(14 nodes) Interleukin-35 Signalling network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL12RB2	Interleukin 12 receptor subunit beta 2. (862 aa)
	CANX	Calnexin. (592 aa)
	ENSGGOP00000049122	Uncharacterized protein. (305 aa)
	ENSGGOP00000048403	Lep_receptor_Ig domain-containing protein. (92 aa)
	STAT4	Signal transducer and activator of transcription. (748 aa)
	ENSGGOP00000030478	Tyrosine-protein kinase. (1151 aa)
	STAT1	Signal transducer and activator of transcription. (777 aa)
	STAT3	Signal transducer and activator of transcription. (781 aa)
	JAK1	Tyrosine-protein kinase. (1154 aa)
	G3R8D3_GORGO	Epstein-Barr virus induced 3. (229 aa)
	IL27RA	Interleukin 27 receptor subunit alpha. (636 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
	IL6ST	Fibronectin type-III domain-containing protein. (329 aa)
	TYK2	Tyrosine-protein kinase. (1188 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CANX	G3R8D3_GORGO	ENSGGOP00000008258	ENSGGOP00000011637	Calnexin.	Epstein-Barr virus induced 3.	0.597
ENSGGOP00000030478	ENSGGOP00000048403	ENSGGOP00000030478	ENSGGOP00000048403	Tyrosine-protein kinase.	Lep_receptor_Ig domain-containing protein.	0.480
ENSGGOP00000030478	ENSGGOP00000049122	ENSGGOP00000030478	ENSGGOP00000049122	Tyrosine-protein kinase.	Uncharacterized protein.	0.480
ENSGGOP00000030478	IL12RB2	ENSGGOP00000030478	ENSGGOP00000006252	Tyrosine-protein kinase.	Interleukin 12 receptor subunit beta 2.	0.769
ENSGGOP00000030478	IL27RA	ENSGGOP00000030478	ENSGGOP00000011228	Tyrosine-protein kinase.	Interleukin 27 receptor subunit alpha.	0.937
ENSGGOP00000030478	IL6ST	ENSGGOP00000030478	ENSGGOP00000003666	Tyrosine-protein kinase.	Fibronectin type-III domain-containing protein.	0.480
ENSGGOP00000030478	JAK1	ENSGGOP00000030478	ENSGGOP00000016069	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.976
ENSGGOP00000030478	STAT1	ENSGGOP00000030478	ENSGGOP00000026987	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.977
ENSGGOP00000030478	STAT3	ENSGGOP00000030478	ENSGGOP00000020538	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.996
ENSGGOP00000030478	STAT4	ENSGGOP00000030478	ENSGGOP00000041604	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.759
ENSGGOP00000030478	TYK2	ENSGGOP00000030478	ENSGGOP00000005896	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.972
ENSGGOP00000048403	ENSGGOP00000030478	ENSGGOP00000048403	ENSGGOP00000030478	Lep_receptor_Ig domain-containing protein.	Tyrosine-protein kinase.	0.480
ENSGGOP00000048403	G3R8D3_GORGO	ENSGGOP00000048403	ENSGGOP00000011637	Lep_receptor_Ig domain-containing protein.	Epstein-Barr virus induced 3.	0.540
ENSGGOP00000048403	JAK1	ENSGGOP00000048403	ENSGGOP00000016069	Lep_receptor_Ig domain-containing protein.	Tyrosine-protein kinase.	0.587
ENSGGOP00000048403	TYK2	ENSGGOP00000048403	ENSGGOP00000005896	Lep_receptor_Ig domain-containing protein.	Tyrosine-protein kinase.	0.462
ENSGGOP00000049122	ENSGGOP00000030478	ENSGGOP00000049122	ENSGGOP00000030478	Uncharacterized protein.	Tyrosine-protein kinase.	0.480
ENSGGOP00000049122	G3R8D3_GORGO	ENSGGOP00000049122	ENSGGOP00000011637	Uncharacterized protein.	Epstein-Barr virus induced 3.	0.540
ENSGGOP00000049122	IL6ST	ENSGGOP00000049122	ENSGGOP00000003666	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.930
ENSGGOP00000049122	JAK1	ENSGGOP00000049122	ENSGGOP00000016069	Uncharacterized protein.	Tyrosine-protein kinase.	0.587
ENSGGOP00000049122	TYK2	ENSGGOP00000049122	ENSGGOP00000005896	Uncharacterized protein.	Tyrosine-protein kinase.	0.462