | Neuronal guanine nucleotide exchange factor. (709 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | BIRC8 | Baculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (236 aa) |
| | G3QX09_GORGO | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa) |
| | ARHGEF40 | Rho guanine nucleotide exchange factor 40. (1517 aa) |
| | TRAF2 | TNF receptor-associated factor. (451 aa) |
| | WDR31 | WD repeat domain 31. (367 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (762 aa) |
| | RTN4R | Reticulon 4 receptor. (472 aa) |
| | G3QT76_GORGO | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1031 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | MCF2L2 | MCF.2 cell line derived transforming sequence-like 2. (1114 aa) |
| | G3QSG6_GORGO | Mitogen-activated protein kinase kinase kinase 20. (780 aa) |
| | G3QRS6_GORGO | FYVE, RhoGEF and PH domain containing 2. (655 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | G3QQ77_GORGO | Neutral sphingomyelinase activation associated factor. (879 aa) |
| | G3QPY2_GORGO | Uncharacterized protein. (1173 aa) |
| | ITGB3BP | Integrin subunit beta 3 binding protein. (215 aa) |
| | UBA52 | Ubiquitin-like domain-containing protein. (233 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (773 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | TMEM198 | Transmembrane protein 198. (360 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (423 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa) |
| | TRAF1 | TNF receptor-associated factor. (416 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (376 aa) |
| | ARHGEF37 | Rho guanine nucleotide exchange factor 37. (675 aa) |
| | KALRN | Uncharacterized protein. (2986 aa) |
| | UBE2D3 | Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (149 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (983 aa) |
| | UBC | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa) |
| | PRDM4 | PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa) |
| | BAG4 | BCL2 associated athanogene 4. (457 aa) |
| | CLIP3 | CAP-Gly domain containing linker protein 3. (547 aa) |
| | SESTD1 | SEC14 and spectrin domain containing 1. (696 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2817 aa) |
| | OTUD1 | OTU deubiquitinase 1. (481 aa) |
| | ENSGGOP00000052157 | annotation not available (92 aa) |
| | ARHGEF9 | Cdc42 guanine nucleotide exchange factor 9. (587 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (551 aa) |
| | ENSGGOP00000051279 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (130 aa) |
| | ENSGGOP00000050852 | annotation not available (362 aa) |
| | ENSGGOP00000050590 | Uncharacterized protein. (258 aa) |
| | UBE2D4 | Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | ARHGEF10 | Rho guanine nucleotide exchange factor 10. (1369 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1504 aa) |
| | NCSTN | Nicastrin. (721 aa) |
| | MAG | Myelin associated glycoprotein. (626 aa) |
| | PLEKHG2 | Pleckstrin homology and RhoGEF domain containing G2. (1386 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | ENSGGOP00000047272 | FYVE, RhoGEF and PH domain containing 4. (856 aa) |
| | G3RF33_GORGO | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (468 aa) |
| | OMG | Oligodendrocyte myelin glycoprotein. (440 aa) |
| | ENSGGOP00000045153 | Mindbomb E3 ubiquitin protein ligase 2. (979 aa) |
| | APH1B | Aph-1 homolog B, gamma-secretase subunit. (257 aa) |
| | ARHGEF3 | Rho guanine nucleotide exchange factor 3. (558 aa) |
| | SMPD3 | Uncharacterized protein. (535 aa) |
| | ULK2 | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1036 aa) |
| | ENSGGOP00000042571 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (92 aa) |
| | NAIP | Uncharacterized protein. (198 aa) |
| | ARHGEF10L | Rho guanine nucleotide exchange factor 10 like. (1277 aa) |
| | UBE2L5 | Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | ARHGEF33 | Rho guanine nucleotide exchange factor 33. (870 aa) |
| | OTULIN | OTU deubiquitinase with linear linkage specificity. (352 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1237 aa) |
| | ENSGGOP00000040427 | Rho GDP dissociation inhibitor alpha. (235 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | ENSGGOP00000039359 | PA domain-containing protein. (463 aa) |
| | MCF2 | MCF.2 cell line derived transforming sequence. (1001 aa) |
| | MAPKAPK2 | Protein kinase domain-containing protein. (374 aa) |
| | ENSGGOP00000038520 | Ubiquitin-like domain-containing protein. (187 aa) |
| | ENSGGOP00000037890 | Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8820 aa) |
| | ARHGEF4 | Rho guanine nucleotide exchange factor 4. (690 aa) |
| | ARHGEF39 | Rho guanine nucleotide exchange factor 39. (335 aa) |
| | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1658 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | OPTN | Optineurin. (577 aa) |
| | ITSN1 | Intersectin 1. (1721 aa) |
| | ENSGGOP00000034513 | Ubiquitin-like domain-containing protein. (156 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) |
| | ENSGGOP00000033404 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | ENSGGOP00000032772 | Uncharacterized protein. (104 aa) |
| | ENSGGOP00000032650 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | ENSGGOP00000032596 | CCHC NOA-type domain-containing protein. (417 aa) |
| | ENSGGOP00000032522 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (203 aa) |
| | BEX3 | Brain expressed X-linked 3. (121 aa) |
| | TAX1BP1 | Tax1 binding protein 1. (779 aa) |
| | ENSGGOP00000031106 | WD_REPEATS_REGION domain-containing protein. (321 aa) |
| | ARHGEF26 | Rho guanine nucleotide exchange factor 26. (871 aa) |
| | ENSGGOP00000030202 | Uncharacterized protein. (279 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (803 aa) |
| | ENSGGOP00000028898 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (195 aa) |
| | ARHGEF16 | Rho guanine nucleotide exchange factor 16. (709 aa) |
| | SPPL2C | Signal peptide peptidase like 2C. (684 aa) |
| | OTUD7B | OTU deubiquitinase 7B. (843 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | G3SHM7_GORGO | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (210 aa) |
| | ARHGEF19 | Rho guanine nucleotide exchange factor 19. (796 aa) |
| | FAS | Fas cell surface death receptor. (340 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5. (1063 aa) |
| | CLIP4 | CAP-Gly domain containing linker protein family member 4. (705 aa) |
| | G3SEP4_GORGO | Ubiquitin-like domain-containing protein. (156 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 35. (479 aa) |
| | G3SDL1_GORGO | Uncharacterized protein. (434 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1562 aa) |
| | AATF | Apoptosis antagonizing transcription factor. (560 aa) |
