STRINGSTRING
G3S4Z2_GORGO G3S4Z2_GORGO CDC37 CDC37 PTPN12 PTPN12 ENSGGOP00000019740 ENSGGOP00000019740 PTPN18 PTPN18 G3RFH4_GORGO G3RFH4_GORGO BTC BTC NRG3 NRG3 RNF41 RNF41 G3QZR8_GORGO G3QZR8_GORGO AKT3 AKT3 RPS27A RPS27A EGF EGF UBA52 UBA52 ERBB2 ERBB2 EREG EREG UBC UBC HBEGF HBEGF USP8 USP8 CUL5 CUL5 ENSGGOP00000030121 ENSGGOP00000030121 ENSGGOP00000032650 ENSGGOP00000032650 AKT2 AKT2 ENSGGOP00000034632 ENSGGOP00000034632 ERBIN ERBIN ERBB3 ERBB3 G3SEP4_GORGO G3SEP4_GORGO ENSGGOP00000038520 ENSGGOP00000038520 EGFR EGFR NRG1 NRG1 ERBB4 ERBB4 NRG4 NRG4 ENSGGOP00000043974 ENSGGOP00000043974 ENSGGOP00000046735 ENSGGOP00000046735 ENSGGOP00000050590 ENSGGOP00000050590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3S4Z2_GORGOUncharacterized protein. (119 aa)
CDC37Cell division cycle 37. (378 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa)
ENSGGOP00000019740annotation not available (156 aa)
PTPN18Protein tyrosine phosphatase non-receptor type 18. (458 aa)
G3RFH4_GORGOTyrosine-protein kinase. (508 aa)
BTCBetacellulin. (178 aa)
NRG3Neuregulin 3. (720 aa)
RNF41Ring finger protein 41. (317 aa)
G3QZR8_GORGOUncharacterized protein. (533 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa)
UBA52Ubiquitin-like domain-containing protein. (233 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
EREGEGF-like domain-containing protein. (222 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (315 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
ENSGGOP00000030121Uncharacterized protein. (354 aa)
ENSGGOP00000032650STIP1 homology and U-box containing protein 1. (303 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSGGOP00000034632Recep_L_domain domain-containing protein. (183 aa)
ERBINErbb2 interacting protein. (1419 aa)
ERBB3Protein kinase domain-containing protein. (593 aa)
G3SEP4_GORGOUbiquitin-like domain-containing protein. (156 aa)
ENSGGOP00000038520Ubiquitin-like domain-containing protein. (187 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
NRG1Neuregulin 1. (713 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
NRG4Neuregulin 4. (117 aa)
ENSGGOP00000043974Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (947 aa)
ENSGGOP00000046735Non-specific serine/threonine protein kinase. (524 aa)
ENSGGOP00000050590Uncharacterized protein. (258 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.